Kainic acid-activated microglia mediate increased excitability of rat hippocampal neurons in vitro and in vivo: Crucial role of interleukin-1beta

NeuroImmunoModulation

Volumn 17, Issue 1, 2009, Pages 31-38

  Zheng, Honghua ^a,c   Zhu, Wei ^a   Zhao, Hu ^a   Wang, Xiaojing ^a   Wang, Wei ^b   Li, Zhengli ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c HUBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Hippocampal neurons; Hyperexcitability; Inducible nitric oxide synthase; Interleukin 1 ; Microglia; Microglial conditioned medium; N methyl D aspatate receptor subunit 1

Indexed keywords

INTERLEUKIN 1BETA; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN VENTRICLE; CELL ACTIVATION; CELL CULTURE; ELECTROPHYSIOLOGY; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MICROGLIA; NERVE CELL EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, NEUTRALIZING; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; ENCEPHALITIS; EPILEPSY; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; INTERLEUKIN-1BETA; KAINIC ACID; MALE; MICROGLIA; NERVE DEGENERATION; NEURONS; NEUROTOXINS; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; UP-REGULATION;

EID: 70349814833     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000243083     Document Type: Article

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