HECT ubiquitin ligase Smurf1 targets the tumor suppressor ING2 for ubiquitination and degradation

FEBS Letters

Volumn 584, Issue 14, 2010, Pages 3005-3012

  Nie, Jing ^a,b   Liu, Lin ^c   Wu, Min ^d   Xing, Guichun ^a,b   He, Shan ^e   Yin, Yuxin ^f   Tian, Chunyan ^a,b   He, Fuchu ^a,b   Zhang, Lingqiang ^a,b,d  

^a TSINGHUA UNIVERSITY   (China)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

^d ANHUI MEDICAL UNIVERSITY   (China)

^e BEIJING UNIVERSITY OF TECHNOLOGY   (China)

^f PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Inhibitor of growth 2; Protein degradation; Smad ubiquitination regulatory factor 1; Tumor suppressor; Ubiquitination

Indexed keywords

INHIBITOR OF GROWTH 2 PROTEIN; PROTEIN ING2; PROTEIN SMURF1; SMAD UBIQUITINATION REGULATORY FACTOR 1; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; GROWTH INHIBITOR; LIGASE; PROTEASOME; UBIQUITIN;

APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CELL STRAIN MCF 7; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; UBIQUITINATION; BIOCHEMISTRY; CHEMISTRY; GENETICS; METABOLISM; TUMOR SUPPRESSOR GENE;

BIOCHEMICAL PROCESSES; GENES, TUMOR SUPPRESSOR; GROWTH INHIBITORS; HUMANS; LIGASES; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITIN; UBIQUITINATION;

EID: 77954174209     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.05.033     Document Type: Article

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