A sensitive and selective HPLC/ESI-MS/MS assay for the simultaneous quantification of 16-dehydropregnenolone and its major metabolites in rabbit plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 830, Issue 1, 2006, Pages 54-63

  Suryawanshi, Satyendra ^a   Singh, S K ^a   Gupta, R C ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

16 Dehydropregnenolone; Hypolipidaemic agent; LC MS MS; MRM; Rabbit plasma

Indexed keywords

ASSAYS; IONIZATION; MASS SPECTROMETRY; METABOLITES; PHARMACOKINETICS; PLASMAS; SENSITIVITY ANALYSIS;

16-DEHYDROPREGNENOLONE; HYPOLIPIDAEMIC AGENT; LC-MS-MS; MRM; RABBIT PLASMA;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

16 DEHYDROPREGNENOLONE; 4,16 PREGNADIEN 3,20 DIONE; 5 PREGNENE 3BETA OL 16,17 EPOXI 20 ONE; 5 PREGNENE 3BETA,20 DIOL; 5,16 PREGNADIEN 3BETA,11 DIOL 20 ONE; ACETONITRILE; AMMONIUM ACETATE; ANTILIPEMIC AGENT; DEXAMETHASONE; PREGNENOLONE; PREGNENOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; PLASMA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RABBIT; STANDARD;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; PREGNENOLONE; RABBITS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 29244465821     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.10.012     Document Type: Article

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