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Volumn 1, Issue 3, 2009, Pages 425-434

Immunosuppressive therapy for autoimmune inner ear disease

Author keywords

Autoimmunity; Corticosteroid; Hearing loss; Immunomodulation; Immunosuppression

Indexed keywords

ALDOSTERONE; AZATHIOPRINE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; DEXAMETHASONE; ETANERCEPT; FLUOROURACIL; INFLIXIMAB; KEYHOLE LIMPET HEMOCYANIN; METHOTREXATE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; PREDNISONE; TACROLIMUS; TUMOR NECROSIS FACTOR ALPHA;

EID: 77953458311     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/imt.09.12     Document Type: Review
Times cited : (43)

References (66)
  • 1
    • 0018662622 scopus 로고
    • Autoimmune sensorineural hearing loss
    • McCabe BF: Autoimmune sensorineural hearing loss. Ann. Otol. Rhinol. Laryngol. 88(5 Pt 1), 585-589 (1979).
    • (1979) Ann. Otol. Rhinol. Laryngol. , vol.88 , Issue.5 PART 1 , pp. 585-589
    • McCabe, B.F.1
  • 2
    • 0021154693 scopus 로고
    • Practical versus theoretical management of autoimmune inner ear disease
    • Hughes GB, Kinney SE, Barna BP, Calabrese LH: Practical versus theoretical management of autoimmune inner ear disease. Laryngoscope. 94(6), 758-767 (1984).
    • (1984) Laryngoscope. , vol.94 , Issue.6 , pp. 758-767
    • Hughes, G.B.1    Kinney, S.E.2    Barna, B.P.3    Calabrese, L.H.4
  • 3
    • 14244268729 scopus 로고    scopus 로고
    • Autoimmune sensorineural hearing loss: Clinical course and treatment outcome
    • Loveman DM, de Comarmond C, Cepero R, Baldwin DM: Autoimmune sensorineural hearing loss: clinical course and treatment outcome. Semin. Arthritis Rheum. 34(2), 538-543 (2004).
    • (2004) Semin. Arthritis Rheum. , vol.34 , Issue.2 , pp. 538-543
    • Loveman, D.M.1    De Comarmond, C.2    Cepero, R.3    Baldwin, D.M.4
  • 5
    • 0020681316 scopus 로고
    • Immunology of the inner ear: Response of the inner ear to antigen challenge
    • Harris JP: Immunology of the inner ear: response of the inner ear to antigen challenge. Otolaryngol. Head Neck Surg. 91(1), 18-32 (1983).
    • (1983) Otolaryngol. Head Neck Surg. , vol.91 , Issue.1 , pp. 18-32
    • Harris, J.P.1
  • 6
    • 0021274661 scopus 로고
    • Immunology of the inner ear: Evidence of local antibody production
    • Harris JP: Immunology of the inner ear: evidence of local antibody production. Ann. Otol. Rhinol. Laryngol. 93(2 Pt 1), 157-162 (1984).
    • (1984) Ann. Otol. Rhinol. Laryngol. , vol.93 , Issue.2 PART 1 , pp. 157-162
    • Harris, J.P.1
  • 7
    • 0023752628 scopus 로고
    • Analysis of immunocompetent cells following inner ear immunostimulation
    • Takahashi M, Harris JP: Analysis of immunocompetent cells following inner ear immunostimulation. Laryngoscope 98(10), 1133-1138 (1988). (Pubitemid 18244330)
    • (1988) Laryngoscope , vol.98 , Issue.10 , pp. 1133-1138
    • Takahashi, M.1    Harris, J.P.2
  • 8
    • 0034012370 scopus 로고    scopus 로고
    • Characterization of an experimentally induced inner ear immune response
    • Ma C, Billings P, Harris JP, Keithley EM: Characterization of an experimentally induced inner ear immune response. Laryngoscope 110(3 Pt 1), 451-456 (2000). (Pubitemid 30143693)
    • (2000) Laryngoscope , vol.110 , Issue.3 I , pp. 451-456
    • Ma, C.-L.1    Billings, P.2    Harris, J.P.3    Keithley, E.M.4
  • 10
    • 0024593909 scopus 로고
    • Autoimmune disease and cochlear pathology in the C3H/lpr strain mouse
    • Trune DR, Craven JP, Morton JI, Mitchell C: Autoimmune disease and cochlear pathology in the C3H/lpr strain mouse. Hear. Res. 38(1-2), 57-66 (1989
    • (1989) Hear. Res. , vol.38 , Issue.1-2 , pp. 57-66
    • Trune, D.R.1    Craven, J.P.2    Morton, J.I.3    Mitchell, C.4
  • 11
    • 0026660518 scopus 로고
    • MRL/MP-lpr/lpr mouse as a model of immune-induced sensorineural hearing loss
    • Early description of the MRL/lpr model of a 'secondary' form of autoimmune inner ear disease (AIED)
    • Kusakari C, Hozawa K, Koike S, Kyogoku M, Takasaka T: MRL/MP-lpr/lpr mouse as a model of immune-induced sensorineural hearing loss. Ann. Otol. Rhinol. Laryngol. Suppl. 157, 82-86 (1992). ■ Early description of the MRL/lpr model of a 'secondary' form of autoimmune inner ear disease (AIED).
    • (1992) Ann. Otol. Rhinol. Laryngol. , Issue.SUPPL. 157 , pp. 82-86
    • Kusakari, C.1    Hozawa, K.2    Koike, S.3    Kyogoku, M.4    Takasaka, T.5
  • 13
    • 0023119456 scopus 로고
    • Experimental autoimmune sensorineural hearing loss
    • Early description of the keyhole limpet hemocyanin (KLH) model of AIED, a model frequently used to test efficacy of therapeutic interventions
    • Harris JP: Experimental autoimmune sensorineural hearing loss. Laryngoscope 97(1), 63-76 (1987). ■ Early description of the keyhole limpet hemocyanin (KLH) model of AIED, a model frequently used to test efficacy of therapeutic interventions.
    • (1987) Laryngoscope , vol.97 , Issue.1 , pp. 63-76
    • Harris, J.P.1
  • 14
    • 0024576736 scopus 로고
    • Experimental autoimmune inner ear disease
    • Soliman AM: Experimental autoimmune inner ear disease. Laryngoscope 99(2), 188-193 (1989).
    • (1989) Laryngoscope , vol.99 , Issue.2 , pp. 188-193
    • Soliman, A.M.1
  • 15
    • 0026622017 scopus 로고
    • Spontaneous remission in experimental autoimmune labyrinthitis
    • Yamanobe S, Harris JP: Spontaneous remission in experimental autoimmune labyrinthitis. Ann. Otol. Rhinol. Laryngol. 101(12), 1007-1014 (1992).
    • (1992) Ann. Otol. Rhinol. Laryngol. , vol.101 , Issue.12 , pp. 1007-1014
    • Yamanobe, S.1    Harris, J.P.2
  • 16
    • 0032696077 scopus 로고    scopus 로고
    • Experimental autoimmune labyrinthitis induced by cell-mediated immune reaction
    • DOI 10.1080/00016489950180603
    • Tomiyama S, Jinnouchi K, Ikezono T, Pawankar R, Yagi T: Experimental autoimmune labyrinthitis induced by cell-mediated immune reaction. Acta Otolaryngol. 119(6), 665-670 (1999). (Pubitemid 29513777)
    • (1999) Acta Oto-Laryngologica , vol.119 , Issue.6 , pp. 665-670
    • Tomiyama, S.1    Jinnouchi, K.2    Ikezono, T.3    Pawankar, R.4    Yagi, T.5
  • 18
    • 0031590778 scopus 로고    scopus 로고
    • Induction of an inner-ear-specific autoreactive T-cell line for the diagnostic evaluation of an autoimmune disease of the inner ear
    • Gloddek B, Gloddek J, Arnold W: Induction of an inner-ear-specific autoreactive T-cell line for the diagnostic evaluation of an autoimmune disease of the inner ear. Ann. NY Acad. Sci. 830, 266-276 (1997).
    • (1997) Ann. NY Acad. Sci. , vol.830 , pp. 266-276
    • Gloddek, B.1    Gloddek, J.2    Arnold, W.3
  • 20
    • 2142822899 scopus 로고    scopus 로고
    • + T cells specific for inner ear peptides
    • Description of a model for primary AIED involving immunization of mice against cochlin, an abundantly expressed inner ear-specific protein
    • + T cells specific for inner ear peptides. J. Clin. Invest. 113(8), 1210-1217 (2004). ■ Description of a model for primary AIED involving immunization of mice against cochlin, an abundantly expressed inner ear-specific protein.
    • (2004) J. Clin. Invest. , vol.113 , Issue.8 , pp. 1210-1217
    • Solares, C.A.1    Edling, A.E.2    Johnson, J.M.3
  • 21
    • 0035953042 scopus 로고    scopus 로고
    • Identification of the protein product of the Coch gene (hereditary deafness gene) as the major component of bovine inner ear protein
    • Ikezono T, Omori A, Ichinose S, Pawankar R, Watanabe A, Yagi T: Identification of the protein product of the Coch gene (hereditary deafness gene) as the major component of bovine inner ear protein. Biochim. Biophys. Acta. 1535(3), 258-265 (2001).
    • (2001) Biochim. Biophys. Acta , vol.1535 , Issue.3 , pp. 258-265
    • Ikezono, T.1    Omori, A.2    Ichinose, S.3    Pawankar, R.4    Watanabe, A.5    Yagi, T.6
  • 22
    • 33645125425 scopus 로고    scopus 로고
    • Increased frequencies of cochlin-specific T cells in patients with autoimmune sensorineural hearing loss
    • Baek MJ, Park HM, Johnson JM et al.: Increased frequencies of cochlin-specific T cells in patients with autoimmune sensorineural hearing loss. J. Immunol. 177(6), 4203-4210 (2006).
    • (2006) J. Immunol. , vol.177 , Issue.6 , pp. 4203-4210
    • Baek, M.J.1    Park, H.M.2    Johnson, J.M.3
  • 23
    • 0032940385 scopus 로고    scopus 로고
    • Effects of immunosuppression on the development of cochlear disease in the MRL-Fas(lpr) mouse
    • Ruckenstein MJ, Sarwar A, Hu L, Shami H, Marion TN: Effects of immunosuppression on the development of cochlear disease in the MRL-Fas(lpr) mouse. Laryngoscope 109(4), 626-630 (1999). (Pubitemid 29165916)
    • (1999) Laryngoscope , vol.109 , Issue.4 , pp. 626-630
    • Ruckenstein, M.J.1    Sarwar, A.2    Hu, L.3    Shami, H.4    Marion, T.N.5
  • 24
    • 0032720522 scopus 로고    scopus 로고
    • Steroid treatment in young MRL.MpJ-Fas(lpr) autoimmune mice prevents cochlear dysfunction
    • Trune DR, Wobig RJ, Kempton JB, Hefeneider SH: Steroid treatment in young MRL.MpJ-Fas(lpr) autoimmune mice prevents cochlear dysfunction. Hear. Res. 137(1-2), 167-173 (1999).
    • (1999) Hear. Res. , vol.137 , Issue.1-2 , pp. 167-173
    • Trune, D.R.1    Wobig, R.J.2    Kempton, J.B.3    Hefeneider, S.H.4
  • 25
    • 0032701680 scopus 로고    scopus 로고
    • Steroid treatment improves cochlear function in the MRL.MpJ-Fas(lpr) autoimmune mouse
    • Therapeutic intervention study in the MRL/lpr mouse model of AIED with steroids
    • Trune DR, Wobig RJ, Kempton JB, Hefeneider SH: Steroid treatment improves cochlear function in the MRL.MpJ-Fas(lpr) autoimmune mouse. Hear. Res. 137(1-2), 160-166 (1999). ■ Therapeutic intervention study in the MRL/lpr mouse model of AIED with steroids.
    • (1999) Hear. Res. , vol.137 , Issue.1-2 , pp. 160-166
    • Trune, D.R.1    Wobig, R.J.2    Kempton, J.B.3    Hefeneider, S.H.4
  • 26
    • 0027527215 scopus 로고
    • Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands
    • Rupprecht R, Reul JM, van Steensel B et al.: Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands. Eur. J. Pharmacol. 247(2), 145-154 (1993).
    • (1993) Eur. J. Pharmacol. , vol.247 , Issue.2 , pp. 145-154
    • Rupprecht, R.1    Reul, J.M.2    Van Steensel, B.3
  • 27
    • 0033762268 scopus 로고    scopus 로고
    • Aldosterone (mineralocorticoid) equivalent to prednisolone (glucocorticoid) in reversing hearing loss in MRL/MpJ-Faslpr autoimmune mice
    • Trune DR, Kempton JB, Kessi M: Aldosterone (mineralocorticoid) equivalent to prednisolone (glucocorticoid) in reversing hearing loss in MRL/MpJ-Faslpr autoimmune mice. Laryngoscope 110(11), 1902-1906 (2000).
    • (2000) Laryngoscope , vol.110 , Issue.11 , pp. 1902-1906
    • Trune, D.R.1    Kempton, J.B.2    Kessi, M.3
  • 28
    • 32844454421 scopus 로고    scopus 로고
    • Mineralocorticoid receptor mediates glucocorticoid treatment effects in the autoimmune mouse ear
    • Trune DR, Kempton JB, Gross ND: Mineralocorticoid receptor mediates glucocorticoid treatment effects in the autoimmune mouse ear. Hear. Res. 212(1-2), 22-32 (2006).
    • (2006) Hear. Res. , vol.212 , Issue.1-2 , pp. 22-32
    • Trune, D.R.1    Kempton, J.B.2    Gross, N.D.3
  • 29
    • 0035032762 scopus 로고    scopus 로고
    • Aldosterone and prednisolone control of cochlear function in MRL/MpJ-Fas(lpr) autoimmune mice
    • Trune DR, Kempton JB: Aldosterone and prednisolone control of cochlear function in MRL/MpJ-Fas(lpr) autoimmune mice. Hear. Res. 155(1-2), 9-20 (2001).
    • (2001) Hear. Res. , vol.155 , Issue.1-2 , pp. 9-20
    • Trune, D.R.1    Kempton, J.B.2
  • 30
    • 34248204640 scopus 로고    scopus 로고
    • Recent advances of TNF-α antagonists in rheumatoid arthritis and chronic heart failure
    • Mousa SA, Goncharuk O, Miller D: Recent advances of TNF-α antagonists in rheumatoid arthritis and chronic heart failure. Expert Opin. Biol. Ther. 7(5), 617-625 (2007).
    • (2007) Expert Opin. Biol. Ther. , vol.7 , Issue.5 , pp. 617-625
    • Mousa, S.A.1    Goncharuk, O.2    Miller, D.3
  • 31
    • 0036730159 scopus 로고    scopus 로고
    • Tumor necrosis factor-α, an initiator, and etanercept, an inhibitor of cochlear inflammation
    • Satoh H, Firestein GS, Billings PB, HarrisJP, Keithley EM: Tumor necrosis factor-α, an initiator, and etanercept, an inhibitor of cochlear inflammation. Laryngoscope 112(9), 1627-1634 (2002). (Pubitemid 34977568)
    • (2002) Laryngoscope , vol.112 , Issue.9 , pp. 1627-1634
    • Satoh, H.1    Firestein, G.S.2    Billings, P.B.3    Harris, J.P.4    Keithley, E.M.5
  • 32
    • 0025827590 scopus 로고
    • A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity
    • Peppel K, Crawford D, Beutler B: A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity. J. Exp. Med. 174(6), 1483-1489 (1991).
    • (1991) J. Exp. Med. , vol.174 , Issue.6 , pp. 1483-1489
    • Peppel, K.1    Crawford, D.2    Beutler, B.3
  • 34
    • 0037260742 scopus 로고    scopus 로고
    • Blockage of immune-mediated inner ear damage by etanercept
    • Study in the KLH model of AIED describing the effect of a TNF-α inhibitor on inner ear damage, delivered both systemically and via intratympanic injections
    • Wang X, Truong T, Billings PB, Harris JP, Keithley EM: Blockage of immune-mediated inner ear damage by etanercept. Otol. Neurotol. 24(1), 52-57 (2003). ■■ Study in the KLH model of AIED describing the effect of a TNF-α inhibitor on inner ear damage, delivered both systemically and via intratympanic injections.
    • (2003) Otol. Neurotol. , vol.24 , Issue.1 , pp. 52-57
    • Wang, X.1    Truong, T.2    Billings, P.B.3    Harris, J.P.4    Keithley, E.M.5
  • 35
    • 33745508532 scopus 로고    scopus 로고
    • TNF-α blockers do not improve the hearing recovery obtained with glucocorticoid therapy in an autoimmune experimental labyrinthitis
    • Animal study in the KLH model of AIED comparing the efficacy of TNF-α blockers and glucocorticoids, demonstrating that the two treatments are equally therapeutic
    • Lobo D, Trinidad A, Garcia-Berrocal JR, Verdaguer JM, Ramirez-Camacho R: TNF-α blockers do not improve the hearing recovery obtained with glucocorticoid therapy in an autoimmune experimental labyrinthitis. Eur. Arch. Otorhinolaryngol. 263(7), 622-626 (2006). ■ Animal study in the KLH model of AIED comparing the efficacy of TNF-α blockers and glucocorticoids, demonstrating that the two treatments are equally therapeutic.
    • (2006) Eur. Arch. Otorhinolaryngol. , vol.263 , Issue.7 , pp. 622-626
    • Lobo, D.1    Trinidad, A.2    Garcia-Berrocal, J.R.3    Verdaguer, J.M.4    Ramirez-Camacho, R.5
  • 36
    • 0024337989 scopus 로고
    • Autoimmune inner ear disease: Therapy
    • McCabe BF: Autoimmune inner ear disease: therapy. Am. J. Otol. 10(3), 196-197 (1989).
    • (1989) Am. J. Otol. , vol.10 , Issue.3 , pp. 196-197
    • McCabe, B.F.1
  • 38
    • 0035995031 scopus 로고    scopus 로고
    • Immune-mediated hearing loss: Basic mechanisms and options for therapy
    • Comprehensive review of disease mechanism and treatment options
    • Ryan AF, Harris JP, Keithley EM: Immune-mediated hearing loss: basic mechanisms and options for therapy. Acta Otolaryngol. 548 (Suppl.), 38-43 (2002). ■ Comprehensive review of disease mechanism and treatment options.
    • (2002) Acta Otolaryngol. , vol.548 , Issue.SUPPL. , pp. 38-43
    • Ryan, A.F.1    Harris, J.P.2    Keithley, E.M.3
  • 41
    • 23944483940 scopus 로고    scopus 로고
    • Corticosteroid response and supporting cell antibody in autoimmune hearing loss
    • Zeitoun H, Beekman JG, Arts HA et al.: Corticosteroid response and supporting cell antibody in autoimmune hearing loss. Arch. Otolaryngol. Head Neck Surg. 131(8), 665-672 (2005).
    • (2005) Arch. Otolaryngol. Head Neck Surg. , vol.131 , Issue.8 , pp. 665-672
    • Zeitoun, H.1    Beekman, J.G.2    Arts, H.A.3
  • 42
  • 43
    • 0031025310 scopus 로고    scopus 로고
    • Methotrexate management of immune-mediated cochleovestibular disorders
    • DOI 10.1016/S0194-5998(97)70316-4
    • Sismanis A, Wise CM, Johnson GD: Methotrexate management of immune-mediated cochleovestibular disorders. Otolaryngol Head Neck Surg. 116(2), 146-152 (1997). (Pubitemid 27097536)
    • (1997) Otolaryngology - Head and Neck Surgery , vol.116 , Issue.2 , pp. 146-152
    • Sismanis, A.1    Wise, C.M.2    Johnson, G.D.3
  • 44
    • 84942480376 scopus 로고
    • Serum antibody to inner ear proteins in patients with progressive hearing loss. Correlation with disease activity and response to corticosteroid treatment
    • Moscicki RA, San Martin JE, Quintero CH, Rauch SD, Nadol JB Jr, Bloch KJ: Serum antibody to inner ear proteins in patients with progressive hearing loss. Correlation with disease activity and response to corticosteroid treatment. JAMA 272(8), 611-616 (1994).
    • (1994) JAMA , vol.272 , Issue.8 , pp. 611-616
    • Moscicki, R.A.1    San Martin, J.E.2    Quintero, C.H.3    Rauch, S.D.4    Nadol Jr., J.B.5    Bloch, K.J.6
  • 46
    • 0034798551 scopus 로고    scopus 로고
    • Open trial of methotrexate as treatment for autoimmune hearing loss
    • Matteson EL, Fabry DA, Facer GW et al.: Open trial of methotrexate as treatment for autoimmune hearing loss. Arthritis Rheum. 45(2), 146-150 (2001).
    • (2001) Arthritis Rheum. , vol.45 , Issue.2 , pp. 146-150
    • Matteson, E.L.1    Fabry, D.A.2    Facer, G.W.3
  • 47
    • 0035002507 scopus 로고    scopus 로고
    • Methotrexate in the management of immune mediated cochleovestibular disorders: Clinical experience with 53 patients
    • Salley LH,Jr, Grimm M, Sismanis A, Spencer RF, Wise CM: Methotrexate in the management of immune mediated cochleovesitibular disorders: clinical experience with 53 patients. J. Rheumatol. 28(5), 1037-1040 (2001). (Pubitemid 32422585)
    • (2001) Journal of Rheumatology , vol.28 , Issue.5 , pp. 1037-1040
    • Salley Jr., L.H.1    Grimm, M.2    Sismanis, A.3    Spencer, R.F.4    Wise, C.M.5
  • 48
    • 0141957208 scopus 로고    scopus 로고
    • Treatment of corticosteroid-responsive autoimmune inner ear disease with methotrexate: A randomized controlled trial
    • Randomized controlled trial of methotrexate in AIED
    • Harris JP, Weisman MH, Derebery JM et al.: Treatment of corticosteroid-responsive autoimmune inner ear disease with methotrexate: a randomized controlled trial. JAMA. 290(14), 1875-1883 (2003). ■■ Randomized controlled trial of methotrexate in AIED.
    • (2003) JAMA , vol.290 , Issue.14 , pp. 1875-1883
    • Harris, J.P.1    Weisman, M.H.2    Derebery, J.M.3
  • 49
    • 0034857692 scopus 로고    scopus 로고
    • Etanercept therapy for immune-mediated cochleovestibular disorders: Preliminary results in a pilot study
    • Rahman MU, Poe DS, Choi HK: Etanercept therapy for immune-mediated cochleovestibular disorders: preliminary results in a pilot study. Otol. Neurotol. 22(5), 619-624 (2001).
    • (2001) Otol. Neurotol. , vol.22 , Issue.5 , pp. 619-624
    • Rahman, M.U.1    Poe, D.S.2    Choi, H.K.3
  • 50
    • 20444401580 scopus 로고    scopus 로고
    • Etanercept therapy for immune-mediated cochleovestibular disorders: A multi-center, open-label, pilot study
    • Matteson EL, Choi HK, Poe DS et al.: Etanercept therapy for immune-mediated cochleovestibular disorders: a multi-center, open-label, pilot study. Arthritis Rheum. 53(3), 337-342 (2005).
    • (2005) Arthritis Rheum. , vol.53 , Issue.3 , pp. 337-342
    • Matteson, E.L.1    Choi, H.K.2    Poe, D.S.3
  • 51
    • 24944479993 scopus 로고    scopus 로고
    • Etanercept treatment for autoimmune inner ear disease: Results of a pilot placebo-controlled study
    • Cohen S, Shoup A, Weisman MH, Harris J: Etanercept treatment for autoimmune inner ear disease: results of a pilot placebo-controlled study. Otol. Neurotol. 26(5), 903-907 (2005).
    • (2005) Otol. Neurotol. , vol.26 , Issue.5 , pp. 903-907
    • Cohen, S.1    Shoup, A.2    Weisman, M.H.3    Harris, J.4
  • 53
    • 0027362081 scopus 로고
    • Azathioprine in combination with steroids in the treatment of autoimmune inner-ear disease
    • Saracaydin A, Katircioglu S, Katircioglu S, Karatay MC: Azathioprine in combination with steroids in the treatment of autoimmune inner-ear disease. J. Int. Med. Res. 21(4), 192-196 (1993).
    • (1993) J. Int. Med. Res. , vol.21 , Issue.4 , pp. 192-196
    • Saracaydin, A.1    Katircioglu, S.2    Katircioglu, S.3    Karatay, M.C.4
  • 54
    • 33846374683 scopus 로고    scopus 로고
    • Etanercept, a tumour necrosis factor α receptor antagonist, and methotrexate in acute sensorineural hearing loss
    • Street I, Jobanputra P, Proops DW: Etanercept, a tumour necrosis factor α receptor antagonist, and methotrexate in acute sensorineural hearing loss. J. Laryngol. Otol. 120(12), 1064-1066 (2006).
    • (2006) J. Laryngol. Otol. , vol.120 , Issue.12 , pp. 1064-1066
    • Street, I.1    Jobanputra, P.2    Proops, D.W.3
  • 55
    • 0030774707 scopus 로고    scopus 로고
    • Plasmapheresis in autoimmune inner ear disease: Long-term follow-up
    • Luetje CM, Berliner KI: Plasmapheresis in autoimmune inner ear disease: long-term follow-up. Am. J. Otol. 18(5), 572-576 (1997).
    • (1997) Am. J. Otol. , vol.18 , Issue.5 , pp. 572-576
    • Luetje, C.M.1    Berliner, K.I.2
  • 56
    • 0034927816 scopus 로고    scopus 로고
    • Clinical aspects of round window membrane permeability under normal and pathological conditions
    • Goycoolea MV: Clinical aspects of round window membrane permeability under normal and pathological conditions. Acta Otolaryngol. 121(4), 437-447 (2001).
    • (2001) Acta Otolaryngol. , vol.121 , Issue.4 , pp. 437-447
    • Goycoolea, M.V.1
  • 57
    • 0032974309 scopus 로고    scopus 로고
    • Corticosteroid pharmacokinetics in the inner ear fluids: An animal study followed by clinical application
    • Discussion of cochlear pharmacokinetics and intratympanic clinical application
    • Parnes LS, Sun AH, Freeman DJ: Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application. Laryngoscope 109(7 Pt 2), 1-17(1999). ■ Discussion of cochlear pharmacokinetics and intratympanic clinical application
    • (1999) Laryngoscope , vol.109 , Issue.7 PART 2 , pp. 1-17
    • Parnes, L.S.1    Sun, A.H.2    Freeman, D.J.3
  • 58
    • 0034085181 scopus 로고    scopus 로고
    • Dexamethasone pharmacokinetics in the inner ear: Comparison of route of administration and use of facilitating agents
    • Chandrasekhar SS, Rubinstein RY, Kwartler JA et al.: Dexamethasone pharmacokinetics in the inner ear: comparison of route of administration and use of facilitating agents. Otolaryngol Head Neck Surg. 122(4), 521-528 (2000).
    • (2000) Otolaryngol Head Neck Surg. , vol.122 , Issue.4 , pp. 521-528
    • Chandrasekhar, S.S.1    Rubinstein, R.Y.2    Kwartler, J.A.3
  • 59
    • 33644886891 scopus 로고    scopus 로고
    • Dexamethasone pharmacokinetics in guinea pig inner ear perilymph
    • Liu HJ, Dong MM, Chi FL: Dexamethasone pharmacokinetics in guinea pig inner ear perilymph. ORL J. Otorhinolaryngol. Relat. Spec. 68(2), 93-98 (2006).
    • (2006) ORL J. Otorhinolaryngol. Relat. Spec. , vol.68 , Issue.2 , pp. 93-98
    • Liu, H.J.1    Dong, M.M.2    Chi, F.L.3
  • 60
    • 42249089875 scopus 로고    scopus 로고
    • The pharmacokinetic profiles of dexamethasone and methylprednisolone concentration in perilymph and plasma following systemic and local administration
    • DOI 10.1080/00016480701558906, PII 782850201
    • Yang J, Wu H, Zhang P, Hou DM, Chen J, Zhang SG: The pharmacokinetic profiles of dexamethasone and methylprednisolone concentration in perilymph and plasma following systemic and local administration. Acta Otolaryngol. 128(5), 496-504 (2008). (Pubitemid 351550959)
    • (2008) Acta Oto-Laryngologica , vol.128 , Issue.5 , pp. 496-504
    • Yang, J.1    Wu, H.2    Zhang, P.3    Hou, D.-M.4    Chen, J.5    Zhang, S.-G.6
  • 61
    • 0033933194 scopus 로고    scopus 로고
    • Intratympanic immunosuppressives for prevention of immune-mediated sensorineural hearing loss
    • Yang GS, Song HT, Keithley EM, Harris JP: Intratympanic immunosuppressives for prevention of immune-mediated sensorineural hearing loss. Am. J. Otol. 21(4), 499-504 (2000).
    • (2000) Am. J. Otol. , vol.21 , Issue.4 , pp. 499-504
    • Yang, G.S.1    Song, H.T.2    Keithley, E.M.3    Harris, J.P.4
  • 62
    • 40349091580 scopus 로고    scopus 로고
    • AM-111 reduces hearing loss in a guinea pig model of acute labyrinthitis
    • DOI 10.1097/MLG.0b013e3181461f92, PII 0000553720071200000017
    • Barkdull GC, Hondarrague Y, Meyer T, Harris JP, Keithley EM: AM-111 reduces hearing loss in a guinea pig model of acute labyrinthitis. Laryngoscope 117(12), 2174-2182 (2007). (Pubitemid 351339593)
    • (2007) Laryngoscope , vol.117 , Issue.12 , pp. 2174-2182
    • Barkdull, G.C.1    Hondarrague, Y.2    Meyer, T.3    Harris, J.P.4    Keithley, E.M.5
  • 64
    • 33749019741 scopus 로고    scopus 로고
    • Alternatives to systemic steroid therapy for refractory immune-mediated inner ear disease: A physiopathologic approach
    • Garcia-Berrocal JR, Ibanez A, Rodriguez A et al.: Alternatives to systemic steroid therapy for refractory immune-mediated inner ear disease: a physiopathologic approach. Eur. Arch. Otorhinolaryngol. 263(11), 977-982 (2006).
    • (2006) Eur. Arch. Otorhinolaryngol. , vol.263 , Issue.11 , pp. 977-982
    • Garcia-Berrocal, J.R.1    Ibanez, A.2    Rodriguez, A.3
  • 65
    • 33750277793 scopus 로고    scopus 로고
    • Local perfusion of the tumor necrosis factor α blocker infliximab to the inner ear improves autoimmune neurosensory hearing loss
    • Pilot study on the use of the intratympanic TNF-α inhibitor infliximab in AIED
    • Van Wijk F, Staecker H, Keithley E, Lefebvre PP: Local perfusion of the tumor necrosis factor α blocker infliximab to the inner ear improves autoimmune neurosensory hearing loss. Audiol. Neurootol. 11(6), 357-365 (2006). ■ Pilot study on the use of the intratympanic TNF-α inhibitor infliximab in AIED.
    • (2006) Audiol. Neurootol. , vol.11 , Issue.6 , pp. 357-365
    • Van Wijk, F.1    Staecker, H.2    Keithley, E.3    Lefebvre, P.P.4
  • 66
    • 24944533928 scopus 로고    scopus 로고
    • Serial audiometry in a clinical trial of AIED treatment
    • Niparko JK, Wang NY, Rauch SD et al.: Serial audiometry in a clinical trial of AIED treatment. Otol. Neurotol. 26(5), 908-917 (2005).
    • (2005) Otol. Neurotol. , vol.26 , Issue.5 , pp. 908-917
    • Niparko, J.K.1    Wang, N.Y.2    Rauch, S.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.