Design and synthesis of isonucleosides constructed on a 2-Oxa-6-thiabicyclo[3.2.0]heptane Scaffold (1)

Journal of Organic Chemistry

Volumn 75, Issue 12, 2010, Pages 4161-4171

  Yoshimura, Yuichi ^a   Asami, Kazuhiro ^a   Imamichi, Tomozumi ^b   Okuda, Tomoko ^c   Shiraki, Kimiyasu ^c   Takahata, Hiroki ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c UNIVERSITY OF TOYAMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DEPROTECTION; EPOXIDE GROUPS; LAMIVUDINE; MITSUNOBU REACTIONS; MODEL COMPOUND; NOVEL METHODS; NUCLEOBASES; THIOL DERIVATIVES; THIOPHENOLS; TRIFLUOROACETIC ACIDS;

DESULFURIZATION; FLUOROPHORES; HEPTANE; MERCURY (METAL); SCAFFOLDS;

SYNTHESIS (CHEMICAL);

2 OXA 6 THIABICYCLO[3.2.0]HEPTANE; 2,2 DIMETHYL 1,3 DIOXAN 5 ONE; HEPTANE DERIVATIVE; ISONUCLEOSIDE DERIVATIVE; KETONE DERIVATIVE; LAMIVUDINE; MESYLIC ACID; NUCLEIC ACID BASE; NUCLEOSIDE DERIVATIVE; THIOL; THIOPHENOL; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DESULFURIZATION; MIGRATION; MITSUNOBU REACTION; SYNTHESIS;

ALKANES; ANTI-HIV AGENTS; BICYCLO COMPOUNDS; DRUG DESIGN; LAMIVUDINE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEOSIDES; QUANTUM THEORY;

EID: 77953482280     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo100556u     Document Type: Article

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