2-Hydroxy-ceramide synthesis by ceramide synthase family: Enzymatic basis for the preference of FA chain length

Journal of Lipid Research

Volumn 49, Issue 11, 2008, Pages 2356-2364

  Mizutani, Yukiko ^a   Kihara, Akio ^a   Chiba, Hiroko ^a   Tojo, Hiromasa ^b   Igarashi, Yasuyuki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Epidermis; Fatty acid 2 hydroxylase; Hydroxy fatty acids; Keratinocytes

Indexed keywords

2 HYDROXY FATTY ACYL COENZYME A; 2 HYDROXYCERAMIDE; 2 HYDROXYCERAMIDE SYNTHASE; 2 HYDROXYSTEAROYL COENZYME A; ACYL COENZYME A; ACYL COENZYME A DESATURASE; CERAMIDE; CERAMIDE SYNTHASE 1; CERAMIDE SYNTHASE 2; CERAMIDE SYNTHASE 3; COENZYME A; FATTY ACID; FATTY ACID 2 HYDROXYLASE; MESSENGER RNA; NON HYDROXYCERAMIDE; OXYGENASE; SYNTHETASE; UNCLASSIFIED DRUG; DIHYDROCERAMIDE DESATURASE; FATTY ACID ALPHA HYDROXYLASE; FATTY ACID ALPHA-HYDROXYLASE; MIXED FUNCTION OXIDASE; OXIDOREDUCTASE;

ARTICLE; CELL DIFFERENTIATION; CELL STRAIN HEK293; CONTROLLED STUDY; EMBRYO; ENZYME ASSAY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; EPIDERMIS; FATTY ACID DESATURATION; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; KERATINOCYTE; KNOCKOUT GENE; LIPOGENESIS; NEWBORN; PRIORITY JOURNAL; BIOSYNTHESIS; CELL CULTURE; CELL LINE; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; ENZYMOLOGY; GENETICS; METABOLISM; MULTIGENE FAMILY; PHYSIOLOGY;

CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; CERAMIDES; FATTY ACIDS; HELA CELLS; HUMANS; INFANT, NEWBORN; KERATINOCYTES; MIXED FUNCTION OXYGENASES; MULTIGENE FAMILY; OXIDOREDUCTASES;

EID: 58149462858     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M800158-JLR200     Document Type: Article

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