Bone vascularization and trabecular bone formation are mediated by PKBalpha/Akt1 in a gene-dosage-dependent manner: In vivo and ex vivo MRI

Magnetic Resonance in Medicine

Volumn 64, Issue 1, 2010, Pages 54-64

  Vandoorne, Katrien ^a   Magland, Jeremy ^c   Plaks, Vicki ^a   Sharir, Amnon ^a,b   Zelzer, Elazar ^a   Wehrli, Felix ^c   Hemmings, Brian A ^d   Harmelin, Alon ^a   Neeman, Michal ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

Angiogenesis; Bone; CT; MRI; PKBalpha Akt1

Indexed keywords

BLOOD; BLOOD VESSELS; COMPUTERIZED TOMOGRAPHY; GENES; MAGNETIC RESONANCE IMAGING; MAMMALS;

ANGIOGENESIS; DOSE-DEPENDENT; HIGH SENSITIVITY; MACROMOLECULAR DYNAMICS; PKBALPHA/AKT1; REDUCED PERMEABILITIES; TRABECULAR BONES; VASCULARIZATION;

BONE;

PROTEIN KINASE B;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL PERMEABILITY; BLOOD VOLUME; BONE BLOOD FLOW; BONE DEVELOPMENT; BONE GROWTH; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CORTICAL BONE; EX VIVO STUDY; GENE DOSAGE; HUMERUS; IN VIVO STUDY; LONG BONE; MALE; METAPHYSIS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OSSIFICATION; SENSITIVITY ANALYSIS; TRABECULAR BONE; WILD TYPE; ANIMAL; BONE DENSITY; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; RADIOGRAPHY; VASCULARIZATION;

ANIMALS; BONE DENSITY; GENE DOSAGE; HUMERUS; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 77953921628     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.22395     Document Type: Article

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