Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [18F]FMISO as hypoxia-selective tracer for PET

Nuclear Medicine and Biology

Volumn 37, Issue 5, 2010, Pages 565-575

  Bejot, Romain ^a   Kersemans, Veerle ^b   Kelly, Catherine ^b   Carroll, Laurence ^a   King, Robert C ^a   Gouverneur, Véronique ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

18F FMISO; Biomarker; Hypoxia; PET; Triazole; Tumour

Indexed keywords

1 FLUORO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL F 18; 3 NITRO 1,2,4 TRIAZOLE DERIVATIVE; NITROREDUCTASE; TRACER; XANTHINE OXIDASE; 1 FLUORO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL; BIOLOGICAL MARKER; GLUTATHIONE; MISONIDAZOLE; PROPANOL; TRIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CELL HYPOXIA; HUMAN; HUMAN CELL; ISOTOPE LABELING; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIATION DOSE; RADIATION EXPOSURE; TUMOR CELL; ANALOGS AND DERIVATIVES; ANIMAL; BIOLOGICAL MODEL; CELL TRANSFORMATION; CHEMISTRY; DIAGNOSTIC USE; DRUG SCREENING; FEMALE; KINETICS; METABOLISM; NEOPLASM; OXIDATION REDUCTION REACTION; PATHOLOGY; PHYSICAL CHEMISTRY; PROCEDURES; SCINTISCANNING; TUMOR CELL LINE;

ANIMALS; BIOLOGICAL MARKERS; CELL HYPOXIA; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DRUG EVALUATION, PRECLINICAL; FEMALE; GLUTATHIONE; KINETICS; MICE; MISONIDAZOLE; MODELS, BIOLOGICAL; NEOPLASMS; OXIDATION-REDUCTION; PHYSICOCHEMICAL PROCESSES; POSITRON-EMISSION TOMOGRAPHY; PROPANOLS; RADIOACTIVE TRACERS; TRIAZOLES; XANTHINE OXIDASE;

EID: 77953809615     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2010.03.011     Document Type: Article

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