Structural findings of 2-Phenylindole-3-carbaldehyde derivatives for antimitotic activity by FA-sMLR QSAR analysis

Chemical Biology and Drug Design

Volumn 75, Issue 2, 2010, Pages 204-213

  Halder, Amit K ^a,b   Adhikari, Nilanjan ^a   Jha, Tarun ^a  

^a JADAVPUR UNIVERSITY   (India)

^b Dr B C Roy College of Pharmacy and Allied Health Sciences   (India)

Author keywords

Antimitotic activity; Electrostatic potential charges; FA sMLR; K MCA; Quantitative structure activity relationship

Indexed keywords

2 PHENYLINDOLE 3 CARBALDEHYDE DERIVATIVE; ANTIMITOTIC AGENT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DRUG BINDING; ELECTRIC POTENTIAL; FACTORIAL ANALYSIS; HUMAN; HUMAN CELL; MATHEMATICAL COMPUTING; MITOSIS RATE; MULTIPLE LINEAR REGRESSION ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANTIMITOTIC AGENTS; CELL LINE, TUMOR; CLUSTER ANALYSIS; HUMANS; INDOLES; LINEAR MODELS; MODELS, CHEMICAL; MODELS, MOLECULAR; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SOFTWARE;

EID: 74549144346     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2009.00927.x     Document Type: Article

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