Corticosteroid response and supporting cell antibody in autoimmune hearing loss

Archives of Otolaryngology - Head and Neck Surgery

Volumn 131, Issue 8, 2005, Pages 665-672

  Zeitoun, Hisham ^a,e   Beckman, Jennifer Gray ^b,f   Arts, H Alexander ^a   Lansford, Christopher D ^a,b   Lee, David S ^a,b,g   El Kashlan, Hussam K ^a   Telian, Steven A ^a   Denny, Dawn E ^b,h   Ramakrishnan, Anna ^b   Nair, Thankam S ^b   Disher, Michael J ^a,i   Sataloff, Robert T ^c   Fisher, Susan G ^d   Carey, Thomas E ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d UNIVERSITY OF ROCHESTER   (United States)

^e GLAN CLWYD HOSPITAL   (United Kingdom)

^f Finnegan Henderson Farabow Garrett and Dunner LLP   (United States)

^g Otolaryngology/Head and Neck Surgery Ltd   (United States)

^h MERCK RESEARCH LABORATORIES   (United States)

ⁱ Ear Nose and Throat Associates PC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ANTIBODY; CORTICOSTEROID;

ADOLESCENT; ADULT; AGED; ANTIGEN ANTIBODY REACTION; ARTICLE; AUDIOGRAPHY; AUDIOMETRY; AUTOIMMUNE DISEASE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; CORTICOSTEROID THERAPY; DRUG RESPONSE; FEMALE; FOLLOW UP; HEARING LOSS; HUMAN; IMMUNOFLUORESCENCE TEST; INNER EAR; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PATIENT SELECTION; PERCEPTION DEAFNESS; PROSPECTIVE STUDY; UNITED STATES; WESTERN BLOTTING;

ADULT; AGED; AUDIOMETRY; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNE DISEASES; BLOTTING, WESTERN; CHI-SQUARE DISTRIBUTION; FEMALE; GLUCOCORTICOIDS; HEARING LOSS, SENSORINEURAL; HUMANS; MALE; METHYLPREDNISOLONE; MIDDLE AGED; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 23944483940     PISSN: 08864470     EISSN: None     Source Type: Journal    
DOI: 10.1001/archotol.131.8.665     Document Type: Article

References (24)

1. McCabe BF. Autoimmune sensorineural hearing loss. Ann Otol Rhinol Laryngol. 1979;88:585-589.
2. Harris JP, Sharp PA. Inner ear autoantibodies in patients with rapidly progressive sensorineural hearing loss. Laryngoscope. 1990;100:516-524.
3. Hughes GB, Moscicki R, Barna BP, San Martin JE. Laboratory diagnosis of immune inner ear disease. Am J Otol. 1994;15:198-202.
4. Moscicki RA, San Martin JE, Quintero CH, Rauch SD, Nadol JB, Bloch KJ. Serum antibody to inner ear proteins in patients with progressive hearing loss: correlation with disease activity and response to corticosteroid treatment. JAMA. 1994;272:611-616.
5. Zajic G, Nair TS, Ptok M, et al. Monoclonal antibodies to inner ear antigens, I: antigens expressed by supporting cells of the guinea pig cochlea. Hear Res. 1991;52:59-71.
6. Nair TS, Raphael Y, Dolan DF, et al. Monoclonal antibody induced hearing loss. Hear Res. 1995;83:101-113.
7. Nair TS, Prieskorn DM, Miller JM, Mori A, Gray J, Carey TE. In vivo binding and hearing loss after intracochlear infusion of KHRI-3 antibody. Hear Res. 1997;107:93-101.
8. Disher MJ, Ramakrishnan A, Nair TS, et al. Human autoantibodies and monoclonal antibody KHRI-3 bind to a phylogenetically conserved inner-ear supporting cell antigen. Ann N Y Acad Sci. 1997;830:253-265.
9. Cao MY, Deggouj N, Gersdorff M, Tomasi JP. Guinea pig inner ear antigens: extraction and application to the study of human autoimmune inner ear disease. Laryngoscope. 1996;106:207-212.
10. Joliat T, Seyer J, Bernstein J, et al. Antibodies against a 30 kilodalton cochlear protein and type II and IX collagens in the serum of patients with inner ear diseases. Ann Otol Rhinol Laryngol. 1992;101:1000-1006.
11. Boulassel M-R, Tomasi J-P, Deggouj N, Gersdorff M. COCH5B2 is a target antigen of anti-inner ear antibodies in autoimmune inner ear diseases. Otol Neurotol. 2001;22:614-618.
12. Boulassel MR, Deggouj N, Tomasi JP, Gersdorff M. Inner ear autoantibodies and their targets in patients with autoimmune inner ear diseases. Acta Otolaryngol. 2001;121:28-34.
13. Yamanobe S, Harris JP. Inner ear-specific autoantibodies. Laryngoscope. 1993;103:319-325.
14. Gottschlich S, Billings PB, Keithley EM, Weisman MH, Harris JP. Assessment of serum antibodies in patients with rapidly progressive sensorineural hearing loss and Meniere's disease. Laryngoscope. 1995;105:1347-1352.
15. Harris JP, Ryan AF. Immunobiology of the inner ear. Am J Otolaryngol. 1984;5:418-425.
16. Bloch DB, San Martin JE, Rauch SD, Moscicki RA, Bloch KJ. Serum antibodies to heat shock protein 70 in sensorineural hearing loss. Arch Otolaryngol Head Neck Surg. 1995;121:1167-1171.
17. Shin S-O, Billings PB, Keithley EM, Harris JP. Comparison of anti-heat shock protein 70 (anti-hsp70) and anti-68-kDa inner ear protein in the sera of patients with Meniere's disease. Laryngoscope. 1997;107:222-227.
18. Hirose K, Wener MH, Duckert LG. Utility of laboratory testing in autoimmune inner ear disease. Laryngoscope. 1999;109:1749-1754.
19. Billings PB, Shin SO, Harris JP. Assessing the role of anti-HSP 70 in cochlear impairment. Hear Res. 1998;126:210-212.
20. Trune DR, Kempton BJ, Mitchell CR, Hefeneider SH. Failure of elevated heat shock protein 70 antibodies to alter cochlear function in mice. Hear Res. 1998;116:65-70.
21. Yeom K, Gray J, Nair TS, et al. Antibodies to HSP 70 in normal donors and autoimmune hearing loss patients. Laryngoscope. 2003;113:1770-1776.
22. Nair TS, Prieskorn DM, Garrett D, et al. KHRI-3 monoclonal antibody-induced damage to the inner ear: antibody staining of nascent scars. Hear Res. 1999;129:50-60.
23. Slattery WH, Fisher LM, Iqbal Z, Liu N. Oral steroid regimens for idiopathic sudden sensorineural hearing loss. Otolaryngol Head Neck Surg. 2005;132:5-10.
24. Nair TS, Kozma KE, Hoefling NL, et al. Identification and characterization of CTL2, an inner ear glycoprotein of 68 and 72 kDa that is the target of antibody-induced hearing loss. J Neurosci. 2004;24:1772-1779.