Twinkle and POLG defects enhance age-dependent accumulation of mutations in the control region of mtDNA

Nucleic Acids Research

Volumn 32, Issue 10, 2004, Pages 3053-3064

  Wanrooij, Sjoerd ^c   Luoma, Petri ^a   van Goethem, Gert ^b   van Broeckhoven, Christine ^b   Suomalainen, Anu ^a   Spelbrink, Johannes N ^c  

^a UNIVERSITY OF HELSINKI   (Finland)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; DNA DIRECTED DNA POLYMERASE GAMMA; HELICASE; MITOCHONDRIAL DNA; TWINKLE PROTEIN; UNCLASSIFIED DRUG; CYTOCHROME B; DNA DIRECTED DNA POLYMERASE; DNA PRIMASE; PEO1 PROTEIN, HUMAN; POLG PROTEIN, HUMAN;

AGE DISTRIBUTION; ARTICLE; AUTOSOMAL DOMINANT DISORDER; AUTOSOMAL RECESSIVE DISORDER; BASE MISPAIRING; CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA; CLINICAL ARTICLE; CONTROLLED STUDY; DNA REPLICATION; EXTRAOCULAR MUSCLE; FEMALE; GENE DELETION; HUMAN; HYPOTHESIS; MALE; MITOSIS; MUTAGENESIS; MUTATIONAL ANALYSIS; POINT MUTATION; PRIORITY JOURNAL; SKELETAL MUSCLE; ADULT; AGED; AGING; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PEDIGREE; PRESCHOOL CHILD; REGULATOR GENE;

ADULT; AGED; AGING; CHILD, PRESCHOOL; CYTOCHROMES B; DNA HELICASES; DNA PRIMASE; DNA REPLICATION; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; FEMALE; HUMANS; LOCUS CONTROL REGION; MALE; MIDDLE AGED; MUSCLE, SKELETAL; MUTAGENESIS; OPHTHALMOPLEGIA, CHRONIC PROGRESSIVE EXTERNAL; PEDIGREE; SEQUENCE DELETION;

EID: 2942672611     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh634     Document Type: Article

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