Gene expression profile of endothelial cells exposed to estrogenic environmental compounds: Implications to pulmonary vascular lesions

Life Sciences

Volumn 86, Issue 25-26, 2010, Pages 919-927

  Felty, Quentin ^a   Yoo, Changwon ^a   Kennedy, Amy ^a  

^a FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

Estrogen; Polychlorinated biphenyls (PCBs); Vascular lesion

Indexed keywords

ESTRADIOL; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; NOTCH3 RECEPTOR; POLYCHLORINATED BIPHENYL DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ARTICLE; CARDIOVASCULAR SYSTEM; CELL ADHESION; CELL GROWTH; CONTROLLED STUDY; ENDOTHELIUM CELL; ENVIRONMENTAL EXPLOITATION; ESTROGEN ACTIVITY; GENE ACTIVATION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; INFLAMMATION; LUNG DISEASE; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RISK FACTOR; SIGNAL TRANSDUCTION; VASCULAR DISEASE; VASCULAR ENDOTHELIUM; VASCULARIZATION;

BAYES THEOREM; CELL LINE; CLUSTER ANALYSIS; DOWN-REGULATION; ENDOTHELIAL CELLS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; ESTROGENS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; LUNG; MICROVESSELS; NEOVASCULARIZATION, PATHOLOGIC; POLYMERASE CHAIN REACTION; UP-REGULATION;

EID: 77953616682     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.04.007     Document Type: Article

References (43)

1. The Coronary Drug Project. Initial findings leading to modifications of its research protocol. JAMA 1970, 214(7):1303-1313. Anon.
2. The Coronary Drug Project. Findings leading to discontinuation of the 2.5-mgday estrogen group. The Coronary Drug Project Research Group. JAMA 1973, 226(6):652-657. Anon.
3. Arteaga E., Villaseca P., Bianchi M., Rojas A., Marshall G. Raloxifene is a better antioxidant of low-density lipoprotein than estradiol or tamoxifen in postmenopausal women in vitro. Menopause 2003, 10(2):142-146.
4. Bitman J., Cecil H.C. Estrogenic activity of DDT analogs and polychlorinated biphenyls. Journal of Agricultural and Food Chemistry 1970, 18(6):1108-1112.
5. Bocchinfuso W.P., Hively W.P., Couse J.F., Varmus H.E., Korach K.S. A mouse mammary tumor virus-Wnt-1 transgene induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-alpha. Cancer Research 1999, 59(8):1869-1876.
6. Caulin-Glaser T., Watson C.A., Pardi R., Bender J.R. Effects of 17beta-estradiol on cytokine-induced endothelial cell adhesion molecule expression. The Journal of Clinical Investigation 1996, 98(1):36-42.
7. Chambliss K.L., Yuhanna I.S., Anderson R.G., Mendelsohn M.E., Shaul P.W. ERbeta has nongenomic action in caveolae. Molecular Endocrinology 2002, 16(5):938-946.
8. Choi W., Eum S.Y., Lee Y.W., Hennig B., Robertson L.W., Toborek M. PCB 104-induced proinflammatory reactions in human vascular endothelial cells: relationship to cancer metastasis and atherogenesis. Toxicological Sciences 2003, 75(1):47-56.
9. Cid M.C., Kleinman H.K., Grant D.S., Schnaper H.W., Fauci A.S., Hoffman G.S. Estradiol enhances leukocyte binding to tumor necrosis factor (TNF)-stimulated endothelial cells via an increase in TNF-induced adhesion molecules E-selectin, intercellular adhesion molecule type 1, and vascular cell adhesion molecule type 1. The Journal of Clinical Investigation 1994, 93(1):17-25.
10. Cid M.C., Esparza J., Schnaper H.W., Juan M., Yague J., Grant D.S., Urbano-Marquez A., Hoffman G.S., Kleinman H.K. Estradiol enhances endothelial cell interactions with extracellular matrix proteins via an increase in integrin expression and function. Angiogenesis 1999, 3(3):271-280.
11. Cid M.C., Schnaper H.W., Kleinman H.K. Estrogens and the vascular endothelium. Annals of the New York Academy of Sciences 2002, 966:143-157.
12. Cox R.L., Crawford E.D. Estrogens in the treatment of prostate cancer. The Journal of Urology 1995, 154(6):1991-1998.
13. Davey J.C., Bodwell J.E., Gosse J.A., Hamilton J.W. Arsenic as an endocrine disruptor: effects of arsenic on estrogen receptor-mediated gene expression in vivo and in cell culture. Toxicological Sciences 2007, 98(1):75-86.
14. Davies R.J., Morrell N.W. Molecular mechanisms of pulmonary arterial hypertension: role of mutations in the bone morphogenetic protein type II receptor. Chest 2008, 134(6):1271-1277.
15. Dumond J.W., Singh K.P., Roy D. Regulation of the growth of mouse Leydig cells by the inactive stereoisomer, 17alpha-estradiol: lack of correlation between the elevated expression of ERalpha and difference in sensitivity to estradiol isomers. Oncology Reports 2001, 8(4):899-902.
16. Eum S.Y., Lee Y.W., Hennig B., Toborek M. VEGF regulates PCB 104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells. Experimental Cell Research 2004, 296(2):231-244.
17. Eum S.Y., Andras I., Hennig B., Toborek M. NADPH oxidase and lipid raft-associated redox signaling are required for PCB153-induced upregulation of cell adhesion molecules in human brain endothelial cells. Toxicology and Applied Pharmacology 2009, 240(2):299-305.
18. Felty Q. Estrogen-induced DNA synthesis in vascular endothelial cells is mediated by ROS signaling. BMC Cardiovascular Disorders 2006, 6:16.
19. Felty Q., Porther N. Estrogen-induced redox sensitive Id3 signaling controls the growth of vascular cells. Atherosclerosis 2008, 198(1):12-21.
20. Goncharov A., Haase R.F., Santiago-Rivera A., Morse G., Mccaffrey R.J., Rej R., Carpenter D.O. High serum PCBs are associated with elevation of serum lipids and cardiovascular disease in a Native American population. Environmental Research 2008, 106(2):226-239.
21. Gustavsson P., Hogstedt C. A cohort study of Swedish capacitor manufacturing workers exposed to polychlorinated biphenyls (PCBs). American Journal of Industrial Medicine 1997, 32(3):234-239.
22. Hay A., Tarrel J. Mortality of power workers exposed to phenoxy herbicides and polychlorinated biphenyls in waste transformer oil. Annals of the New York Academy of Sciences 1997, 837:138-156.
23. Hennig B., Hammock B.D., Slim R., Toborek M., Saraswathi V., Robertson L.W. PCB-induced oxidative stress in endothelial cells: modulation by nutrients. International Journal of Hygiene and Environmental Health 2002, 205(1-2):95-102.
24. Howard B.V., Hsia J., Ouyang P., Van V.L., Lindsay J., Silverman A., Alderman E.L., Tripputi M., Waters D.D. Postmenopausal hormone therapy is associated with atherosclerosis progression in women with abnormal glucose tolerance. Circulation 2004, 110(2):201-206.
25. Hyduk A., Croft J.B., Ayala C., Zheng K., Zheng Z.J., Mensah G.A. Pulmonary hypertension surveillance-United States, 1980-2002. MMWR Surveillance Summary 2005, 54(5):1-28.
26. Irey N.S., Norris H.J. Intimal vascular lesions associated with female reproductive steroids. Archives of Pathology 1973, 96(4):227-234.
27. Kim-Schulze S., Mcgowan K.A., Hubchak S.C., Cid M.C., Martin M.B., Kleinman H.K., Greene G.L., Schnaper H.W. Expression of an estrogen receptor by human coronary artery and umbilical vein endothelial cells. Circulation 1996, 94(6):1402-1407.
28. Kleiger R.E., Boxer M., Ingham R.E., Harrison D.C. Pulmonary hypertension in patients using oral contraceptives. A report of six cases. Chest 1976, 69(2):143-147.
29. Li X., Zhang X., Leathers R., Makino A., Huang C., Parsa P., Macias J., Yuan J.X., Jamieson S.W., Thistlethwaite P.A. Notch3 signaling promotes the development of pulmonary arterial hypertension. Nature Medicine 2009, 15(11):1289-1297.
30. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25(4):402-408.
31. Meek M.D., Finch G.L. Diluted mainstream cigarette smoke condensates activate estrogen receptor and aryl hydrocarbon receptor-mediated gene transcription. Environmental Research 1999, 80(1):9-17.
32. Newman J.H., Fanburg B.L., Archer S.L., Badesch D.B., Barst R.J., Garcia J.G., Kao P.N., Knowles J.A., Loyd J.E., Mcgoon M.D., Morse J.H., Nichols W.C., Rabinovitch M., Rodman D.M., Stevens T., Tuder R.M., Voelkel N.F., Gail D.B. Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop. Circulation 2004, 109(24):2947-2952.
33. Ramos K.S.C.E.A.D. Toxic responses of the heart and vascular systems. Casarett & Doull's Toxicology: the Basic Science of Poisons 1996, 487-527. McGraw-Hill, New York. C.D. Klaassen (Ed.).
34. Rossouw J.E. Coronary heart disease in menopausal women: implications of primary and secondary prevention trials of hormones. Maturitas 2005, 51(1):51-63.
35. Sakao S., Tatsumi K., Voelkel N.F. Endothelial cells and pulmonary arterial hypertension: apoptosis, proliferation, interaction and transdifferentiation. Respiratory Research 2009, 10:95.
36. Selimovic N., Bergh C.H., Andersson B., Sakiniene E., Carlsten H., Rundqvist B. Growth factors and interleukin-6 across the lung circulation in pulmonary hypertension. European Respiratory Journal 2009, 34(3):662-668.
37. Sergeev A.V., Carpenter D.O. Hospitalization rates for coronary heart disease in relation to residence near areas contaminated with persistent organic pollutants and other pollutants. Environmental Health Perspectives 2005, 113(6):756-761.
38. Tavolari S., Bucci L., Tomasi V., Guarnieri T. Selected polychlorobiphenyls congeners bind to estrogen receptor alpha in human umbilical vascular endothelial (HUVE) cells modulating angiogenesis. Toxicology 2006, 218(1):67-74.
39. Tokunaga S., Kataoka K. A longitudinal analysis on the association of serum lipids and lipoproteins concentrations with blood polychlorinated biphenyls level in chronic "Yusho" patients. Fukuoka Igaku Zasshi 2003, 94(5):110-117.
40. Venetsanakos E., Mirza A., Fanton C., Romanov S.R., Tlsty T., Mcmahon M. Induction of tubulogenesis in telomerase-immortalized human microvascular endothelial cells by glioblastoma cells. Experimental Cell Research 2002, 273(1):21-33.
41. Wassermann M., Wassermann D., Cucos S., Miller H.J. World PCBs map: storage and effects in man and his biologic environment in the 1970s. Annals of the New York Academy of Sciences 1979, 320:69-124.
42. Yang S.H., Liu R., Perez E.J., Wen Y., JR Stevens S.M., Valencia T., Brun-Zinkernagel A.M., Prokai L., Will Y., Dykens J., Koulen P., Simpkins J.W. Mitochondrial localization of estrogen receptor beta. Proceedings of the National Academy of Sciences of the United States of America 2004, 101(12):4130-4135.
43. Yoo C., Cooper G.F. An evaluation of a system that recommends microarray experiments to perform to discover gene-regulation pathways. Artificial Intelligence in Medicine 2004, 31(2):169-182.