Ethanol-induced death of postnatal hippocampal neurons

Neurobiology of Disease

Volumn 10, Issue 3, 2002, Pages 396-409

  Moulder, Krista L ^a   Fu, Tao ^a   Melbostad, Heidi ^a   Cormier, Robert J ^a   Isenberg, Keith E ^a   Zorumski, Charles F ^a   Mennerick, Steven ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL; CALCIUM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POTASSIUM; SOMATOMEDIN C;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CALCIUM TRANSPORT; CELL CULTURE; CELL DEATH; CELL LOSS; CELL SURVIVAL; CONTROLLED STUDY; DEPOLARIZATION; HIPPOCAMPUS; LD 50; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0036406899     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1006/nbdi.2002.0523     Document Type: Article

References (50)

1. Bhave, S. V., & Hoffman, P. L. (1997) Ethanol promotes apoptosis in cerebellar granule cells by inhibiting the trophic effect of NMDA. J. Neurochem. 68, 578-586.
2. Blair, L. A., Bence-Hanulec, K. K., Mehta, S., Franke, T., Kaplan, D., & Marshall, J. (1999) Akt-dependent potentiation of L channels by insulin-like growth factor- 1 is required for neuronal survival. J. Neurosci. 19, 1940-1951.
3. Castoldi, A. F., Barni, S., Randine, G., Costa, L. G., & Manzo, L. (1998) Ethanol selectively interferes with the trophic action of NMDA and carbachol on cultured cerebellar granule neurons undergoing apoptosis. Brain Res. Dev. Brain Res. 111, 279-289.
4. Catlin, M. C., Guizzetti, M., & Costa, L. G. (1999) Effects of ethanol on calcium homeostasis in the nervous system: Implications for astrocytes. Mol. Neurobiol. 19, 1-24.
5. Collins, F., & Lile, J. D. (1989) The role of dihydropyridine-sensitive voltage-gated calcium channels in potassium-mediated neuronal survival. Brain Res. 502, 99-108.
6. Crews, F. T., Morrow, A. L., Criswell, H., & Breese, G. (1996) Effects of ethanol on ion channels. Int. Rev. Neurobiol. 39, 283-367.
7. Criswell, H. E., McCown, T. J., Ming, Z., Mueller, R. A., & Breese, G. R. (1999) Interactive role for neurosteroids in ethanol enhancement of gamma- aminobutyric acid-gated currents from dissociated substantia nigra reticulata neurons. J. Pharmacol. Exp. Ther. 291, 1054-1059.
8. Criswell H. E., Simson P. E., Duncan G. E., McCown T. J., Herbert J. S., Morrow A. L. & Breese G. R. (1993) Molecular basis for regionally specific action of ethanol on gamma-aminobutyric acidA receptors: Generalization to other ligand-gated ion channels. J Pharmacol. Exp. Ther. 267, 522-537.
9. Deshmukh, M., Vasilakos, J., Deckwerth, T. L., Lampe, P. A., Shivers, B. D., & Johnson, E. M., Jr. (1996) Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases. J. Cell Biol. 135, 1341-1354.
10. Dobbing, J., & Sands, J. (1979) Comparative aspects of the brain growth spurt. Early Hum. Dev. 3, 79-83.
11. Famy, C., Streissguth, A. P., & Unis, A. S. (1998) Mental illness in adults with fetal alcohol syndrome or fetal alcohol effects. Am. J. Psychiatry 155, 552-554.
12. Franklin, J. L., & Johnson, E. M., Jr. (1992) Suppression of programmed neuronal death by sustained elevation of cytoplasmic calcium. Trends Neurosci. 15, 501-508.
13. Galli, C., Meucci, O., Scorziello, A., Werge, T. M., Calissano, P., & Schettini, G. (1995) Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: The involvement of intracellular calcium and RNA synthesis. J. Neurosci. 15, 1172-1179.
14. Gallo, V., Kingsbury, A., Balazs, R., & Jorgensen, O. S. (1987) The role of depolarization in the survival and differentiation of cerebellar granule cells in culture. J. Neurosci. 7, 2203-2213.
15. Ghosh, A., Carnahan, J., & Greenberg, M. E. (1994) Requirement for BDNF in activity-dependent survival of cortical neurons. Science 263, 1618-1623.
16. Gruol, D. L., & Parsons, K. L. (1994) Chronic exposure to alcohol during development alters the calcium currents of cultured cerebellar Purkinje neurons. Brain Res. 634, 283-290.
17. Gwag, B. J., Koh, J. Y., DeMaro, J. A., Ying, H. S., Jacquin, M., & Choi, D. W. (1997) Slowly triggered excitotoxicity occurs by necrosis in cortical cultures. Neuroscience 77, 393-401.
18. Harris, R. A. (1999) Ethanol actions on multiple ion channels: which are important? Alcohol Clin. Exp. Res. 23, 1563-1570.
19. Harris, R. A., McQuilkin, S. J., Paylor, R., Abeliovich, A., Tonegawa, S., & Wehner, J. M. (1995) Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma- aminobutyrate type A receptors. Proc. Natl. Acad. Sci. USA 92, 3658-3662.
20. Ikonomidou, C., Bosch, F., Miksa, M., Bittigau, P., Vockler, J., Dikranian, K., Tenkova, T. I., Stefovska, V., Turski, L., & Olney, J. W. (1999) Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain. Science 283, 70-74.
21. Ikonomidou, C., Ishimaru, M. J., Wozniak, D. F., Koch, C., Bittigau, P., Price, M. T., Stefovska, V., Hörster, F., Tenkova, T., Dikranian, K., & Olney, J. W. (2000) Ethanol-induced apoptotic neurodegeneration and the fetal alcohol syndrome. Science 287, 1056-1060.
22. Isenberg, K. E., Bora, P. S., Zhou, X., Wu, X., Moore, B. W., & Lange, L. G. (1992) Nonoxidative ethanol metabolism: Expression of fatty acid ethyl ester synthase-III in cultured neural cells. Biochem. Biophys. Res. Commun. 185, 938-943.
23. Ishimaru, M. J., Ikonomidou, C., Tenkova, T. I., Der, T. C., Dikranian, K., Sesma, M. A., & Olney, J. W. (1999) Distinguishing excitotoxic from apoptotic neurodegeneration in the developing rat brain. J. Comp. Neurol. 408, 461-476.
24. Kelly, S. J., Day, N., & Streissguth, A. P. (2000) Effects of prenatal alcohol exposure on social behavior in humans and other species. Neurotoxicol. Teratol. 22, 143-149.
25. 2+ determine nerve growth factor dependence of sympathetic ganglion cells. Proc. Natl. Acad. Sci. USA 86, 6421-6425.
26. Lovinger, D. M., White, G., & Weight, F. F. (1989) Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science 243, 1721-1724.
27. Mattson, S. N., & Riley, E. P. (1998) A review of the neurobehavioral deficits in children with fetal alcohol syndrome or prenatal exposure to alcohol. Alcohol Clin. Exp. Res. 22, 279-294.
28. Mennerick, S., Que, J., Benz, A., & Zorumski, C. F. (1995) Passive and synaptic properties of neurons grown in microcultures and in mass cultures. J. Neurophysiol. 73, 320-332.
29. Mennerick, S., & Zorumski, C. F. (2000) Neural activity and survival in the developing nervous system. Mol. Neurobiol. 22, 41-54.
30. Messing, R. O., Carpenter, C. L., Diamond, I., & Greenberg, D. A. (1986) Ethanol regulates calcium channels in clonal neural cells. Proc. Natl. Acad. Sci. USA 83, 6213-6215.
31. Meyer-Franke, A., Wilkinson, G. A., Kruttgen, A., Hu, M., Munro, E., Hanson, M. G., Jr., Reichardt, L. F., & Barres, B. A. (1998) Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons. Neuron 21, 681-693.
32. Miller, T. M., Moulder, K. L., Knudson, C. M., Creedon, D. J., Deshmukh, M., Korsmeyer, S. J., & Johnson, E. M., Jr. (1997a) Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. J. Cell Biol. 139, 205-217.
33. Miller, T. M., Tansey, M. G., Johnson, E. M., Jr., & Creedon, D. J. (1997b) Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells. J. Biol. Chem. 272, 9847-9853.
34. 2+ current in hippocampal and dorsal root ganglion neurons of the rat. Mol. Pharmacol. 54, 559-568.
35. Peoples, R. W., White, G., Lovinger, D. M., & Weight, F. F. (1997) Ethanol inhibition of N-methyl-D-aspartate-activated current in mouse hippocampal neurones: Whole-cell patch-clamp analysis. Br. J. Pharmacol. 122, 1035-1042.
36. Popp, R. L., Lickteig, R. L., & Lovinger, D. M. (1999) Factors that enhance ethanol inhibition of N-methyl-D-aspartate receptors in cerebellar granule cells. J. Pharmacol. Exp. Ther. 289, 1564-1574.
37. Roebuck, T. M., Mattson, S. N., & Riley, E. P. (1998) A review of the neuroanatomical findings in children with fetal alcohol syndrome or prenatal exposure to alcohol. Alcohol Clin. Exp. Res. 22, 339-344.
38. Saito, M., Berg, M. J., Guidotti, A., & Marks, N. (1999) Gangliosides attenuate ethanol-induced apoptosis in rat cerebellar granule neurons. Neurochem. Res. 24, 1107-1115.
39. Samson, H. H., & Harris, R. A. (1992) Neurobiology of alcohol abuse. Trends Pharmacol. Sci. 13, 206-211.
40. A receptor-mediated chloride currents in hippocampal, cortical, and septal neurons in rat brain slices. Synapse 18, 94-103.
41. Thornberry, N. A., & Lazebnik, Y. (1998) Caspases: Enemies within. Science 281, 1312-1316.
42. Wafford, K. A., & Whiting, P. J. (1992) Ethanol potentiation of GABAA receptors requires phosphorylation of the alternatively spliced variant of the gamma 2 subunit. FEBS Lett. 313, 113-117.
43. Ward, G. R., & West, J. R. (1992) Effects of ethanol during development on neuronal survival and plasticity. In: Development of the Central Nervous System: Effects of Alcohol and Opiates (M. W. Miller, Ed.), pp. 109-138. Wiley-Liss, New York.
44. Wegelius, K., & Korpi, E. R. (1995) Ethanol inhibits NMDA-induced toxicity and trophism in cultured cerebellar granule cells. Acta Physiol. Scand. 154, 25-34.
45. Weight, F. F. (1992) Cellular and molecular physiology of alcohol actions in the nervous system. Int. Rev. Neurobiol. 33, 289-348.
46. Weiner, J. L., Gu, C., & Dunwiddie, T. V. (1997) Differential ethanol sensitivity of subpopulations of GABAA synapses onto rat hippocampal CA1 pyramidal neurons. J. Neurophysiol. 77, 1306-1312.
47. Wilson, M. R. (1998) Apoptosis: Unmasking the executioner. Cell Death Differ. 5, 646-652.
48. A receptor overactivation. J. Neurosci. 20, 3147-3156.
49. Yano, S., Tokumitsu, H., & Soderling, T. R. (1998) Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway. Nature 396, 584-587.
50. Zou, J. Y., Cohan, C., Rabin, R. A., & Pentney, R. J. (1995) Continuous exposure of cultured rat cerebellar macroneurons to ethanol- depressed NMDA and KCl-stimulated elevations of intracellular calcium. Alcohol Clin. Exp. Res. 19, 840-845.