Kinetics of the reaction of a potential chemopreventive agent, 2,6- dithiopurine, and its major metabolite, 2,6-dithiouric acid, with multiple classes of electrophilic toxicants

Chemical Research in Toxicology

Volumn 9, Issue 8, 1996, Pages 1298-1304

  Qing, Wei Guo ^a,b   Powell, K Leslie ^a   MacLeod, Michael C ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,6 DIMERCAPTOPURINE; 2,6 DITHIOURIC ACID; 6 MERCAPTOPURINE DERIVATIVE; ACROLEIN; CISPLATIN; DIHYDROXYBENZO[A]PYRENE OXIDE; DIMETHYL SULFATE; ETHYLNITROSOUREA; MELPHALAN; METHYLNITRONITROSOGUANIDINE; METHYLNITROSOUREA; SCAVENGER; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGEN DNA INTERACTION; METABOLITE; PH;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ACROLEIN; ANTICARCINOGENIC AGENTS; CHEMISTRY, PHYSICAL; CISPLATIN; KINETICS; MELPHALAN; NITROSO COMPOUNDS; PURINES; TOXINS, BIOLOGICAL; URIC ACID;

EID: 0029852202     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx960088n     Document Type: Article

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