-
1
-
-
9744277560
-
Nitroalkane oxidase, a carbanion-forming flavoprotein homologous to acyl-CoA dehydrogenase
-
Fitzpatrick, P. F., Orville, A. M., Nagpal, A., and Valley, M. P. (2005) Nitroalkane oxidase, a carbanion-forming flavoprotein homologous to acyl-CoA dehydrogenase Arch. Biochem. Biophys. 433, 157-165
-
(2005)
Arch. Biochem. Biophys.
, vol.433
, pp. 157-165
-
-
Fitzpatrick, P.F.1
Orville, A.M.2
Nagpal, A.3
Valley, M.P.4
-
2
-
-
0030570782
-
Kinetic mechanism and substrate specificity of nitroalkane oxidase
-
Heasley, C. J. and Fitzpatrick, P. F. (1996) Kinetic mechanism and substrate specificity of nitroalkane oxidase Biochem. Biophys. Res. Commun. 225, 6-10
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 6-10
-
-
Heasley, C.J.1
Fitzpatrick, P.F.2
-
3
-
-
0038298092
-
Inactivation of nitroalkane oxidase upon mutation of the active site base and rescue with a deprotonated substrate
-
Valley, M. P. and Fitzpatrick, P. F. (2003) Inactivation of nitroalkane oxidase upon mutation of the active site base and rescue with a deprotonated substrate J. Am. Chem. Soc. 23, 8738-8739
-
(2003)
J. Am. Chem. Soc.
, vol.23
, pp. 8738-8739
-
-
Valley, M.P.1
Fitzpatrick, P.F.2
-
4
-
-
1942485882
-
Carbanion versus hydride transfer mechanisms in flavoprotein-catalyzed dehydrogenations
-
Fitzpatrick, P. F. (2004) Carbanion versus hydride transfer mechanisms in flavoprotein-catalyzed dehydrogenations Bioorg. Chem. 32, 125-139
-
(2004)
Bioorg. Chem.
, vol.32
, pp. 125-139
-
-
Fitzpatrick, P.F.1
-
5
-
-
72049099611
-
Oxidation of amines by flavoproteins
-
Fitzpatrick, P. F. (2010) Oxidation of amines by flavoproteins Arch. Biochem. Biophys. 493, 13-25
-
(2010)
Arch. Biochem. Biophys.
, vol.493
, pp. 13-25
-
-
Fitzpatrick, P.F.1
-
6
-
-
58849100936
-
Hydride transfer made easy in the reaction of alcohol oxidation catalyzed by flavin-dependent oxidases
-
Gadda, G. (2008) Hydride transfer made easy in the reaction of alcohol oxidation catalyzed by flavin-dependent oxidases Biochemistry 47, 13745-13753
-
(2008)
Biochemistry
, vol.47
, pp. 13745-13753
-
-
Gadda, G.1
-
7
-
-
0038613012
-
Reductive half-reaction of nitroalkane oxidase: Effect of mutation of the active site aspartate to glutamate
-
Valley, M. P. and Fitzpatrick, P. F. (2003) Reductive half-reaction of nitroalkane oxidase: effect of mutation of the active site aspartate to glutamate Biochemistry 42, 5850-8566
-
(2003)
Biochemistry
, vol.42
, pp. 5850-8566
-
-
Valley, M.P.1
Fitzpatrick, P.F.2
-
8
-
-
0031054970
-
Identification of the naturally occurring flavin of nitroalkane oxidase from Fusarium oxysporum as a 5-nitrobutyl-FAD and conversion of the enzyme to the active FAD-containing form
-
Gadda, G., Edmondson, R. D., Russel, D. H., and Fitzpatrick, P. F. (1997) Identification of the naturally occurring flavin of nitroalkane oxidase from Fusarium oxysporum as a 5-nitrobutyl-FAD and conversion of the enzyme to the active FAD-containing form J. Biol. Chem. 272, 5563-5570
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5563-5570
-
-
Gadda, G.1
Edmondson, R.D.2
Russel, D.H.3
Fitzpatrick, P.F.4
-
9
-
-
13944254325
-
Establishing the kinetic competency of the cationic imine intermediate in nitroalkane oxidase
-
Valley, M. P., Tichy, S. E., and Fitzpatrick, P. F. (2005) Establishing the kinetic competency of the cationic imine intermediate in nitroalkane oxidase J. Am. Chem. Soc. 127, 2062-2066
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 2062-2066
-
-
Valley, M.P.1
Tichy, S.E.2
Fitzpatrick, P.F.3
-
10
-
-
31544467044
-
Crystal structures of nitroalkane oxidase: Insights into the reaction mechanism from a covalent complex of the flavoenzyme trapped during turnover
-
Nagpal, A., Valley, M. P., Fitzpatrick, P. F., and Orville, A. M. (2006) Crystal structures of nitroalkane oxidase: insights into the reaction mechanism from a covalent complex of the flavoenzyme trapped during turnover Biochemistry 45, 1138-1150
-
(2006)
Biochemistry
, vol.45
, pp. 1138-1150
-
-
Nagpal, A.1
Valley, M.P.2
Fitzpatrick, P.F.3
Orville, A.M.4
-
11
-
-
65249182105
-
Crystal structures of intermediates in the nitroalkane oxidase reaction
-
Héroux, A., Bozinovski, D. M., Valley, M. P., Fitzpatrick, P. F., and Orville, A. M. (2009) Crystal structures of intermediates in the nitroalkane oxidase reaction Biochemistry 48, 3407-3416
-
(2009)
Biochemistry
, vol.48
, pp. 3407-3416
-
-
Héroux, A.1
Bozinovski, D.M.2
Valley, M.P.3
Fitzpatrick, P.F.4
Orville, A.M.5
-
12
-
-
0034306863
-
Use of pH and kinetic isotope effects to dissect the effects of substrate size on binding and catalysis by nitroalkane oxidase
-
Gadda, G., Choe, D. Y., and Fitzpatrick, P. F. (2000) Use of pH and kinetic isotope effects to dissect the effects of substrate size on binding and catalysis by nitroalkane oxidase Arch. Biochem. Biophys. 382, 138-144
-
(2000)
Arch. Biochem. Biophys.
, vol.382
, pp. 138-144
-
-
Gadda, G.1
Choe, D.Y.2
Fitzpatrick, P.F.3
-
13
-
-
0033558778
-
Substrate specificity of a nitroalkane oxidizing enzyme
-
Gadda, G. and Fitzpatrick, P. F. (1999) Substrate specificity of a nitroalkane oxidizing enzyme Arch. Biochem. Biophys. 363, 309-313
-
(1999)
Arch. Biochem. Biophys.
, vol.363
, pp. 309-313
-
-
Gadda, G.1
Fitzpatrick, P.F.2
-
14
-
-
2442661476
-
Comparison of enzymatic and non-enzymatic nitroethane anion formation: Thermodynamics and contribution of tunneling
-
Valley, M. P. and Fitzpatrick, P. F. (2004) Comparison of enzymatic and non-enzymatic nitroethane anion formation: thermodynamics and contribution of tunneling J. Am. Chem. Soc. 126, 6244-6245
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 6244-6245
-
-
Valley, M.P.1
Fitzpatrick, P.F.2
-
15
-
-
0008305649
-
The principle of non-perfect synchronization
-
Bernasconi, C. F. (1992) The principle of non-perfect synchronization Adv. Phys. Org. Chem. 27, 119-238
-
(1992)
Adv. Phys. Org. Chem.
, vol.27
, pp. 119-238
-
-
Bernasconi, C.F.1
-
16
-
-
73949083862
-
Differential quantum mechanical tunneling in the uncatalyzed and in the nitroalkane oxidase catalyzed proton abstraction of nitroethane
-
Major, D. T., Heroux, A., Orville, A. M., Valley, M. P., Fitzpatrick, P. F., and Gao, J. (2009) Differential quantum mechanical tunneling in the uncatalyzed and in the nitroalkane oxidase catalyzed proton abstraction of nitroethane Proc. Natl. Acad. Sci. U.S.A. 106, 20734-20739
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 20734-20739
-
-
Major, D.T.1
Heroux, A.2
Orville, A.M.3
Valley, M.P.4
Fitzpatrick, P.F.5
Gao, J.6
-
17
-
-
0037022634
-
Cloning of nitroalkane oxidase from Fusarium oxysporum identifies a new member of the acyl-CoA dehydrogenase superfamily
-
Daubner, S. C., Gadda, G., Valley, M. P., and Fitzpatrick, P. F. (2002) Cloning of nitroalkane oxidase from Fusarium oxysporum identifies a new member of the acyl-CoA dehydrogenase superfamily Proc. Natl. Acad. Sci. U.S.A. 99, 2702-2707
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 2702-2707
-
-
Daubner, S.C.1
Gadda, G.2
Valley, M.P.3
Fitzpatrick, P.F.4
-
18
-
-
0842265784
-
Acyl-CoA dehydrogenases and acyl-CoA oxidases. Structural basis for mechanistic similarities and differences
-
Kim, J. J. and Miura, R. (2004) Acyl-CoA dehydrogenases and acyl-CoA oxidases. Structural basis for mechanistic similarities and differences Eur. J. Biochem. 271, 483-493
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 483-493
-
-
Kim, J.J.1
Miura, R.2
-
19
-
-
0029040665
-
Structure and mechanism of action of the acyl-CoA dehydrogenases
-
Thorpe, C. and Kim, J. P. (1995) Structure and mechanism of action of the acyl-CoA dehydrogenases FASEB J. 9, 718-725
-
(1995)
FASEB J.
, vol.9
, pp. 718-725
-
-
Thorpe, C.1
Kim, J.P.2
-
20
-
-
36849089004
-
Mechanistic and structural analyses of the roles of Arg409 and Asp402 in the reaction of the flavoprotein nitroalkane oxidase
-
Fitzpatrick, P. F., Valley, M. P., Bozinovski, D. M., Shaw, P. G., Héroux, A., and Orville, A. M. (2007) Mechanistic and structural analyses of the roles of Arg409 and Asp402 in the reaction of the flavoprotein nitroalkane oxidase Biochemistry 46, 13800-13808
-
(2007)
Biochemistry
, vol.46
, pp. 13800-13808
-
-
Fitzpatrick, P.F.1
Valley, M.P.2
Bozinovski, D.M.3
Shaw, P.G.4
Héroux, A.5
Orville, A.M.6
-
21
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
-
Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs Nucleic Acids Res. 25, 3389-3402
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
22
-
-
0842330598
-
Acyl-CoA dehydrogenases. A mechanistic overview
-
Ghisla, S. and Thorpe, C. (2004) Acyl-CoA dehydrogenases. A mechanistic overview Eur. J. Biochem. 271, 494-508
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 494-508
-
-
Ghisla, S.1
Thorpe, C.2
-
23
-
-
0032574753
-
Biochemical and physical characterization of the active FAD-containing form of nitroalkane oxidase from Fusarium oxysporum
-
Gadda, G. and Fitzpatrick, P. F. (1998) Biochemical and physical characterization of the active FAD-containing form of nitroalkane oxidase from Fusarium oxysporum Biochemistry 37, 6154-6164
-
(1998)
Biochemistry
, vol.37
, pp. 6154-6164
-
-
Gadda, G.1
Fitzpatrick, P.F.2
-
24
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski, Z. and Minor, W. (1997) Processing of X-ray diffraction data collected in oscillation mode Methods Enzymol. 276, 307-326
-
(1997)
Methods Enzymol.
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
25
-
-
34447508216
-
Phaser crystallographic software
-
McCoy, A. J., Grosse-Kunstleve, R. W., Adams, P. D., Winn, M. D., Storoni, L. C., and Read, R. J. (2007) Phaser crystallographic software J. Appl. Crystallogr. 40, 658-674
-
(2007)
J. Appl. Crystallogr.
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
Grosse-Kunstleve, R.W.2
Adams, P.D.3
Winn, M.D.4
Storoni, L.C.5
Read, R.J.6
-
26
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
Adams, P. D., Afonine, P. V., Bunkoczi, G., Chen, V. B., Davis, I. W., Echols, N., Headd, J. J., Hung, L.-W., Kapral, G. J., Grosse-Kunstleve, R. W., McCoy, A. J., Moriarty, N. W., Oeffner, R., Read, R. J., Richardson, D. C., Richardson, J. S., Terwilliger, T. C., and Zwart, P. H. (2010) PHENIX: a comprehensive Python-based system for macromolecular structure solution Acta Crystallogr. D 66, 213-221
-
(2010)
Acta Crystallogr. D
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
Afonine, P.V.2
Bunkoczi, G.3
Chen, V.B.4
Davis, I.W.5
Echols, N.6
Headd, J.J.7
Hung, L.-W.8
Kapral, G.J.9
Grosse-Kunstleve, R.W.10
McCoy, A.J.11
Moriarty, N.W.12
Oeffner, R.13
Read, R.J.14
Richardson, D.C.15
Richardson, J.S.16
Terwilliger, T.C.17
Zwart, P.H.18
-
28
-
-
0034673150
-
Mechanism of nitroalkane oxidase: 2. pH and kinetic isotope effects
-
Gadda, G. and Fitzpatrick, P. F. (2000) Mechanism of nitroalkane oxidase: 2. pH and kinetic isotope effects Biochemistry 39, 1406-1410
-
(2000)
Biochemistry
, vol.39
, pp. 1406-1410
-
-
Gadda, G.1
Fitzpatrick, P.F.2
-
29
-
-
0018690805
-
Plotting methods for analyzing enzyme rate data
-
Rudolph, F. B. and Fromm, H. J. (1979) Plotting methods for analyzing enzyme rate data Methods Enzymol. 63, 138-159
-
(1979)
Methods Enzymol.
, vol.63
, pp. 138-159
-
-
Rudolph, F.B.1
Fromm, H.J.2
-
30
-
-
50549204004
-
D -Amino acid oxidase. II. Specificity, competitive inhibition and reaction sequence
-
Dixon, M. and Kleppe, K. (1965) d -Amino acid oxidase. II. Specificity, competitive inhibition and reaction sequence Biochim. Biophys. Acta 96, 368-382
-
(1965)
Biochim. Biophys. Acta
, vol.96
, pp. 368-382
-
-
Dixon, M.1
Kleppe, K.2
-
31
-
-
0033773601
-
High-level expression of human liver monoamine oxidase B in Pichia pastoris
-
Newton-Vinson, P., Hubalek, F., and Edmondson, D. E. (2000) High-level expression of human liver monoamine oxidase B in Pichia pastoris Protein Expression Purif. 20, 334-345
-
(2000)
Protein Expression Purif.
, vol.20
, pp. 334-345
-
-
Newton-Vinson, P.1
Hubalek, F.2
Edmondson, D.E.3
-
32
-
-
0037031276
-
Monomeric sarcosine oxidase: Role of histidine 269 in catalysis
-
Zhao, G., Song, H., Chen, Z., Mathews, S., and Jorns, M. S. (2002) Monomeric sarcosine oxidase: role of histidine 269 in catalysis Biochemistry 41, 9751-9764
-
(2002)
Biochemistry
, vol.41
, pp. 9751-9764
-
-
Zhao, G.1
Song, H.2
Chen, Z.3
Mathews, S.4
Jorns, M.S.5
-
33
-
-
67049098986
-
Use of pH and kinetic isotope effects to establish chemistry as rate-limiting in oxidation of a peptide substrate by LSD1
-
Gaweska, H., Henderson Pozzi, M., Schmidt, D. M. Z., McCafferty, D. G., and Fitzpatrick, P. F. (2009) Use of pH and kinetic isotope effects to establish chemistry as rate-limiting in oxidation of a peptide substrate by LSD1 Biochemistry 48, 5440-5445
-
(2009)
Biochemistry
, vol.48
, pp. 5440-5445
-
-
Gaweska, H.1
Henderson Pozzi, M.2
Schmidt, D.M.Z.3
McCafferty, D.G.4
Fitzpatrick, P.F.5
-
34
-
-
77953538248
-
A lysine conserved in the monoamine oxidase family is involved in oxidation of the reduced flavin in mouse polyamine oxidase
-
(2010). (in press)
-
Henderson Pozzi, M. and Fitzpatrick, P. F. (2010) A lysine conserved in the monoamine oxidase family is involved in oxidation of the reduced flavin in mouse polyamine oxidase. Arch. Biochem. Biophys. (in press).
-
Arch. Biochem. Biophys.
-
-
Henderson Pozzi, M.1
Fitzpatrick, P.F.2
-
35
-
-
0028961335
-
SCOP: A structural classification of proteins database for the investigation of sequences and structures
-
Murzin, A. G., Brenner, S. E., Hubbard, T., and Chothia, C. (1995) SCOP: a structural classification of proteins database for the investigation of sequences and structures J. Mol. Biol. 247, 536-540
-
(1995)
J. Mol. Biol.
, vol.247
, pp. 536-540
-
-
Murzin, A.G.1
Brenner, S.E.2
Hubbard, T.3
Chothia, C.4
-
36
-
-
28444447058
-
Solvent polarization and kinetic isotope effects in nitroethane deprotonation and implications to the nitroalkane oxidase reaction
-
Major, D. T., York, D. M., and Gao, J. (2005) Solvent polarization and kinetic isotope effects in nitroethane deprotonation and implications to the nitroalkane oxidase reaction J. Am. Chem. Soc. 127, 16374-16375
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 16374-16375
-
-
Major, D.T.1
York, D.M.2
Gao, J.3
|