Human eosinophils recognize endogenous danger signal crystalline uric acid and produce proinflammatory cytokines mediated by autocrine ATP

Journal of Immunology

Volumn 184, Issue 11, 2010, Pages 6350-6358

  Kobayashi, Takehito ^a   Kouzaki, Hideaki ^a   Kita, Hirohito ^a  

^a MAYO GRADUATE SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOKINE; EOSINOPHIL PROTEIN X; FIBROBLAST GROWTH FACTOR; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PURINERGIC P2Y2 RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; URATE; URIC ACID; VASCULOTROPIN; PURINERGIC P2 RECEPTOR;

ARTICLE; CELL DEATH; CELL MIGRATION; CHRONIC INFLAMMATION; CONTROLLED STUDY; CRYSTAL; CYTOKINE PRODUCTION; EOSINOPHIL; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TISSUE INJURY; BIOSYNTHESIS; CELL SEPARATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOLOGY; METABOLISM; NEUTROPHIL CHEMOTAXIS;

ADENOSINE TRIPHOSPHATE; CELL SEPARATION; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EOSINOPHILS; FLOW CYTOMETRY; HUMANS; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION; URIC ACID;

EID: 77953459979     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902673     Document Type: Article

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