Activating Fgfr3 Y367C mutation causes hearing loss and inner ear defect in a mouse model of chondrodysplasia

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1792, Issue 2, 2009, Pages 140-147

  Pannier, Stéphanie ^a   Couloigner, Vincent ^a   Messaddeq, Nadia ^b   Elmaleh Bergès, Monique ^c   Munnich, Arnold ^a   Romand, Raymond ^b   Legeai Mallet, Laurence ^a  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

Chondrodysplasia; Cochlea; Fgfr3; Hearing loss; Pillar cell

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHONDRODYSPLASIA; CONTROLLED STUDY; CORTI ORGAN; EVOKED BRAIN STEM AUDITORY RESPONSE; GENE MUTATION; HAIR CELL; HEARING LOSS; IMMUNOPATHOLOGY; INNER EAR MALFORMATION; MOUSE; NONHUMAN; OSSIFICATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; THANATOPHORIC DWARFISM;

ANIMALS; CHONDRODYSPLASIA PUNCTATA; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; HEARING LOSS; HETEROZYGOTE; LABYRINTH DISEASES; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; MUTATION; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3; TYROSINE;

MUS;

EID: 58549087918     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2008.11.010     Document Type: Article

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