Effects of nociceptin/orphanin FQ and endomorphin-1 on glutamate and GABA release, intracellular [Ca2+] and cell excitability in primary cultures of rat cortical neurons

Neuropharmacology

Volumn 47, Issue 6, 2004, Pages 873-883

  Bianchi, C ^a   Marani, L ^a   Barbieri, M ^a   Marino, S ^a   Beani, L ^a   Siniscalchi, A ^a  

^a UNIVERSITY OF FERRARA   (Italy)

Author keywords

Aminoacid release; Cell excitability; Endomorphin 1; Intracellular calcium; Nociceptin orphanin FQ; Primary neuronal cultures

Indexed keywords

4 AMINOBUTYRIC ACID; CALCIUM; DEXTRO ASPARTIC ACID; ENDOMORPHIN 1; GLUTAMIC ACID; NOCICEPTIN; PEPTIDE DERIVATIVE; TRITIUM;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFECT; ELECTRIC POTENTIAL; EXCITABILITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE;

ACTION POTENTIALS; ANALGESICS, OPIOID; ANIMALS; CALCIUM; CELLS, CULTURED; CEREBRAL CORTEX; ELECTRIC STIMULATION; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; ION CHANNEL GATING; NARCOTIC ANTAGONISTS; NEURONS; OLIGOPEPTIDES; OPIOID PEPTIDES; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID; TETRODOTOXIN; VASODILATOR AGENTS;

EID: 7444220080     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2004.06.017     Document Type: Article

References (65)

1. Alho H., Ferrarese C., Vicini S., Vaccarino F. Subsets of GABAergic neurons in dissociated cell cultures of neonatal rat cerebral cortex show co-localization with specific modulator peptides. Developmental Brain Research. 39:1988;193-204
2. Amano T., Matsubayashi H., Tamura Y., Takahashi T. Orphanin FQ-induced outward current in rat hippocampus. Brain Research. 853:2000;269-274
3. Barbieri M., Nistri A. Electrophysiological actions of N-[4-(4-fluorophenoxy)butyl]-4-piperinidyl]-N-methyl-2-benzothiazolamine (R56865) on CA1 neurons of the rat hippocampal slice during hypoxia. Neuroscience Letters. 270:1999;161-164
4. Beani L., Tomasini M.C., Govoni B.M., Bianchi C. Fluorimetric determination of electrically evoked increase in intracellular calcium in cultured cerebellar granule cells. Journal of Neuroscience Methods. 51:1994;1-7
5. 3H]D-aspartate outflow in primary cultures of rat neocortical neurons: effect of acute and long term nicotine treatment. Neuropharmacology. 39:2000;2646-2653
6. Berridge M.J. Neuronal calcium signaling. Neuron. 21:1998;13-26
7. Bianchi C., Beani L., Antonelli T., Vedovato M., Calò G., Tomasini M.C. A simple method for electrical field stimulation of cultured granule cells. Journal of Neuroscience Methods. 45:1992;175-182
8. 2 N-terminal tetrapeptide and discovery of a nociceptin receptor antagonist. Journal of Medicinal Chemistry. 41:1998;3360-3366
9. Calò G., Guerrini R., Rizzi A., Salvadori S., Regoli D. Pharmacology of nociceptin and its receptor: a novel therapeutic target. British Journal of Pharmacology. 129:2000;1261-1283
10. Chen L., Gu Y., Huang I.Y. The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphyn. Journal of Neuroscience. 15:1995;4602-4611
11. Chin J.H., Harris K., MacTavish D., Jhamandas J.H. Nociceptin/orphanin FQ modulation of ionic conductances in rat basal forebrain neurons. Journal of Pharmacology and Experimental Therapeutics. 303:2002;188-195
12. 2] is a competitive and selective antagonist at nociceptin/orphanin FQ receptors mediating K(+) channel activation in rat periaqueductal gray slices. Neuropharmacology. 42:2002;246-252
13. Christie M.J., Connor M., Vaughan C.W., Ingram S.L., Bagley E.E. Cellular actions of opioids and other analgesics: implications for synergism in pain relief. Clinical Experimental Pharmacology and Physiology. 27:2000;520-523
14. 2+ channel currents of acutely dissociated rat periaqueductal grey neurons. Journal of Physiology. 509:1998;47-58
15. Cousin M.A., Held B., Nicholls D.G. Exocytosis and selective neurite calcium responses in rat cerebellar granule cells during field stimulation. European Journal of Neuroscience. 7:1995;2379-2388
16. Cox B.M. Opioid receptors. The IUPHAR Compendium of Receptor Characterization and Classification. second ed. :2000;321-333 IUPHAR Media, London
17. De Felipe J., Fariñas I. The pyramidal neuron of the cerebral cortex: morphological and chemical characterization of the synaptic input. Progress in Neurobiology. 39:1992;563-607
18. De Vries T.J., Hogenboom F., Mulder A.H., Schoffelmeer A.N.M. Ontogeny of mu-, delta- and kappa-opioid receptors mediating inhibition of neurotransmitter release and adenylate cyclase activity in rat brain. Developmental Brain Research. 54:1990;63-69
19. Di Giannuario A., Pieretti S., Catalani A., Loizzo A. Orphanin FQ reduces morphine-induced dopamine release in the nucleus accumbens: a microdialysis study in rats. Neuroscience Letters. 272:1999;183-186
20. Emmerson P.J., Miller R.J. Pre- and postsynaptic actions of opioid and orphan opioid agonists in the rat arcuate nucleus and ventromedial hypothalamus in vitro. Journal of Physiology. 517:1999;431-445
21. Gavioli E.C., Marzola G., Guerrini R., Bertorelli R., Zucchini S., De Lima T.C., Rae G.A., Salvadori S., Regoli D., Calò G. Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidence from the mouse forced swimming test. European Journal of Neuroscience. 17:2003;1987-1990
22. Götz M., Bolz J. Differentiation of transmitter phenotypes in rat cerebral cortex. European Journal of Neuroscience. 6:1994;18-32
23. Higgins G.A., Kew J.N., Richards J.G., Takeshima H., Jenck F., Adam G., Wichmann J., Kemp J.A., Grottick A.J. A combined pharmacological and genetic approach to investigate the role of orphanin FQ in learning and memory. European Journal of Neuroscience. 15:2002;911-922
24. 2+ transients by a mu-opioid receptor agonist in dorsal horn neurons. Neuroreport. 8:1997;3061-3065
25. Ishii K., Murata A., Yoshimura K., Uyemura K. A novel monoclonal antibody K1 recognises early neurones in the rat cortex. Neuroscience Research. 39:2001;31-37
26. Jenck F., Moreau J.L., Martin J.R., Kilpatrick G.J., Reinscheid R.K., Monsma F.J. Jr., Nothacker H.P., Civelli O. Orphanin FQ acts as an anxiolytic to attenuate behavioral responses to stress. Proceedings of The National Academy of Sciences, USA. 94:1997;14854-14858
27. Knoflach F., Reinscheid R.K., Civelli O., Kemp J.A. Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons. Journal of Neuroscience. 16:1996;6657-6664
28. Krimer L.S., Goldman-Rakic P.S. Prefrontal microcircuits: membrane properties and excitatory input of local medium and wide arbor interneurites. Journal of Neuroscience. 21:2001;3788-3796
29. Lai C.C., Wu S.Y., Chen C.T., Dun N.J. Nociceptin inhibits rat sympathetic preganglionic neurons in situ and in vitro. American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 278:2000;R592-R597
30. MacDermott A.B., Role L.W., Siegelbaum S.A. Presynaptic ionotropic receptors and the control of transmitter release. Annual Review of Neuroscience. 22:1999;443-485
31. Madamba S.G., Schweitzer P., Siggins G.R. Nociceptin augments K currents in hippocampal CA1 neurons by both ORL-1 and opiate receptor mechanisms. Journal of Neurophysiology. 82:1999;1776-1785
32. Marti M., Stocchi S., Paganini F., Mela F., De Risi C., Calò G., Guerrini R., Barnes T.A., Lambert D.G., Beani L., Bianchi C., Morari M. Pharmacological profiles of presynaptic nociceptin/orphanin FQ receptors modulating 5-hydroxytryptamine and noradrenaline release in the rat neocortex. British Journal of Pharmacology. 138:2003;91-98
33. Martin G., Nie Z., Siggins G.R. mu-Opioid receptors modulate NMDA receptor-mediated responses in nucleus accumbens neurons. Journal of Neuroscience. 17:1997;11-22
34. Meis S., Pape H.C. Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to nociceptin/orphanin FQ. Journal of Neuroscience. 18:1998;8133-8144
35. Meis S., Pape H.C. Control of glutamate and GABA release by nociceptin/orphanin FQ in the rat lateral amygdala. Journal of Physiology. 532:2001;701-712
36. Meunier J.C. Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor. European Journal of Pharmacology. 340:1997;1-15
37. Meunier J.C., Mollereau C., Toll L., Suaudeau C., Moisand C., Alvinerie P., Butour J.L., Guillemot J.C., Ferrara P., Monsarrat B., Mazarguil H., Vassart G., Parmentier M., Costentin J. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature. 377:1995;532-535
38. Miller R.J. Presynaptic receptors. Annual Review of Pharmacology and Toxicology. 38:1998;201-227
39. Moran T.D., Abdulla F.A., Smith P.A. Cellular neurophysiological actions of nociceptin/orphanin FQ. Peptides. 21:2000;969-977
40. Mulder A., Schoffelmeer A. Multiple opioid receptors and presynaptic modulation of neurotransmitter release in the brain. Herz A. Handbook of Experimental Pharmacology. Opioids. vol. 104/1:1993;125-144 Springer Verlag, Berlin
41. Murphy N.P., Ly H.T., Maidment N.T. Intracerebroventricular orphanin FQ/nociceptin suppresses dopamine release in the nucleus accumbens of anaesthetized rats. Neuroscience. 75:1996;1-4
42. Murphy N.P., Lee Y., Maidment N.T. Orphanin FQ/nociceptin blocks acquisition of morphine place preference. Brain Research. 832:1999;168-170
43. Ostermeier A.M., Schlösser B., Schwender D., Sutor B. Activation of mu- and delta-opioid receptors causes presynaptic inhibition of glutamatergic excitation in neocortical neurons. Anesthesiology. 93:2000;1053-1063
44. Pan Z., Hirakawa N., Fields H.L. A cellular mechanism for the bidirectional pain-modulating action of orphanin FQ/nociceptin. Neuron. 26:2000;515-522
45. Redrobe J.P., Calò G., Regoli D., Quirion R. Nociceptin receptor antagonists display antidepressant-like properties in the mouse forced swimming test. Naunyn Schmiedeberg's Archives of Pharmacology. 365:2002;164-167
46. Reinscheid R.K., Nothacker H.P., Bourson A., Ardati A., Henningsen R.A., Bunzow J.R., Grandy D.K., Langen H., Monsma F.J. Jr., Civelli O. Orphanin FQ: a neuropeptide that activates an opioid like G protein-coupled receptor. Science. 270:1995;792-794
47. Richards D.A., Bliss T.V., Richards C.D. Differential modulation of NMDA-induced calcium transients by arachidonic acid and nitric oxide in cultured hippocampal neurons. European Journal of Neuroscience. 17:2003;2323-2328
48. Sbrenna S., Marti M., Morari M., Calò G., Guerrini R., Beani L., Bianchi C. L-glutamate and gamma-aminobutyric acid efflux from rat cerebrocortical synaptosomes: modulation by kappa- and mu- but not delta- and opioid receptor like-1 receptors. Journal of Pharmacology and Experimental Therapeutics. 291:1999;1365-1371
49. Sbrenna S., Marti M., Morari M., Calò G., Guerrini R., Beani L., Bianchi C. Modulation of 5-hydroxytryptamine efflux from rat cortical synaptosomes by opioids and nociceptin. British Journal of Pharmacology. 130:2000;425-433
50. Schlicker E., Morari M. Nociceptin/orphanin FQ and neurotransmitter release in the central nervous system. Peptides. 21:2000;1023-1029
51. Schlicker E., Werthwein S., Kathmann M., Bauer U. Nociceptin inhibits noradrenaline release in the mouse brain cortex via presynaptic ORL1 receptors. Naunyn Schmiedeberg's Archives of Pharmacology. 358:1998;418-422
52. Siniscalchi A., Rodi D., Morari M., Marti M., Cavallini S., Marino S., Beani L., Bianchi C. Direct and indirect inhibition by nociceptin/orphanin FQ on noradrenaline release from rodent cerebral cortex in vitro. British Journal of Pharmacology. 136:2002;1178-1184
53. Somogyi P., Tamas G., Lujan R., Buhl E.H. Salient features of synaptic organisation in the cerebral cortex. Brain Research Reviews. 26:1998;113-135
54. Spafford J.D., Zamponi G.W. Functional interactions between presynaptic calcium channels and the neurotransmitter release machinery. Current Opinion in Neurobiology. 13:2003;308-314
55. Stringer M., Makin M.K., Miles J., Morley J.S. D-Morphine but not L-morphine has low micromolar affinity for the non-competitive N-methyl-D-aspartate site in rat forebrain. Possible clinical implications for the management of neuropathic pain. Neuroscience Letters. 295:2000;21-24
56. Timmermann D.B., Lund T.M., Belhage B., Schousboe A. Localization and pharmacological characterization of voltage dependent calcium channels in cultured neocortical neurons. International Journal of Developmental Neuroscience. 19:2001;1-10
57. 3H]GABA release from cerebral cortical cultures: an in vitro approach for studying glutamate-induced neurotoxicity. Synapse. 30:1998;247-254
58. Trevisani M., Smart D., Gunthorpe M.J., Tognetto M., Barbieri M., Campi B., Amadesi S., Gray J., Jerman J.C., Broughm S.J., Owen D., Smith G.D., Randall A.D., Harrison S., Bianchi A., Davis J.B., Geppetti P. Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1. Nature Neuroscience. 5:2002;546-551
59. Valverde F., Facal-Valverde M.V., Santacana M., Heredia M. Development and differentiation of early generated cells of sublayer VIb in the somatosensory cortex of the rat: a correlated Golgi and autoradiographic study. Journal of Comparative Neurology. 290:1989;118-140
60. Vaughan C.W., Christie M.J. Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro. Journal of Physiology. 498:1997;463-472
61. Vaughan C.W., Ingram S.L., Christie M.J. Actions of the ORL1 receptor ligand nociceptin on membrane properties of rat periaqueductal gray neurons in vitro. Journal of Neuroscience. 17:1997;996-1003
62. Wamil A.W., McLean M.J. Use-, concentration- and voltage-dependent limitation by MK-801 of action potential firing frequency in mouse central neurons in cell culture. Journal of Pharmacology and Experimental Therapeutics. 260:1992;376-383
63. 2+ in cultured rat neocortical neurons. Neuroreport. 13:2002;1051-1056
64. Yamamoto T., Nozaki-Taguchi N., Kimura S. Analgesic effect of intrathecally administered nociceptin, an opioid receptor-like 1 receptor agonist, in the rat formalin test. Neuroscience. 81:1997;249-254
65. Yu T.P., Fein J., Phan T., Evans C.J., Xie C.W. Orphanin FQ inhibits synaptic transmission and long-term potentiation in rat hippocampus. Hippocampus. 7:1997;88-94