Orphanin-FQ/nociceptin (OFQ/N) modulates the activity of suprachiasmatic nucleus neurons

Journal of Neuroscience

Volumn 19, Issue 6, 1999, Pages 2152-2160

  Allen, Charles N ^a   Jiang, Zhi Gen ^a   Teshima, Koji ^a   Darland, Tristan ^a   Ikeda, Masayuki ^b   Nelson, Cole S ^a   Quigley, Denise I ^a   Yoshioka, Tohru ^b   Allen, Richard G ^a   Rea, Michael A ^c   Grandy, David K ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b WASEDA UNIVERSITY   (Japan)

^c AIR FORCE RESEARCH LABORATORY   (United States)

Author keywords

Calcium; Circadian rhythm; Nociceptin; Orphanin FQ; Potassium current; Suprachiasmatic nucleus

Indexed keywords

CALCIUM; NOCICEPTIN; POTASSIUM;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; CALCIUM TRANSPORT; CIRCADIAN RHYTHM; HYPERPOLARIZATION; IN SITU HYBRIDIZATION; MALE; MEMBRANE CONDUCTANCE; NERVE CELL; NONHUMAN; OPTIC CHIASM; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RADIOIMMUNOASSAY; RAT; REGULATORY MECHANISM; SUPRACHIASMATIC NUCLEUS;

EID: 0033560133     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-06-02152.1999     Document Type: Article

References (51)

1. Akaike N. Harata N (1994) Nystatin perforated patch recording and its application to analysis of intracellular mechanisms. Jpn J Physiol 44:433-473.
2. Bunzow JR, Saez C, Mortrud M, Bouvier C, Williams JT, Low M, Grandy DK (1994) Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not m, d or k opioid receptor type. FEBS Lett 347:284-288.
3. Card JP, Moore RY (1989) Organization of lateral geniculatehypothalamic connections in the rat. J Comp Neurol 284:135-147.
4. Darland T, Heinricher MM, Grandy DK (1998) Orphanin FQ/nociceptin: a role in pain and analgesia, but so much more. Trends Neurosci 21:215-221.
5. DC Vries MJ, Nunes Cardozo B, Van der Want J, De Wolf A, Meijer JH (1993) Glutamate immunoreactivity in terminals of the retinohypothalamic tract of the brown Norwegian rat. Brain Res 612:231-237.
6. DeCoursey PJ (1964) Function of a light response rhythm in hamsters. J Comp Physiol [A] 63:189-196.
7. Dißmann E, Wischmeyer E, Spauschus A, Pfeil D, Karschin C, Karschin A (1996) Functional expression and cellular mRNA localization of a G protein-activated K+ inward rectifier isolated from rat hrain. Biochem Biophys Res Commun 223:474-479.
8. Ding JM, Chen D. Weher ET, Faiman LE, Rea MA, Gillette MU (1994) Resetting the biological clock: mediation of nocturnal circadian shifts by glutamate and NO. Science 266:1713-1717.
9. Ding JM, Buchanan GF, Tischkau SA, Chen D, Kuriashkina L, Faiman LE, Alster JM, McPherson PS, Campbell KP. Gillette MU (1998) A neuronal ryanodine receptor mediates light-induced phase delays of the circadian clock. Nature 394:381-384.
10. Dodt H-U. Zieglgänsberger W (1990) Visualizing unstained neurons in living brain slices by infrared DIC-videomicroscopy. Brain Res 537:333-336.
11. Harrington ME, Rusak B (1986) Lesions of the thalamic intergeniculate leaflet alter hamster circadian rhythms. J Biol Rhythms 1:309-325.
12. Inouye S-IT (1996) Circadian rhythms of neuropeptides in the suprachiasmatic nucleus. In: Hypothalamic integration of circadian rhythms (Buijs RM, Kalsbeek A, Romijn HJ, Pennartz CMA, Mirmiran M, eds), pp 75-90. Amsterdam: Elsevier.
13. Jiang Z-G. Alien CN. North RA (1995a) Presynaptic inhibition by baclofen of retinohypothalamic excitatory synaptic transmission in rat suprachiasmatic nucleus. Neuroscience 64:813-819.
14. Jiang Z-G, Nelson CS, Alien CN (1995b) Melatonin activates an outward current and inhibits Ih in rat suprachiasmatic nucleus neurons. Brain Res 687:125-132.
15. Jiang Z-G. Yang Y-Q, Liu Z-P, Alien CN (1997) Membrane properties and synaptic inputs of suprachiasmatic nucleus neurons in rat brain slices. J Physiol (Lond) 499:141-159.
16. Karschin C, Schreibmayer W, Dascal N. Lester H, Davidson N, Karschin A (1994) Distribution and localization of G protein-coupled inwardly rectifying K ' channel in the rat. FEBS Lett 348:139-144.
17. Kim YI, Dudek FE (1991) Intracellular electrophysiological study of the suprachiasmatic nucleus neurons in rodents: excitatory synaptic mechanisms. J Physiol (Lond) 444:269-287.
18. Kofuji P, Davidson N, Lester HA (1995) Evidence that neuronal G-prolein-gated inwardly rectifying K+ channels are activated by Gβγ subunits and function as heteromullimers. Proc Natl Acad Sei USA 92:6542-6546.
19. Liou SY, Shibata S, Albers HE, Ueki S (1990) Effects of GABA and anxiolytics on the single unit discharge of suprachiasmatic neurons in rat hypothalamic slices. Brain Res Bull 25:103-107.
20. MacDermott AB, Mayer ML, Westbrook GL, Smith SJ, Barker JL (1986) NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones. Nature 321:519-522.
21. Mason R, Brooks A (1988) The electrophysiological effects of melatonin and a putative melatonin antagonist (N-acetyltryptamine) on rat suprachiasmatic neurones in vitro. Neurosci Lett 95:296-301.
22. Matthes H, Seward EP, Kieffer B, North R A (1996) Functional selectivity of orphanin FQ for its receptor coexpressed with potassium channel subunits in Xenopus laeris oocytes. Mol Pharmacol 50:447-450.
23. Meijcr JH, Groos GA (1988) Responsivencss of suprachiasmatic and ventral lateral geniculate neurons to serotonin and imipramine: a microiontophoretic study in normal and imipramine-treated rats. Brain Res Bull 20:89-96.
24. Meijer JH, Rietvcld WJ (1989) Neurophysiology of the suprachiasmatic circadian pacemaker in rodents. Physiol Rev 69:671-707.
25. 1 receptor. Nature 377:532-535.
26. Miller JD. Fuller CA (1990) The response of suprachiasmatic neurons of the rat hypothalamus to photic and serotonergic stimulation. Brain Res 515:155-162.
27. Moga MM, Moore RY (1997) Organization of neural inputs to the suprachiasmatic nucleus in the rat. J Comp Neurol 389:508-534.
28. Mogil JS, Griscl JF, Rcinscheid RK, Civelli O, Belknap JK, Grandy DK (1996) Orphanin FQ is a functional anti-opioid peptide. Neuroscience 75:333-337.
29. Mollereau C, Parmetier M, Mailleux P, Butour JL, Moisand C, Chalon P, Caput D, Vassart G, Meunier JC (1994) ORL1, a novel member of the opioid receptor family. Cloning, functional expression, and localization. FEBS Lett 341:33-38.
30. Mollereau C. Simons M-J, Soularue P, Liners F, Vassart G, Meunier J-C, Parmentier M (1996) Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene. Proc Natl Acad Sei USA 93:8666-8670.
31. Moore RY, Speh JC, Card JP (1995) The retinohypothalamic tract originates from a distinct subset of retinal ganglion cells. J Comp Neurol 352:351-366.
32. Morin LP (1994) The arcadian visual system. Brain Res Rev 19:102-127.
33. Morin LP, Blanchard J (1995) Organization of the hamster intergeniculate leaflet: NPY and ENK projections lo the suprachiasmatic nucleus, intergeniculate leaflet and posterior limitans nucleus. Vis Neurosci 12:57-67.
34. Nothacker H-P, Reinscheid RK, Mansour A, Henningsen RA, Ardati A, Monsma Jr FJ, Watson SJ, Civelli O (1996) Primary structure and tissue distribution of the orphanin FQ precursor. Proc Natl Acad Sei USA 93:8677-8682.
35. Pickard GE, Ralph MR, Menaker M (1987) The intergeniculate leaflet partially mediates effects of light on circadian rhythms. J Biol Rhythms 2:35-56.
36. 1. stimulates feeding in rats. NeuroReport 8:369-371.
37. 1-17-containing peptide produced in the rodent and monkey hypothalamus. Pcptidcs 19:133-139.
38. Rea MA, Buckley B, Lutton LM (1993) Local administration of EAA antagonists blocks light-induced phase shifts and c-fos expression in hamster SCN. Am J Physiol 254:R1191-R1198.
39. Rea MA, Glass JD, Colwell CS (1994) Serotonin modulates photic responses in the hamster suprachiasmatic nuclei. J Neurosci 14:3635-3642.
40. Reinscheid RK, Nothacker H-P. Bourson A, Ardati A. Henningsen RA, Bunzow JR, Grandy DK, Langen H. Monsma Jr FJ, Civelli O (1995) Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science 270:792-794.
41. Shibata S, Cassone VM, Moore RY (1989) Effects of melatonin on neuronal activity in the rat suprachiasmatic nucleus in vitro. Neurosci Lett 97:140-144.
42. Shinohara K, Tominaga K, Fukuhara C, Otori Y, Inouye S-T (1993) Processing of photic information within the intergeniculate leaflet of the lateral geniculate body: assessed by neuropeptide Y immunoreactivity in the suprachiasmatic nucleus of rats. Neuroscience 56:813-822.
43. Shirakawa T, Moore RY (1994) Glutamate shifts the phase of the circadian neuronal firing rhythm in the rat suprachiasmatic nucleus in vitro. Neurosci Lett 178:47-50.
44. Stehle J, Vanecek J, Vollrath L (1989) Effects of melatonin on spontaneous electrical activity of neurons in rat suprachiasmatic nuclei: an in vitro iontophoretic study. J Neural Transm 78:173-177.
45. Van den Pol AN, Tsujimoto KL (1985) Neurotransmitters of the hypothalamic suprachiasmatic nucleus: immunocytochemical analysis of 25 neuronal antigens. Neuroscience 15:1049-1086.
46. 1 ) ligand, nociceptin, of inwardly rectifying K conductance in dorsal raphe nucleus neurones. Br J Pharmacol 117:1609-1611.
47. Vaughan CW, Ingram SL, Christie MJ (1997) Actions of the ORL, receptor ligand nociceptin on membrane properties of rat periaqueductal gray neurons in vitro. J Neurosci 17:996-1003.
48. Wagner EJ, Rønnekleiv OK, Grandy DK, Kelly MJ (1998) The peptide orphanin FQ inhibits β-endorphin neurons and neurosecretory cells in the hypothalamic arcuate nucleus by activating an inwardly-rectifying K+ conductance. Neuroendocrinology 67:73-82.
49. Weber ET, Gannon RL, Michel AM, Gillette MU, Rea MA (1995a) Nitric oxide synthase inhibitor blocks light-induced phase shifts of the circadian activity rhythm, but not c-fos expression in the suprachiasmatic nucleus of the Syrian hamster. Brain Res 692:137-142.
50. Weber ET, Gannon RL, Rea MA (1995b) cGMP-dependent protein kinase inhibitor blocks light-induced phase advances of circadian rhythms in vivo. Neurosci Lett 197:227-230.
51. 2, a proposed antagonist of the nociceptin recepntor, is a potent and stable agonist in the rat spinal cord. Neurosci Lett 249:127-130.