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Volumn 2, Issue 4, 2009, Pages 207-213

Acacia senegal gum exudate offers protection against cyclophosphamide- induced urinary bladder cytotoxicity

Author keywords

Acrolein; Bladder inflammation; Cyclophosphamide; Gum arabic; Lipid peroxidation; Oxidative stress

Indexed keywords

ACETYLCHOLINE; CYCLOPHOSPHAMIDE; DRINKING WATER; GLUTATHIONE; GUM ARABIC; MALONALDEHYDE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE;

EID: 77953468282     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.4161/oxim.2.4.8878     Document Type: Article
Times cited : (49)

References (49)
  • 1
    • 0026100542 scopus 로고
    • Clinical pharmacokinetics of cyclophosphamide
    • Moore MJ. Clinical pharmacokinetics of cyclophosphamide. Clin Pharmacokinet 1991; 20:194-208.
    • (1991) Clin Pharmacokinet , vol.20 , pp. 194-208
    • Moore, M.J.1
  • 2
    • 0030694580 scopus 로고    scopus 로고
    • Induction of DNA crosslinks and DNA strand lesions by cyclophosphamide after activation by cytochrome P450 2B1
    • Hengstler JG, Hengst A, Fuchs J, Tanner B, Phol J, Oesch F. Induction of DNA crosslinks and DNA strand lesions by cyclophosphamide after activation by cytochrome P450 2B1. Mutat Res 1997; 373:215-23.
    • (1997) Mutat Res , vol.373 , pp. 215-223
    • Hengstler, J.G.1    Hengst, A.2    Fuchs, J.3    Tanner, B.4    Phol, J.5    Oesch, F.6
  • 3
    • 0017704271 scopus 로고
    • Effect of N-acetylcysteine on some aspects of cyclophosphamide induced toxicity and immuno-suppression
    • Levy L, Harris R. Effect of N-acetylcysteine on some aspects of cyclophosphamide induced toxicity and immuno-suppression. Biochem Pharmacol 1977; 26:1015-20.
    • (1977) Biochem Pharmacol , vol.26 , pp. 1015-1020
    • Levy, L.1    Harris, R.2
  • 4
    • 0018749594 scopus 로고
    • Cyclophosphamide-cystitis identification of acrolein as the causative agent
    • Cox Pj. Cyclophosphamide-cystitis identification of acrolein as the causative agent. Biochem Pharmacol 1977; 28:2045-9.
    • (1977) Biochem Pharmacol , vol.28 , pp. 2045-2049
    • Cox, P.1
  • 6
    • 0026411104 scopus 로고
    • Cyclophosphamide toxicity characterizing and avoiding problem
    • Fraiser LH, Kanekal S, Kehrer JP. Cyclophosphamide toxicity characterizing and avoiding problem. Drugs 1991; 42:781-95.
    • (1991) Drugs , vol.42 , pp. 781-795
    • Fraiser, L.H.1    Kanekal, S.2    Kehrer, J.P.3
  • 8
    • 0026499284 scopus 로고
    • Murine strain differences in metabolism and bladder toxicity of cyclophosphamide
    • Fraiser LH, Kehrer JP. Murine strain differences in metabolism and bladder toxicity of cyclophosphamide. Toxicology 1992; 7:255-72.
    • (1992) Toxicology , vol.7 , pp. 255-272
    • Fraiser, L.H.1    Kehrer, J.P.2
  • 10
    • 0033775712 scopus 로고    scopus 로고
    • Nitric oxide and NK1-Tachkinin receptors in cyclophosphamide-induced cystitis in rats
    • Alfieri AB, Cubeddu LX. Nitric oxide and NK1-Tachkinin receptors in cyclophosphamide-induced cystitis in rats. J Pharmacol Exper Ther 2000; 295:824-9.
    • (2000) J Pharmacol Exper Ther , vol.295 , pp. 824-829
    • Alfieri, A.B.1    Cubeddu, L.X.2
  • 11
    • 0036744865 scopus 로고    scopus 로고
    • Protective effect of ascorbic acid on cyclophosphamide-induced testicular gametogenic and androgenic disorders in male rats
    • Das UB, Mallick M, Debnath JM, Ghosh D. Protective effect of ascorbic acid on cyclophosphamide-induced testicular gametogenic and androgenic disorders in male rats. Asian J Androl 2002; 4:201-7.
    • (2002) Asian J Androl , vol.4 , pp. 201-207
    • Das, U.B.1    Mallick, M.2    Debnath, J.M.3    Ghosh, D.4
  • 12
    • 0019453058 scopus 로고
    • Role of glutathione in the metabolism dependent toxicity and chemotherapy of cyclophosphamide
    • Gurtoo HL, Hipkens JH, Sharma SD. Role of glutathione in the metabolism dependent toxicity and chemotherapy of cyclophosphamide. Cancer Res 1981; 41:3584-91.
    • (1981) Cancer Res , vol.41 , pp. 3584-3591
    • Gurtoo, H.L.1    Hipkens, J.H.2    Sharma, S.D.3
  • 13
    • 0025968103 scopus 로고
    • Glutathione diminishes the anti-tumor activity of 4- hydroperoxycyclophosphamide by stabilizing its spontaneous breakdown to alkylating metabolites
    • Lee FYF. Glutathione diminishes the anti-tumor activity of 4-hydroperoxycyclophosphamide by stabilizing its spontaneous breakdown to alkylating metabolites. Br J Cancer 1991; 63:45-50.
    • (1991) Br J Cancer , vol.63 , pp. 45-50
    • Lee, F.Y.F.1
  • 14
    • 0029852202 scopus 로고    scopus 로고
    • Kinetics of the reaction of a potential chemopreventive agent, 2,6-dithiopurine and its major metabolite, 2,6-dithiouric acid, with multiple classes of electrophilic toxicants
    • Qing WG, Powell KL, MacLeod MC. Kinetics of the reaction of a potential chemopreventive agent, 2,6-dithiopurine and its major metabolite, 2,6-dithiouric acid, with multiple classes of electrophilic toxicants. Chem Res Toxicol 1996; 9:1298-304.
    • (1996) Chem Res Toxicol , vol.9 , pp. 1298-1304
    • Qing, W.G.1    Powell, K.L.2    MacLeod, M.C.3
  • 15
    • 0032536166 scopus 로고    scopus 로고
    • Mixed effects of 2,6-dithiopurine against cyclophosphamide mediated bladder and lung toxicity in mice
    • Datta K, Chin A, Ahmed T, Qing WG, Powell KL, Simhambhatla P, et al. Mixed effects of 2,6-dithiopurine against cyclophosphamide mediated bladder and lung toxicity in mice. Toxicology 1998; 125:1-11.
    • (1998) Toxicology , vol.125 , pp. 1-11
    • Datta, K.1    Chin, A.2    Ahmed, T.3    Qing, W.G.4    Powell, K.L.5    Simhambhatla, P.6
  • 17
    • 0022836992 scopus 로고
    • Prevention of urotoxic side effects by regional detoxification with increased selectivity of oxazophosphorine cytostatics
    • Brock N, Pohl J. Prevention of urotoxic side effects by regional detoxification with increased selectivity of oxazophosphorine cytostatics. IARC Sci Publ 1986; 78:269-79.
    • (1986) IARC Sci Publ , vol.78 , pp. 269-279
    • Brock, N.1    Pohl, J.2
  • 18
    • 0033509482 scopus 로고    scopus 로고
    • Protective effect of the antioxidant stobadine against cyclophosphamide and irradiation induced oxidative stress
    • Navarova J, Ujhazy E, Dubovicky M. Protective effect of the antioxidant stobadine against cyclophosphamide and irradiation induced oxidative stress. Gen Physiol Biophys 1999; 18:112-9.
    • (1999) Gen Physiol Biophys , vol.18 , pp. 112-119
    • Navarova, J.1    Ujhazy, E.2    Dubovicky, M.3
  • 20
    • 0036431085 scopus 로고    scopus 로고
    • Protective effects of oral arabic gum administration on gentamicin-induced nephrotoxicity in rats
    • Al-Majed AA, Mostafa AM, Al-Rikabi AC, Al-Shabanah OA. Protective effects of oral arabic gum administration on gentamicin-induced nephrotoxicity in rats. Pharmacol Res 2002; 46:445-51.
    • (2002) Pharmacol Res , vol.46 , pp. 445-451
    • Al-Majed, A.A.1    Mostafa, A.M.2    Al-Rikabi, A.C.3    Al-Shabanah, O.A.4
  • 22
    • 4043068562 scopus 로고    scopus 로고
    • Oral Arabic gum administration prevents carbon tetrachloride-induced hepatotoxicity in mice: A possible mechanism of protection
    • Al-Majed AA. Oral Arabic gum administration prevents carbon tetrachloride-induced hepatotoxicity in mice: A possible mechanism of protection. Res Commun Pharmacol Toxicol 2003; 8:35-48.
    • (2003) Res Commun Pharmacol Toxicol , vol.8 , pp. 35-48
    • Al-Majed, A.A.1
  • 23
    • 58149188170 scopus 로고    scopus 로고
    • Biological effects of Gum Arabic: A review of some recent research
    • Ali BH, Ziada A, Blunden G. Biological effects of Gum Arabic: A review of some recent research. Food Chem Toxicol 2009; 47:1-8.
    • (2009) Food Chem Toxicol , vol.47 , pp. 1-8
    • Ali, B.H.1    Ziada, A.2    Blunden, G.3
  • 24
    • 54349091169 scopus 로고    scopus 로고
    • New insights into the structural characteristics of the arabinogalactan-protein (AGP) fraction of gum arabic
    • Mahendran T, Williams PA, Phillips GO, Al-Assaf S, Baldwin TC. New insights into the structural characteristics of the arabinogalactan-protein (AGP) fraction of gum arabic. J Agric Food Chem 2008; 56:9269-76.
    • (2008) J Agric Food Chem , vol.56 , pp. 9269-9276
    • Mahendran, T.1    Williams, P.A.2    Phillips, G.O.3    Al-Assaf, S.4    Baldwin, T.C.5
  • 26
    • 9144242252 scopus 로고    scopus 로고
    • Modulation of small intestinal nitric oxide synthase by gum arabic
    • Rehman KU, Codipilly CN, Wapnir RA. Modulation of small intestinal nitric oxide synthase by gum arabic. Exp Biol Med 2004; 229:895-901.
    • (2004) Exp Biol Med , vol.229 , pp. 895-901
    • Rehman, K.U.1    Codipilly, C.N.2    Wapnir, R.A.3
  • 27
    • 1842429543 scopus 로고    scopus 로고
    • Does gum arabic have an antioxidant action in rat kidney?
    • Ali BH. Does gum arabic have an antioxidant action in rat kidney? Ren Fail 2004; 26:1-3.
    • (2004) Ren Fail , vol.26 , pp. 1-3
    • Ali, B.H.1
  • 28
    • 0036453422 scopus 로고    scopus 로고
    • Protective effect of arabic gum against cardiotoxicity induced by doxorubicin in mice: A possible mechanism of protection
    • Abd-Allah AR, Al-Majed AA, Mostafa AM, Al-Shabanah OA, Din AG, Nagi MN. Protective effect of arabic gum against cardiotoxicity induced by doxorubicin in mice: a possible mechanism of protection. J Biochem Mol Toxicol 2002; 16:254-9.
    • (2002) J Biochem Mol Toxicol , vol.16 , pp. 254-259
    • Abd-Allah, A.R.1    Al-Majed, A.A.2    Mostafa, A.M.3    Al-Shabanah, O.A.4    Din, A.G.5    Nagi, M.N.6
  • 29
    • 0029008311 scopus 로고
    • Acrolein mercapturates: Synthesis, characterization and assessment of their role in the bladder toxicity of cyclophosphamide
    • Ramu K, Fraiser LH, Mamiya B, Ahmed T, Kehrer JP. Acrolein mercapturates: synthesis, characterization and assessment of their role in the bladder toxicity of cyclophosphamide. Chem Res Toxicol 1995; 8:515-24.
    • (1995) Chem Res Toxicol , vol.8 , pp. 515-524
    • Ramu, K.1    Fraiser, L.H.2    Mamiya, B.3    Ahmed, T.4    Kehrer, J.P.5
  • 34
    • 0027892639 scopus 로고
    • Effect of combined treatment with interleukin-3 and interleukin-6 on 4-hydroperoxycyclophosphamide-induced programmed cell death of apoptosis in human myeloid leukemia cells
    • Bullock G, Tang C, Tourkina E, Ibrado AM, Lutzky J, Huang Y, et al. Effect of combined treatment with interleukin-3 and interleukin-6 on 4-hydroperoxycyclophosphamide-induced programmed cell death of apoptosis in human myeloid leukemia cells. Exp Hematol 1993; 21:1640-7.
    • (1993) Exp Hematol , vol.21 , pp. 1640-1647
    • Bullock, G.1    Tang, C.2    Tourkina, E.3    Ibrado, A.M.4    Lutzky, J.5    Huang, Y.6
  • 35
    • 0030694580 scopus 로고    scopus 로고
    • Induction of DNA crosslinks and DNA strand lesions by cyclophosphamide after activation by cytochrome P450 2B1
    • Hengstler JG, Hengst A, Fuchs J, Tanner B, Phol J, Oesch F. Induction of DNA crosslinks and DNA strand lesions by cyclophosphamide after activation by cytochrome P450 2B1. Mutat Res 1997; 373:215-23.
    • (1997) Mutat Res , vol.373 , pp. 215-223
    • Hengstler, J.G.1    Hengst, A.2    Fuchs, J.3    Tanner, B.4    Phol, J.5    Oesch, F.6
  • 37
    • 0036981222 scopus 로고    scopus 로고
    • Alleviation of cyclophosphamide-induced urotoxicity by naturally occurring sulphur compounds
    • Manesh C, Kuttan G. Alleviation of cyclophosphamide-induced urotoxicity by naturally occurring sulphur compounds. J Exp Clin Cancer Res 2002; 21:509-17.
    • (2002) J Exp Clin Cancer Res , vol.21 , pp. 509-517
    • Manesh, C.1    Kuttan, G.2
  • 38
    • 3142711446 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase inhibition in cyclophosphamide induced hemorrhagic cystitis in rats
    • Oter S, Korkmaz A, Oztas E, Yildirim I, Topal T, Bikgic H. Inducible nitric oxide synthase inhibition in cyclophosphamide induced hemorrhagic cystitis in rats. Ureol Res 2004; 32:185-9.
    • (2004) Ureol Res , vol.32 , pp. 185-189
    • Oter, S.1    Korkmaz, A.2    Oztas, E.3    Yildirim, I.4    Topal, T.5    Bikgic, H.6
  • 39
    • 0034962143 scopus 로고    scopus 로고
    • Proabsorptive action of gum Arabic: Regulation of nitric oxide metabolism in the basolateral potassium channel of the small intestine
    • Rehman K, Wingertzahn MA, Harper RG, Wapnir RA. Proabsorptive action of gum Arabic: regulation of nitric oxide metabolism in the basolateral potassium channel of the small intestine. J Ped Gast Nut 2001; 32:529-33.
    • (2001) J Ped Gast Nut , vol.32 , pp. 529-533
    • Rehman, K.1    Wingertzahn, M.A.2    Harper, R.G.3    Wapnir, R.A.4
  • 42
  • 43
    • 0346531639 scopus 로고
    • The importance of bulk in nutrition of guinea pig
    • Booth AN, Elvehjem CA, Hart EB. The importance of bulk in nutrition of guinea pig. J Nutr 1949; 37:263-8.
    • (1949) J Nutr , vol.37 , pp. 263-268
    • Booth, A.N.1    Elvehjem, C.A.2    Hart, E.B.3
  • 44
    • 0017831986 scopus 로고
    • Biochemical effects of chronically administered suspended agents on mitochondrial metabolism and hepatic mixed function oxidase in rats, mice and hamster
    • Bachmann E, Zbinden G. Biochemical effects of chronically administered suspended agents on mitochondrial metabolism and hepatic mixed function oxidase in rats, mice and hamster. Arch Toxicol Suppl 1978; 1:183-7.
    • (1978) Arch Toxicol Suppl , vol.1 , pp. 183-187
    • Bachmann, E.1    Zbinden, G.2
  • 45
    • 0035019158 scopus 로고    scopus 로고
    • Protective effect of Berberine on cyclophosphamide hemorrhagic cystitis in rats
    • Xu X, Malave A. Protective effect of Berberine on cyclophosphamide hemorrhagic cystitis in rats. Pharmacol Toxicol 2001; 88:232-7.
    • (2001) Pharmacol Toxicol , vol.88 , pp. 232-237
    • Xu, X.1    Malave, A.2
  • 46
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid
    • Ohkawa H, Ohish N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid. Anal Biochem 1979; 95:351-8.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohish, N.2    Yagi, K.3
  • 47
    • 3042934967 scopus 로고
    • Tissue sulfahydryl groups
    • Ellman GL. Tissue sulfahydryl groups. Arch Biochem Biophys 1959; 82:70-7.
    • (1959) Arch Biochem Biophys , vol.82 , pp. 70-77
    • Ellman, G.L.1
  • 48
    • 0032728074 scopus 로고    scopus 로고
    • Effect of intravesical nitric oxide therapy on cyclophosphamide-induced cystitis
    • Ozawa H, Chancellor MB, Jung SY, Yokoyama T, Fraser MO, Yu Y, et al. Effect of intravesical nitric oxide therapy on cyclophosphamide-induced cystitis. J Urol 1999; 162:2211-6.
    • (1999) J Urol , vol.162 , pp. 2211-2216
    • Ozawa, H.1    Chancellor, M.B.2    Jung, S.Y.3    Yokoyama, T.4    Fraser, M.O.5    Yu, Y.6
  • 49
    • 33746339525 scopus 로고    scopus 로고
    • Effect of amino-guanidine and melatonin on the response of isolated urinary bladder to acetylcholine in normal and diabetic rats
    • Mostafa AM, Nagi MN, Al-Shabanah OA, El-Kashef HA. Effect of amino-guanidine and melatonin on the response of isolated urinary bladder to acetylcholine in normal and diabetic rats. Med Sci Res 2000; 28:33-7.
    • (2000) Med Sci Res , vol.28 , pp. 33-37
    • Mostafa, A.M.1    Nagi, M.N.2    Al-Shabanah, O.A.3    El-Kashef, H.A.4


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