The role of the NOP receptor in regulating food intake, meal pattern, and the excitability of proopiomelanocortin neurons

Neuropharmacology

Volumn 59, Issue 3, 2010, Pages 190-200

  Farhang, Borzoo ^a   Pietruszewski, Lindsay ^a   Lutfy, Kabirullah ^a   Wagner, Edward J ^a  

^a WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

Author keywords

Appetite; Glutamate; K+ channels; Nociceptin; NOP receptor; OFQ

Indexed keywords

G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL 1; GLUTAMIC ACID; NOCICEPTIN RECEPTOR; PROOPIOMELANOCORTIN; UNCLASSIFIED DRUG; NOCICEPTIN; OPIATE PEPTIDE; OPIATE RECEPTOR; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN;

ANIMAL EXPERIMENT; ANTERIOR HYPOTHALAMUS; ARTICLE; CONTROLLED STUDY; ENZYME RELEASE; EXCITATORY POSTSYNAPTIC POTENTIAL; FEEDING BEHAVIOR; FOOD INTAKE; GENE FREQUENCY; IMMUNOHISTOCHEMISTRY; MEMBRANE STEADY POTENTIAL; MOUSE; NONHUMAN; PATCH CLAMP; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; ANALYSIS OF VARIANCE; ANIMAL; BIOPHYSICS; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; ELECTROSTIMULATION; GENETICS; HYPOTHALAMUS; IN VITRO STUDY; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; PROCEDURES;

ANALYSIS OF VARIANCE; ANIMALS; APPETITE REGULATION; BIOPHYSICS; ELECTRIC STIMULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; FEEDING BEHAVIOR; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; HYPOTHALAMUS; MICE; MICE, KNOCKOUT; NEURONS; OPIOID PEPTIDES; PATCH-CLAMP TECHNIQUES; PRO-OPIOMELANOCORTIN; RECEPTORS, OPIOID; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN; IN VITRO TECHNIQUES;

EID: 77954142084     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.05.007     Document Type: Article

References (47)

1. 2+ channel current in rat sensory neurons by a G-protein-independent mechanism. J. Neurosci. 1997, 17:8721-8728.
2. Allen C.N., Jiang Z.-G., Teshima K., Darland T., Ikeda M., Nelson C.S., Quigley D.I., Yoshioka T., Allen R.G., Rea M.A., Grandy D.K. Orphanin-FQ/nociceptin (OFQ/N) modulates the activity of suprachiasmatic nucleus neurons. J. Neurosci. 1999, 19:2152-2160.
3. Appleyard S.M., Hayward M., Young J.I., Butler A.A., Cone R.D., Rubinstein M., Low M.J. A role for endogenous β-endorphin in energy homeostasis. Endocrinology 2003, 144:1753-1760.
4. Bajic D., Hoang Q.V., Nakajima S., Nakajima Y. Dissociated histaminergic neuron cultures from the tuberomammillary nucleus of rats: culture methods and ghrelin effects. J. Neurosci. Methods 2004, 132:177-184.
5. Bewick G.A., Dhillo W.S., Darch S.J., Murphy K.G., Gardiner J.V., Jethwa P.H., Kong W.M., Ghatei M.A., Bloom S.R. Hypothalamic cocaine- and amphetamine-regulated transcript (CART) and agouti-related protein (AgRP) neurons coexpress the NOP1 receptor and nociceptin alters CART and AgRP release. Endocrinology 2005, 146:3526-3534.
6. 2+] and cell excitability in primary cultures of rat cortical neurons. Neuropharmacology 2004, 47:873-883.
7. Blakley G.G., Pohorecky L.A., Benjamin D. Behavioral and endocrine changes following antisense oligonucleotide-induced reduction in the rat NOP receptor. Psychopharmacology (Berl.) 2004, 171:421-428.
8. Bomberg E.M., Grace M.K., Levine A.S., Olszewski P.K. Functional interaction between nociceptin/orphanin FQ and α-melanocyte-stimulating hormone in the regulation of feeding. Peptides 2006, 27:1827-1834.
9. Brann D.W., Mahesh V.B. Glutamate: a major neuroendocrine excitatory signal mediating steroid effects on gonadotropin secretion. J. Steroid Biochem. Mol. Biol. 1995, 53:325-329.
10. Bungo T., Shiraishi J., Yanagita K., Ohta Y., Fujita M. Effect of nociceptin/orphanin FQ on feeding behavior and hypothalamic neuropeptide expression in layer-type chicks. Gen. Comp. Endocrinol. 2009, 163:47-51.
11. Bunzow J.R., Saez C., Mortrud M., Bouvier C., Williams J.T., Low M., Grandy D.K. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or kappa opioid receptor type. FEBS Lett. 1994, 347:284-288.
12. 3-36. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:4695-4700.
13. Chen X., McClatchy D.B., Geller E.B., Liu-Chen L.-Y., Tallarida R.J., Adler M.W. Possible mechanism of hypothermia induced by intracerebroventricular injection of orphanin FQ/nociceptin. Brain Res. 2001, 904:252-258.
14. Connor M., Vaughan C.W., Chieng B., Christie M.J. Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro. Br. J. Pharmacol. 1996, 119:1614-1618.
15. 2+ in the SH-SY5Y human neuroblastoma cell line. Br. J. Pharmacol. 1996, 118:205-207.
16. Diaz S., Farhang B., Hoien J., Stahlman M., Adatia N., Cox J.M., Wagner E.J. Sex differences in the cannabinoid modulation of appetite, body temperature and neurotransmission at POMC synapses. Neuroendocrinology 2009, 89:424-440.
17. Economidou D., Policani F., Angellotti T., Massi M., Terada T., Ciccocioppo R. Effect of novel NOP receptor ligands in food intake in rats. Peptides 2006, 27:775-783.
18. Emmerson P.J., Miller R.J. Pre- and postsynaptic actions of opioid and orphan opioid agonists in the rat arcuate nucleus and ventromedial hypothalamus in vitro. J. Physiol. (Lond.) 1999, 517:431-445.
19. Gompf H.S., Moldavan M.G., Irwin R.P., Allen C.N. Nociceptin/orphanin FQ (N/OFQ) inhibits excitatory and inhibitory synaptic signaling in the suprachiasmatic nucleus (SCN). Neuroscience 2005, 132:955-965.
20. Ho J., Cox J.M., Wagner E.J. Cannabinoid-induced hyperphagia: correlation with inhibition of proopiomelanocortin neurons?. Physiol. Behav. 2007, 92:507-519.
21. Horvath T.L. The hardship of obesity: a soft-wired hypothalamus. Nat. Neurosci. 2005, 8:561-565.
22. Knoflach F., Reinscheid R.K., Civelli O., Kemp J.A. Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons. J. Neurosci. 1996, 16:6657-6664.
23. Koizumi M., Cagniard B., Murphy N.P. Endogenous nociceptin modulates diet preference independent of motivation and reward. Physiol. Behav. 2009, 97:1-13.
24. Lambert P.D., Couceyro P.R., McGirr K.M., Dall Vechia S.E., Smith Y., Kuhar M.J. CART peptides in the central control of feeding and interactions with neuropeptide Y. Synapse 1998, 29:293-298.
25. Matsushita H., Ishihara A., Mashiko S., Tanaka T., Kanno T., Iwaasa H., Ohta H., Kanatani A. Chronic intracerebroventricular infusion of nociceptin/orphanin FQ produces body weight gain by affecting both feeding and energy metabolism. Endocrinology 2009, 150:2668-2673.
26. Matthes H., Seward E.P., Kieffer B., North R.A. Functional selectivity of orphanin FQ for its receptor coexpressed with potassium channel subunits in Xenopus laevis oocytes. Mol. Pharmacol. 1996, 50:447-450.
27. Meis S., Pape H.-C. Control of glutamate and GABA release by nociceptin/orphanin FQ in the rat lateral amygdala. J. Physiol. (Lond.) 2001, 532:701-712.
28. 1 receptor. Nature 1995, 377:532-535.
29. Mollereau C., Parmentier M., Mailleux P., Butour J.-L., Moisand C., Chalon P., Caput D., Vassart G., Meunier J.-C. ORL1, a novel member of the opioid receptor family. FEBS Lett. 1994, 341:33-38.
30. Morgan C.A., Emmans G.C., Tolkamp B.J., Kyriazakis I. Analysis of the feeding behavior of pigs using different models. Physiol. Behav. 2000, 68:395-403.
31. Pan Z.Z., Hirakawa N., Fields H.L. A cellular mechanism for the bidirectional pain-modulating actions of orphanin FQ/nociceptin. Neuron 2000, 26:515-522.
32. Polidori C., Calo G., Ciccocioppo R., Guerrini R., Regoli D., Massi M. Pharmacological characterization of the nociceptin mediating hyperphagia: identification of a selective antagonist. Psychopharmacology (Berl.) 2000, 148:430-437.
33. Polidori C., de Caro G., Massi M. The hyperphagic effect of nociceptin/orphanin FQ in rats. Peptides 2000, 21:1051-1062.
34. Pomonis J.D., Billington C.J., Levine A.S. Orphanin FQ, agonist of the orphan opioid receptor, stimulates feeding in rats. Neuroreport 1996, 8:369-371.
35. Reinscheid R.K., Nothacker H.-P., Bourson A., Ardati A., Henningsen R.A., Bunzow J.R., Grandy D.K., Langen H., Monsma F.J., Civelli O. Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science 1995, 270:792-794.
36. Ronnekleiv O.K., Loose M.D., Erickson K.R., Kelly M.J. A method for immunocytochemical identification of biocytin-labeled neurons following intracellular recording. BioTechniques 1990, 9:432-438.
37. Rudy B. Diversity and ubiquity of K channels. Neuroscience 1988, 25:729-749.
38. Sinchak K., Dewing P., Cook M., Micevych P.E. Release of orphanin FQ/nociceptin in the medial preoptic nucleus and ventromedial nucleus of the hypothalamus facilitates lordosis. Horm. Behav. 2007, 51:406-412.
39. Sinchak K., Romeo H.E., Micevych P.E. Site-specific estrogen and progestin regulation of orphanin FQ/nociceptin and nociceptin opioid receptor mRNA expression in the female rat limbic hypothalamic system. J. Comp. Neurol. 2006, 496:252-268.
40. Stratford T.R., Holahan M.R., Kelley A.E. Injections of nociceptin into the nucleus accumbens shell or ventromedial hypothalamic nucleus increase food intake. Neuroreport 1997, 8:423-426.
41. Tajalli S., Jonaidi H., Abbasnejad M., Denbow D.M. Interaction between nociceptin/orphanin FQ (N/OFQ) and GABA in response to feeding. Physiol. Behav. 2006, 89:410-413.
42. Uezu K., Sei H., Sano A., Toida K., Suzuki-Yamamoto T., Houtani T., Sugimoto T., Takeshima H., Ishimura K., Morita Y. Lack of nociceptin receptor alters body temperature during resting period in mice. Neuroreport 2004, 15:751-755.
43. van den Pol A.N., Wuarin J.P., Dudek F.E. Glutamate, the dominant excitatory transmitter in neuroendocrine regulation. Science 1990, 250:1276-1278.
44. 1) ligand, nociceptin, of inwardly rectifying K conductance in dorsal raphe neurones. Br. J. Pharmacol. 1996, 117:1609-1611.
45. 1 receptor ligand nociceptin on membrane properties of rat periaqueductal gray neurons in vitro. J. Neurosci. 1997, 17:996-1003.
46. + conductance. Neuroendocrinology 1998, 67:73-82.
47. Zhang S., Yu L. Identification of dynorphins as endogenous ligands for an opioid receptor-like orphan receptor. J. Biol. Chem. 1995, 270:22772-22776.