-
1
-
-
0030805622
-
A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
-
Alam Z.I., Daniel S.E., Lees A.J., Marsden D.C., Jenner P., Halliwell B. A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J. Neurochem. 1997, 69:1326-1329.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1326-1329
-
-
Alam, Z.I.1
Daniel, S.E.2
Lees, A.J.3
Marsden, D.C.4
Jenner, P.5
Halliwell, B.6
-
2
-
-
34547807613
-
Global changes to the ubiquitin system in Huntington's disease
-
Bennett E.J., Shaler T.A., Woodman B., Ryu K.Y., Zaitseva T.S., Becker C.H., Bates G.P., Schulman H., Kopito R.R. Global changes to the ubiquitin system in Huntington's disease. Nature 2007, 448:704-708.
-
(2007)
Nature
, vol.448
, pp. 704-708
-
-
Bennett, E.J.1
Shaler, T.A.2
Woodman, B.3
Ryu, K.Y.4
Zaitseva, T.S.5
Becker, C.H.6
Bates, G.P.7
Schulman, H.8
Kopito, R.R.9
-
3
-
-
68749107083
-
Parkin promotes intracellular Abeta1-42 clearance
-
Burns M.P., Zhang L., Rebeck G.W., Querfurth H.W., Moussa C.E. Parkin promotes intracellular Abeta1-42 clearance. Hum. Mol. Genet. 2009, 18:3206-3216.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 3206-3216
-
-
Burns, M.P.1
Zhang, L.2
Rebeck, G.W.3
Querfurth, H.W.4
Moussa, C.E.5
-
4
-
-
0035879693
-
Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine
-
Castellani R.J., Harris P.L., Sayre L.M., Fujii J., Taniguchi N., Vitek M.P., Founds H., Atwood C.S., Perry G., Smith M.A. Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine. Free Radic. Biol. Med. 2001, 31:175-180.
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 175-180
-
-
Castellani, R.J.1
Harris, P.L.2
Sayre, L.M.3
Fujii, J.4
Taniguchi, N.5
Vitek, M.P.6
Founds, H.7
Atwood, C.S.8
Perry, G.9
Smith, M.A.10
-
5
-
-
38449083555
-
The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxias
-
Davies J.E., Sarkar S., Rubinsztein D.C. The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxias. BMC Biochem. 2007, 8(Suppl. 1):S2.
-
(2007)
BMC Biochem.
, vol.8
, Issue.SUPPL. 1
-
-
Davies, J.E.1
Sarkar, S.2
Rubinsztein, D.C.3
-
6
-
-
0030977793
-
Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein
-
Friguet B., Szweda L.I. Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein. FEBS Lett. 1997, 405:21-25.
-
(1997)
FEBS Lett.
, vol.405
, pp. 21-25
-
-
Friguet, B.1
Szweda, L.I.2
-
7
-
-
0029611219
-
Ubiquitin-positive degenerating neurites in the brainstem in Parkinson's disease
-
Gai W.P., Blessing W.W., Blumbergs P.C. Ubiquitin-positive degenerating neurites in the brainstem in Parkinson's disease. Brain 1995, 118(Pt 6):1447-1459.
-
(1995)
Brain
, vol.118
, Issue.PART 6
, pp. 1447-1459
-
-
Gai, W.P.1
Blessing, W.W.2
Blumbergs, P.C.3
-
8
-
-
34249679116
-
P62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis
-
Gal J., Strom A.L., Kilty R., Zhang F., Zhu H. p62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis. J. Biol. Chem. 2007, 282:11068-11077.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 11068-11077
-
-
Gal, J.1
Strom, A.L.2
Kilty, R.3
Zhang, F.4
Zhu, H.5
-
9
-
-
25144472262
-
Phospho-beta-catenin accumulation in Alzheimer's disease and in aggresomes attributable to proteasome dysfunction
-
Ghanevati M., Miller C.A. Phospho-beta-catenin accumulation in Alzheimer's disease and in aggresomes attributable to proteasome dysfunction. J. Mol. Neurosci. 2005, 25:79-94.
-
(2005)
J. Mol. Neurosci.
, vol.25
, pp. 79-94
-
-
Ghanevati, M.1
Miller, C.A.2
-
10
-
-
0031939204
-
Protein nitration in Parkinson's disease
-
Good P.F., Hsu A., Werner P., Perl D.P., Olanow C.W. Protein nitration in Parkinson's disease. J. Neuropathol. Exp. Neurol. 1998, 57:338-342.
-
(1998)
J. Neuropathol. Exp. Neurol.
, vol.57
, pp. 338-342
-
-
Good, P.F.1
Hsu, A.2
Werner, P.3
Perl, D.P.4
Olanow, C.W.5
-
11
-
-
0032080117
-
Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome
-
Grune T., Blasig I.E., Sitte N., Roloff B., Haseloff R., Davies K.J. Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome. J. Biol. Chem. 1998, 273:10857-10862.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10857-10862
-
-
Grune, T.1
Blasig, I.E.2
Sitte, N.3
Roloff, B.4
Haseloff, R.5
Davies, K.J.6
-
12
-
-
0030982143
-
Degradation of oxidized proteins in mammalian cells
-
Grune T., Reinheckel T., Davies K.J. Degradation of oxidized proteins in mammalian cells. FASEB J. 1997, 11:526-534.
-
(1997)
FASEB J.
, vol.11
, pp. 526-534
-
-
Grune, T.1
Reinheckel, T.2
Davies, K.J.3
-
13
-
-
0034796353
-
Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment
-
Halliwell B. Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Aging 2001, 18:685-716.
-
(2001)
Drugs Aging
, vol.18
, pp. 685-716
-
-
Halliwell, B.1
-
14
-
-
0003536299
-
-
Oxford University Press, Oxford/New York, [858] p. of plates
-
Halliwell B., Gutteridge J.M.C. Free Radicals in Biology and Medicine 2007, Oxford University Press, Oxford/New York, xxxvi, 851 p., [858] p. of plates.
-
(2007)
Free Radicals in Biology and Medicine
, vol.36
, pp. 851
-
-
Halliwell, B.1
Gutteridge, J.M.C.2
-
15
-
-
18544400489
-
Impaired clearance of oxidised proteins in neurodegenerative diseases
-
Halliwell B., Jenner P. Impaired clearance of oxidised proteins in neurodegenerative diseases. Lancet 1998, 351:1510.
-
(1998)
Lancet
, vol.351
, pp. 1510
-
-
Halliwell, B.1
Jenner, P.2
-
16
-
-
0033830826
-
Expression of heat shock protein 47(Hsp47) mRNA levels in rabbit connective tissues during the response to injury and in pregnancy
-
Hart D.A., Reno C., Hellio Le Graverand M.P., Hoffman L., Kulyk W. Expression of heat shock protein 47(Hsp47) mRNA levels in rabbit connective tissues during the response to injury and in pregnancy. Biochem. Cell Biol. 2000, 78:511-518.
-
(2000)
Biochem. Cell Biol.
, vol.78
, pp. 511-518
-
-
Hart, D.A.1
Reno, C.2
Hellio Le Graverand, M.P.3
Hoffman, L.4
Kulyk, W.5
-
18
-
-
0017064979
-
A fluorometric method for determination of oxidized and reduced glutathione in tissues
-
Hissin P.J., Hilf R. A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem. 1976, 74:214-226.
-
(1976)
Anal. Biochem.
, vol.74
, pp. 214-226
-
-
Hissin, P.J.1
Hilf, R.2
-
19
-
-
3142661740
-
Interference with ubiquitination causes oxidative damage and increased protein nitration: implications for neurodegenerative diseases
-
Hyun D.H., Gray D.A., Halliwell B., Jenner P. Interference with ubiquitination causes oxidative damage and increased protein nitration: implications for neurodegenerative diseases. J. Neurochem. 2004, 90:422-430.
-
(2004)
J. Neurochem.
, vol.90
, pp. 422-430
-
-
Hyun, D.H.1
Gray, D.A.2
Halliwell, B.3
Jenner, P.4
-
20
-
-
27844554819
-
Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults
-
Hyun D.H., Lee M., Halliwell B., Jenner P. Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults. J. Neurosci. Res. 2005, 82:232-244.
-
(2005)
J. Neurosci. Res.
, vol.82
, pp. 232-244
-
-
Hyun, D.H.1
Lee, M.2
Halliwell, B.3
Jenner, P.4
-
21
-
-
0036796753
-
Proteasomal dysfunction induced by 4-hydroxy-2,3-trans-nonenal, an end-product of lipid peroxidation: a mechanism contributing to neurodegeneration?
-
Hyun D.H., Lee M.H., Halliwell B., Jenner P. Proteasomal dysfunction induced by 4-hydroxy-2,3-trans-nonenal, an end-product of lipid peroxidation: a mechanism contributing to neurodegeneration?. J. Neurochem. 2002, 83:360-370.
-
(2002)
J. Neurochem.
, vol.83
, pp. 360-370
-
-
Hyun, D.H.1
Lee, M.H.2
Halliwell, B.3
Jenner, P.4
-
22
-
-
0038155130
-
Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins
-
Hyun D.H., Lee M., Halliwell B., Jenner P. Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins. J. Neurochem. 2003, 86:363-373.
-
(2003)
J. Neurochem.
, vol.86
, pp. 363-373
-
-
Hyun, D.H.1
Lee, M.2
Halliwell, B.3
Jenner, P.4
-
23
-
-
0035118930
-
Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defences: relevance to Down's syndrome and familial amyotrophic lateral sclerosis
-
Lee M., Hyun D., Jenner P., Halliwell B. Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defences: relevance to Down's syndrome and familial amyotrophic lateral sclerosis. J. Neurochem. 2001, 76:957-965.
-
(2001)
J. Neurochem.
, vol.76
, pp. 957-965
-
-
Lee, M.1
Hyun, D.2
Jenner, P.3
Halliwell, B.4
-
24
-
-
0034946830
-
Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production
-
Lee M.H., Hyun D.H., Jenner P., Halliwell B. Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production. J. Neurochem. 2001, 78:32-41.
-
(2001)
J. Neurochem.
, vol.78
, pp. 32-41
-
-
Lee, M.H.1
Hyun, D.H.2
Jenner, P.3
Halliwell, B.4
-
25
-
-
0034667727
-
Defective ubiquitination of cerebral proteins in Alzheimer's disease
-
Lopez Salon M., Morelli L., Castano E.M., Soto E.F., Pasquini J.M. Defective ubiquitination of cerebral proteins in Alzheimer's disease. J. Neurosci. Res. 2000, 62:302-310.
-
(2000)
J. Neurosci. Res.
, vol.62
, pp. 302-310
-
-
Lopez Salon, M.1
Morelli, L.2
Castano, E.M.3
Soto, E.F.4
Pasquini, J.M.5
-
26
-
-
0026362270
-
The role of protein ubiquitination in neurodegenerative disease
-
Mayer R.J., Lowe J., Landon M., McDermott H., Laszlo L. The role of protein ubiquitination in neurodegenerative disease. Acta Biol. Hung. 1991, 42:21-26.
-
(1991)
Acta Biol. Hung.
, vol.42
, pp. 21-26
-
-
Mayer, R.J.1
Lowe, J.2
Landon, M.3
McDermott, H.4
Laszlo, L.5
-
27
-
-
0035228702
-
Glial cells and abnormal protein handling in the pathogenesis of Parkinson's disease
-
McNaught K.S., Lee M., Hyun D.H., Jenner P. Glial cells and abnormal protein handling in the pathogenesis of Parkinson's disease. Adv. Neurol. 2001, 86:73-82.
-
(2001)
Adv. Neurol.
, vol.86
, pp. 73-82
-
-
McNaught, K.S.1
Lee, M.2
Hyun, D.H.3
Jenner, P.4
-
28
-
-
0035430788
-
Failure of the ubiquitin-proteasome system in Parkinson's disease
-
McNaught K.S., Olanow C.W., Halliwell B., Isacson O., Jenner P. Failure of the ubiquitin-proteasome system in Parkinson's disease. Nat. Rev. Neurosci. 2001, 2:589-594.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 589-594
-
-
McNaught, K.S.1
Olanow, C.W.2
Halliwell, B.3
Isacson, O.4
Jenner, P.5
-
29
-
-
0033559462
-
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease
-
Nunomura A., Perry G., Pappolla M.A., Wade R., Hirai K., Chiba S., Smith M.A. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J. Neurosci. 1999, 19:1959-1964.
-
(1999)
J. Neurosci.
, vol.19
, pp. 1959-1964
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
Wade, R.4
Hirai, K.5
Chiba, S.6
Smith, M.A.7
-
30
-
-
0033588087
-
4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules
-
Okada K., Wangpoengtrakul C., Osawa T., Toyokuni S., Tanaka K., Uchida K. 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules. J. Biol. Chem. 1999, 274:23787-23793.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23787-23793
-
-
Okada, K.1
Wangpoengtrakul, C.2
Osawa, T.3
Toyokuni, S.4
Tanaka, K.5
Uchida, K.6
-
31
-
-
0034884622
-
Proteasomal inhibition leads to formation of ubiquitin/alpha-synuclein-immunoreactive inclusions in PC12 cells
-
Rideout H.J., Larsen K.E., Sulzer D., Stefanis L. Proteasomal inhibition leads to formation of ubiquitin/alpha-synuclein-immunoreactive inclusions in PC12 cells. J. Neurochem. 2001, 78:899-908.
-
(2001)
J. Neurochem.
, vol.78
, pp. 899-908
-
-
Rideout, H.J.1
Larsen, K.E.2
Sulzer, D.3
Stefanis, L.4
-
32
-
-
0033964859
-
In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals
-
Sayre L.M., Perry G., Harris P.L., Liu Y., Schubert K.A., Smith M.A. In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals. J. Neurochem. 2000, 74:270-279.
-
(2000)
J. Neurochem.
, vol.74
, pp. 270-279
-
-
Sayre, L.M.1
Perry, G.2
Harris, P.L.3
Liu, Y.4
Schubert, K.A.5
Smith, M.A.6
-
33
-
-
0346386580
-
Widespread peroxynitrite-mediated damage in Alzheimer's disease
-
Smith M.A., Richey Harris P.L., Sayre L.M., Beckman J.S., Perry G. Widespread peroxynitrite-mediated damage in Alzheimer's disease. J. Neurosci. 1997, 17:2653-2657.
-
(1997)
J. Neurosci.
, vol.17
, pp. 2653-2657
-
-
Smith, M.A.1
Richey Harris, P.L.2
Sayre, L.M.3
Beckman, J.S.4
Perry, G.5
-
34
-
-
0029007478
-
Carbonyl-related posttranslational modification of neurofilament protein in the neurofibrillary pathology of Alzheimer's disease
-
Smith M.A., Rudnicka-Nawrot M., Richey P.L., Praprotnik D., Mulvihill P., Miller C.A., Sayre L.M., Perry G. Carbonyl-related posttranslational modification of neurofilament protein in the neurofibrillary pathology of Alzheimer's disease. J. Neurochem. 1995, 64:2660-2666.
-
(1995)
J. Neurochem.
, vol.64
, pp. 2660-2666
-
-
Smith, M.A.1
Rudnicka-Nawrot, M.2
Richey, P.L.3
Praprotnik, D.4
Mulvihill, P.5
Miller, C.A.6
Sayre, L.M.7
Perry, G.8
-
35
-
-
0034663360
-
Proteolytic degradation of tyrosine nitrated proteins
-
Souza J.M., Choi I., Chen Q., Weisse M., Daikhin E., Yudkoff M., Obin M., Ara J., Horwitz J., Ischiropoulos H. Proteolytic degradation of tyrosine nitrated proteins. Arch. Biochem. Biophys. 2000, 380:360-366.
-
(2000)
Arch. Biochem. Biophys.
, vol.380
, pp. 360-366
-
-
Souza, J.M.1
Choi, I.2
Chen, Q.3
Weisse, M.4
Daikhin, E.5
Yudkoff, M.6
Obin, M.7
Ara, J.8
Horwitz, J.9
Ischiropoulos, H.10
-
36
-
-
0034716979
-
Chaperone-like activity of synucleins
-
Souza J.M., Giasson B.I., Lee V.M., Ischiropoulos H. Chaperone-like activity of synucleins. FEBS Lett. 2000, 474:116-119.
-
(2000)
FEBS Lett.
, vol.474
, pp. 116-119
-
-
Souza, J.M.1
Giasson, B.I.2
Lee, V.M.3
Ischiropoulos, H.4
-
37
-
-
0035043251
-
Iron accumulation in the substantia nigra of autosomal recessive juvenile parkinsonism (ARJP)
-
Takanashi M., Mochizuki H., Yokomizo K., Hattori N., Mori H., Yamamura Y., Mizuno Y. Iron accumulation in the substantia nigra of autosomal recessive juvenile parkinsonism (ARJP). Parkinsonism Relat. Disord. 2001, 7:311-314.
-
(2001)
Parkinsonism Relat. Disord.
, vol.7
, pp. 311-314
-
-
Takanashi, M.1
Mochizuki, H.2
Yokomizo, K.3
Hattori, N.4
Mori, H.5
Yamamura, Y.6
Mizuno, Y.7
-
38
-
-
34548738343
-
Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration
-
Tan Z., Sun X., Hou F.S., Oh H.W., Hilgenberg L.G., Hol E.M., van Leeuwen F.W., Smith M.A., O'Dowd D.K., Schreiber S.S. Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration. Cell Death Differ. 2007, 14:1721-1732.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1721-1732
-
-
Tan, Z.1
Sun, X.2
Hou, F.S.3
Oh, H.W.4
Hilgenberg, L.G.5
Hol, E.M.6
van Leeuwen, F.W.7
Smith, M.A.8
O'Dowd, D.K.9
Schreiber, S.S.10
-
39
-
-
0035912730
-
Protein misfolding and temperature up-shift cause G1 arrest via a common mechanism dependent on heat shock factor in Saccharomyces cerevisiae
-
Trotter E.W., Berenfeld L., Krause S.A., Petsko G.A., Gray J.V. Protein misfolding and temperature up-shift cause G1 arrest via a common mechanism dependent on heat shock factor in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:7313-7318.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 7313-7318
-
-
Trotter, E.W.1
Berenfeld, L.2
Krause, S.A.3
Petsko, G.A.4
Gray, J.V.5
-
40
-
-
0035824651
-
Sensitivity of mammalian cells expressing mutant ubiquitin to protein-damaging agents
-
Tsirigotis M., Zhang M., Chiu R.K., Wouters B.G., Gray D.A. Sensitivity of mammalian cells expressing mutant ubiquitin to protein-damaging agents. J. Biol. Chem. 2001, 276:46073-46078.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46073-46078
-
-
Tsirigotis, M.1
Zhang, M.2
Chiu, R.K.3
Wouters, B.G.4
Gray, D.A.5
-
41
-
-
0033582784
-
Anti-oxidants prevent focal rat brain injury as assessed by induction of heat shock proteins (HSP70, HO-1/HSP32, HSP47) following subarachnoid injections of lysed blood
-
Turner C.P., Panter S.S., Sharp F.R. Anti-oxidants prevent focal rat brain injury as assessed by induction of heat shock proteins (HSP70, HO-1/HSP32, HSP47) following subarachnoid injections of lysed blood. Brain Res. Mol. Brain Res. 1999, 65:87-102.
-
(1999)
Brain Res. Mol. Brain Res.
, vol.65
, pp. 87-102
-
-
Turner, C.P.1
Panter, S.S.2
Sharp, F.R.3
-
42
-
-
0032867676
-
The 26S proteasome: a molecular machine designed for controlled proteolysis
-
Voges D., Zwickl P., Baumeister W. The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu. Rev. Biochem. 1999, 68:1015-1068.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 1015-1068
-
-
Voges, D.1
Zwickl, P.2
Baumeister, W.3
|