Upregulation of the GRIM-19 gene suppresses invasion and metastasis of human gastric cancer SGC-7901 cell line

Experimental Cell Research

Volumn 316, Issue 13, 2010, Pages 2061-2070

  Huang, Yi ^a   Yang, MeiHua ^b   Yang, Huaan ^c   Zeng, ZhaoChun ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c Yubei District People's Hospital   (China)

Author keywords

Gastric cancer; GRIM 19; GW112; Invasion; Metastasis; NF B

Indexed keywords

ADENOVIRUS VECTOR; GELATINASE A; GELATINASE B; GENE ASSOCIATED WITH RETINOID INTERFERON INDUCED MORTALITY PROTEIN 19; GENE PRODUCT; GLYCOPROTEIN; GW112 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; UNCLASSIFIED DRUG; UROKINASE; VASCULOTROPIN;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER INVASION; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; GENE REPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; LIVER METASTASIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN SECRETION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STOMACH CANCER; UPREGULATION; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE;

EID: 77953810539     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2010.05.010     Document Type: Article

References (48)

1. Lindner D.J., Borden E.C., Kalvakolanu D.V. Synergistic antitumor effects of a combination of interferons and retinoic acid on human tumor cells in vitro and in vivo. Clin. Cancer Res. 1997, 3:931-937.
2. Moore D.M., Kalvakolanu D.V., Lippman S.M., Kavanagh J.J., Hong W.K., Borden E.C., Paredes-Espinoza M., Krakoff I.H. Retinoic acid and interferon in human cancer: mechanistic and clinical studies. Semin. Hematol. 1994, 31:31-37.
3. Angell J.E., Lindner D.J., Shapiro P.S., Hofmann E.R., Kalvakolanu D.V. Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-β and retinoic acid combination, using a genetic approach. J. Biol. Chem. 2000, 275:33416-33426.
4. Huang G., Chen Y., Lu H., Cao X. Coupling mitochondrial respiratory chain to cell death: an essential role of mitochondrial complex I in the interferon-beta and retinoic acid-induced cancer cell death. Cell Death Differ. 2007, 14:327-337.
5. Alchanati I., Nallar S.C., Sun P., Gao L., Hu J., Stein A., Yakirevich E., Konforty D., Alroy I., Zhao X., Reddy S.P., Resnick M.B., Kalvakolanu D.V. A proteomic analysis reveals the loss of expression of the cell death regulatory gene GRIM-19 in human renal cell carcinomas. Oncogene 2006, 25:7138-7147.
6. Chidambaram N.V., Angell J.E., Ling W., Hofmann E.R., Kalvakolanu D.V. Chromosomal localization of human GRIM-19, a novel IFN-β and retinoic acid- activated regulator of cell death. J. Interferon Cytokine Res. 2000, 20:661-665.
7. Lufei C.C., Ma J., Huang G., Zhang T., Novotny-Diermayr V., Ong C.T., Cao X.M. GRIM-19, a death regulatory gene product, suppresses Stat3 activity via functional interaction. EMBO J. 2003, 22:1325-1335.
8. Zhang J., Yang J., Roy S.K., Tininini S., Hu J., Bromberg J.F., Poli V., Stark G.R., Kalvakolanu D.V. The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:9342-9347.
9. Kalakonda S., Nallar S.C., Gong P., Lindner D.J., Goldblum S.E., Reddy S.P., Kalvakolanu D.V. Tumor suppressive protein gene associated with retinoid-interferon-induced mortality (GRIM)-19 inhibits src-induced oncogenic transformation at multiple levels. Am. J. Pathol. 2007, 171:1352-1368.
10. Seo T., Lee D., Shim Y.S., Angell J.E., Chidambaram N.V., Kalvakolanu D.V., Choe J. Viral interferon regulatory factor 1 of Kaposi's sarcoma associated herpesvirus interacts with a cell death regulator, GRIM19, and inhibits interferon/retinoic acid-induced cell death. J. Virol. 2002, 76:8797-8807.
11. Zhang X., Huang Q., Yang Z., Li Y.P., Li C.Y. GW112, a novel antiapoptotic protein that promotes tumor growth. Cancer Res. 2004, 64:2474-2481.
12. Liu W., Chen L., Zhu J., Rodgers G.P. The glycoprotein hGC-1 binds to cadherin and lectins. Exp. Cell Res. 2006, 312:1785-1797.
13. Zhang J., Liu W.L., Tang D.C., Chen L., Wang M., Pack S.D., Zhuang Z., Rodgers G.P. Identification and characterization of a novel member of olfactomedin-related protein family, hGC-1, expressed during myeloid lineage development. Gene 2002, 283:83-93.
14. GW112/hGC-1 mRNA in colon, breast and lung cancer tissues detected using quantitative analysis. Cancer Sci. 2007, 98:315-320.
15. Yasui W., Oue N., Aung P.P., Matsumura S., Shutoh M., Nakayama H. Molecular-pathological prognostic factors of gastric cancer: a review. Gastric Cancer 2005, 8:86-94.
16. Aung P.P., Oue N., Mitani Y., Nakayama H., Yoshida K., Noguchi T., Bosserhoff A.K., Yasui W. Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metaloproteinase-10 are novel prognostic factors in patients with gastric cancer. Oncogene 2006, 25:2546-2557.
17. Liu W., Zhu J., Cao L., Rodgers G.P. Expression of hGC-1 is correlated with differentiation of gastric carcinoma. Histopathology 2007, 51:157-165.
18. Oue N., Aung P.P., Mitani Y., Kuniyasu H., Nakayama H., Yasui W. Genes involved in invasion and metastasis of gastric cancer identified by array-based hybridization and serial analysis of gene expression. Oncology 2005, 69:17-22.
19. Kobayashi D., Koshida S., Moriai R., Tsuji N., Watanabe N. Olfactomedin 4 promotes S-phase transition in proliferation of pancreatic cancer cells. Cancer Sci. 2007, 98:334-340.
20. He T.C., Zhou S., da Costa L.T., Yu J., Kinzler K.W., Vogelstein B. A simplified system for generating recombinant adenoviruses. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:2509-2514.
21. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2-δδ CT method. Methods 2001, 25:402-408.
22. Jin H.F., Pan Y.L., He L.J., Zhai H.H., Li X.H., Zhao L.N., Sun L., Liu J., Hong L., Song J.G., Xie H.H., Gao J.A., Han S., Li Y., Fan D. p75 Neurotrophin receptor inhibits invasion and metastasis of gastric cancer. Mol. Cancer Res. 2007, 5:423-433.
23. Pan Y., Zhao L., Liang J., Liu J., Shi Y., Liu N., Zhang G., Jin H., Gao J., Xie H., Wang J., Liu Z., Fan D. Cellular prion protein promotes invasion and metastasis of gastric cancer. FASEB J. 2006, 20:1205-1215.
24. Alberts S.R., Cervantes A., van de Velde C.J. Gastric cancer: epidemiology, pathology and treatment. Ann. Oncol. 2003, 14:31-36.
25. Tahara E. Molecular aspects of invasion and metastasis of stomach cancer. Verh. Dtsch Ges. Pathol. 2000, 84:43-49.
26. Zhang L., Gao L.F., Li Y., Lin G.M., Shao Y.T., Ji K., Yu H., Kalvakolanu D.V., Kopecko D.J., Zhao X.J., Xu D.Q., Hu J. Effects of plasmid-based Stat3-specific short hairpin RNA and GRIM-19 on PC-3M tumor cell growth. Clin. Cancer Res. 2008, 14:559-568.
27. Benihoud K., Yeh P., Perricaudet M. Adenovirus vectors for gene delivery. Curr. Opin. Biotechnol. 1999, 10:440-447.
28. Fearnley I.M., Carroll J., Shannon R.J., Runswick M.J., Walker J.E., Hirst J. GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH: ubiquinone oxidoreductase (complex I). J. Biol. Chem. 2001, 276:38345-38348.
29. Huang G., Lu H., Hao A., Ng D.C., Ponniah S., Guo K., Lufei C.C., Zeng Q., Caoj X.M. GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I. Mol. Cell. Biol. 2004, 24:8447-8456.
30. Chin K.L., Aerbajinai W., Zhu J., Drew L., Chen L., Liu W., Rodgers G.P. The regulation of OLFM4 expression in myeloid precursor cells relies on NF-[kappa] B transcription factor. Br. J. Haematol. 2008, 143:421-443.
31. Madrid L.V., Wang C.Y., Guttridge D.C., Schottelius A.J., Jr Baldwin A.S., Mayo M.W. Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-κB. Mol. Cell. Biol. 2000, 20:1626-1638.
32. Mansell A., Khelef N., Cossart P., O'Neill L.A. Internalin B activates nuclear factor-kB via Ras, phosphoinositide 3-kinase, and Akt. J. Biol. Chem. 2001, 276:43597-43603.
33. Lee B.L., Lee H.S., Jung J., Cho S.J., Chung H.Y., Kim W.H., Jin Y.W., Kim C.S., Nam S.Y. Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer. Clin. Cancer Res. 2005, 7:2518-2525.
34. Kim K.K., Park K.S., Song S.B., Kim K.E. Up regulation of GW112 Gene by NFκB promotes an antiapoptotic property in gastric cancer cells. Mol. Carcinog. 2010, 49:259-270.
35. Rayet B., Gélinas C. Aberrant rel/nfkb genes and activity in human cancer. Oncogene 1999, 18:6938-6947.
36. Sethi G., Ahn K.S., Sung B., Aggarwal B.B. Pinitol targets nuclear factor-κB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis. Mol. Cancer Ther. 2008, 7:1604-1614.
37. Li Q., Yu Y.Y., Zhu Z.G., Ji Y.B., Zhang Y., Liu B.Y., Chen X.H., Lin Y.Z. Effect of NF-kB constitutive activation on proliferation and apoptosis of gastric cancer cell lines. Eur. Surg. Res. 2005, 37:105-110.
38. Pahl H.L. Activators and target genes of Rel/NF-κB transcription factors. Oncogene 1999, 18:6853-6866.
39. Xie T.X., Wei D.Y., Liu M.G., Gao A.C., Ali-Osman F., Sawaya R., Huang S.Y. Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis. Oncogene 2004, 23:3550-3560.
40. Farina A.R., Tacconelli A., Vacca A., Maroder M., Gulino A., Mackay A.R. Transcriptional up-regulation of matrix metallo proteinase-9 expression during spontaneous epithelial to neuroblast phenotype conversion by SK-N-SH neuroblastoma cells, involved in enhanced invasivity, depends upon GT-box and nuclear factor κB elements. Cell Growth Differ. 1999, 10:353-367.
41. Bond M., Fabunmi R.P., Baker A.H., Newby A.C. Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: An absolute requirement for transcription factor NF-κB. FEBS Lett. 1998, 435:29-34.
42. Niu G., Wright K.L., Huang M., Song L., Haura E., Turkson J., Zhang S., Wang T., Sinibaldi D., Coppola D., Heller R., Ellis L.M., Karras J., Bromberg J., Pardoll D., Jove R., Yu H. Constitutive Stat3 activity upregulates VEGF expression and tumor angiogenesis. Oncogene 2002, 21:2000-2008.
43. Hooper A.T., Akiri G., Jin D., Shmelkov S.V., Chuang E., Shin S.J., Wu Y., Hicklin D.J., Rafii S., Vahdat L.T. VEGF receptor expression on reactive breast cancer stroma: paving the way for tumor invasion. J. Clin. Oncol. 2005, 23:9642-9650.
44. Cho J.Y., Chung H.C., Noh S.H., Roh J.K., Min J.S., Kim B.S. High level of urokinase-type plasminogen activator is a new prognostic marker in patients with gastric carcinoma. Cancer 1997, 79:878-883.
45. Kaneko T., Konno H., Baba M., Tanaka T., Nakamura S. Urokinase-type plasminogen activator expression correlates with tumor angiogenesis and poor outcome in gastric cancer. Cancer Sci. 2003, 94:43-49.
46. Wei D.Y., Le X.D., Zheng L.Z., Wang L.W., Frey J.A., Gao A.C., Peng Z.H., Huang S.Y., Xiong H.Q., Abbruzzese J.L., Xie K.P. Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. Oncogene 2003, 22:319-329.
47. Yu L.F., Zhu Y.B., Qiao M.M., Zhong J., Tu S.P., Wu Y.L. Constitutive activation and clinical significance of Stat3 in human gastric cancer tissues and cell lines. Zhong Hua Yi Xue Za Zhi 2004, 84:2064-2069.
48. Liu W., Liu Y., Zhu J., Wright E., Ding I., Rodgers G.P. Reduced hGC-1 protein expression is associated with malignant progression of colon carcinoma. Clin. Cancer Res. 2008, 14:1041-1049.