Iron accumulation in the substantia nigra of autosomal recessive juvenile parkinsonism (ARJP)

Parkinsonism and Related Disorders

Volumn 7, Issue 4, 2001, Pages 311-314

  Takanashi, Masashi ^a   Mochizuki, Hideki ^a   Yokomizo, Kazuko ^b   Hattori, Nobutaka ^a   Mori, Hideo ^a   Yamamura, Yasuhiro ^c   Mizuno, Yoshikuni ^a  

^a JUNTENDO UNIVERSITY   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Autosomal recessive juvenile parkinsonism (ARJP); Iron; Parkinson's disease (PD); Perls' stain

Indexed keywords

IRON; LEVODOPA;

ADULT; AGED; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CELL DEATH; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; HUMAN; HUMAN TISSUE; IRON STORAGE; LOCUS CERULEUS; MALE; NERVE DEGENERATION; NEURITE; OXIDATIVE STRESS; PARKINSONISM; PRIORITY JOURNAL; STAINING; SUBSTANTIA NIGRA;

EID: 0035043251     PISSN: 13538020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1353-8020(00)00050-X     Document Type: Article

References (11)

1. Mutations on the parkin gene cause autosomal recessive juvenile parkinsonism
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3. Is Parkinson's disease a progressive siderosis of substantia nigra in iron and melanin induced neurodegeneration?
4. The regional distribution and cellular localization of iron in the rat brain
5. Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q
6. Immunohistochemical and subcelluler localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients
7. Dopamine and DOPA cause release of iron from ferritin and lipid peroxidation of liposomes
8. Mitochondrial iron sequestration in dopamine-challenged astroglia: role of heme oxygenase-1 and the permeability transition pore
9. Neural heme oxygenase-1 expression in idiopathic Parkinson's disease
10. Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys
11. Familial Parkinson's disease gene product, parkin, is a ubiquitin-protein ligase