Exploring structural requirements of 1-N-substituted thiocarbamoyl-3-phenyl-2-pyrazolines as antiamoebic agents using comparative QSAR modelling

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 14, 2010, Pages 4021-4026

  Adhikari, Nilanjan ^a   Maiti, Milan Kumar ^a   Jha, Tarun ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

Amoebiasis; FA MLR; PCRA; PLS; QSAR modelling; Stepwise regression

Indexed keywords

ANTIAMEBIC AGENT; CARBON; PYRAZOLINE DERIVATIVE; THIOCARBAMOYL 3 PHENYL 2 PYRAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; ATOM; CHEMICAL BOND; CONTROLLED STUDY; DRUG STRUCTURE; ELECTROPHILICITY; ENTAMOEBA HISTOLYTICA; NONHUMAN; PARTIAL LEAST SQUARES REGRESSION; POLARIZATION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATIC ELECTRICITY; SURFACE PROPERTY;

ANTIPROTOZOAL AGENTS; LEAST-SQUARES ANALYSIS; MODELS, MOLECULAR; PYRAZOLES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77953871469     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.05.098     Document Type: Article

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