N-acetylaspartic acid impairs enzymatic antioxidant defenses and enhances hydrogen peroxide concentration in rat brain

Metabolic Brain Disease

Volumn 25, Issue 2, 2010, Pages 251-259

  Pederzolli, Carolina Didonet ^a   Mescka, Caroline Paula ^a   Magnusson, Alessandra Selinger ^a   Deckmann, Kátia Bueno ^a   De Souza Streck, Evelise ^a   Sgaravatti, Ângela Malysz ^a   Sgarbi, Mirian Bonaldi ^a   Wyse, Angela T S ^a   Wannmacher, Clovis M D ^a   Wajner, Moacir ^a   Dutra Filho, Carlos S ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Canavan disease; Catalase; Glutathione peroxidase; Hydrogen peroxide; N Acetylaspartic acid; Rat brain

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; N ACETYLASPARTIC ACID; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANAVAN DISEASE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME KINETICS; IN VITRO STUDY; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PROTEIN DETERMINATION; RAT;

ANIMALS; ANTIOXIDANTS; ASPARTIC ACID; BRAIN; CANAVAN DISEASE; CATALASE; DRUG ADMINISTRATION SCHEDULE; FEMALE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; UP-REGULATION;

RATTUS;

EID: 77954084399     PISSN: 08857490     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11011-010-9202-1     Document Type: Article

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