Predictive comparative QSAR modelling of (phenylpiperazinyl-alkyl) oxindoles as selective 5-HT1A antagonists by stepwise regression, PCRA, FA-MLR and PLS techniques

European Journal of Medicinal Chemistry

Volumn 45, Issue 3, 2010, Pages 1119-1127

  Adhikari, Nilanjan ^a   Maiti, Milan K ^a   Jha, Tarun ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

(Phenylpiperazinyl alkyl) oxindoles; 5 HT1A receptor; FA MLR; PCRA; PLS; QSAR

Indexed keywords

CHLORINE; OXINDOLE; SEROTONIN 1A ANTAGONIST;

ARTICLE; ATOMIC PARTICLE; COMPARATIVE STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG STRUCTURE; MULTIPLE LINEAR REGRESSION ANALYSIS; PARTIAL LEAST SQUARES REGRESSION; PREDICTION; PRINCIPAL COMPONENT ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR BLOCKING;

COMPUTER SIMULATION; INDOLES; LINEAR MODELS; MODELS, MOLECULAR; MODELS, STATISTICAL; MOLECULAR STRUCTURE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTOR, SEROTONIN, 5-HT1A;

EID: 75849133191     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.12.011     Document Type: Article

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