Gli1 inhibition induces cell-cycle arrest and enhanced apoptosis in brain glioma cell lines

Journal of Neuro-Oncology

Volumn 98, Issue 3, 2010, Pages 319-327

  Wang, Ke ^a   Pan, Li ^a   Che, Xiaoming ^a   Cui, Daming ^a   Li, Chao ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Apoptosis; Bcl 2; Cell cycle; Cyclin D; Cyclin E; GLI; Glioma; Hedgehog; p21

Indexed keywords

CYCLOPAMINE; KI 67 ANTIGEN; PROTEIN BCL 2; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR GLI1;

ADULT; AGED; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE OVEREXPRESSION; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PROTEIN DEPLETION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; BRAIN NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FLOW CYTOMETRY; GLIOMA; HUMANS; KI-67 ANTIGEN; ONCOGENE PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIME FACTORS; TRANS-ACTIVATORS; TRANSFECTION; VERATRUM ALKALOIDS;

EID: 77953615901     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-009-0082-3     Document Type: Article

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