MAPK pathway mediates the protective effects of onychin on oxidative stress-induced apoptosis in ECV304 endothelial cells

Life Sciences

Volumn 76, Issue 5, 2004, Pages 487-497

  Tuo, Qin Hui ^a,b   Wang, Chun ^a   Yan, Feng Xiang ^a   Liao, Duan Fang ^a,b  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b Ctrl S Univ Xiangya Med College   (China)

Author keywords

apoptosis; ECV304; ERK1 2; Hydrogen Peroxide; Onychin; p38MAPK

Indexed keywords

CASPASE 3; GENISTEIN; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; ONYCHIN; PLANT EXTRACT; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL LINE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NICK END LABELING; OXIDATIVE STRESS; PROTEIN EXPRESSION; WESTERN BLOTTING;

ALKALOIDS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVANONES; FLOW CYTOMETRY; HUMANS; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; MAP KINASE SIGNALING SYSTEM; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTECTIVE AGENTS; PYRIDONES;

ORYCTOLAGUS CUNICULUS;

EID: 8844221260     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.03.042     Document Type: Article

References (27)

1. S. Dimmeler, C. Hermann, and A.M. Zeiher Apoptosis of endothelial cells. Contribution to the pathophysiology of atherosclerosis European Cytokine Network 9 4 1998 697 698
2. Y.G. Dong, D.D. Chen, J.G. He, and Y.Y. Guan Effects of 15-deoxy-delta12, 14-prostaglandin J2 on cell proliferation and apoptosis in ECV304 endothelial cells Acta Pharmacologica Sinica 25 1 2004 47 53
3. B. Edurne, T. Maria, Diaz-Meco, and M. Jorge The activation of p38 and apoptosis by the inhibition of Erk is antagonized by the phosphoinositide 3-kinase/Akt pathway The Journal of Biological Chemistry 273 1998 10792 10797
4. M.C. Gendron, N. Schrantz, D. Metivier, G. Kroemer, Z. Maciorowska, F. Sureau, S. Koester, and P.X. Petit Oxidation of pyridine nucleotides during Fas- and ceramide-induced apoptosis in Jurkat cells: correlation with changes in mitochondria, glutathione depletion, intracellular acidification and caspase 3 activation Biochemical Journal 353 2001 357 367
5. N. Gottstein, B.A. Ewins, C. Eccleston, G.P. Hubbard, I.C. Kavanagh, A.M. Minihane, P.D. Weinberg, and G. Rimbach Effect of genistein and daidzein on platelet aggregation and monocyte and endothelial function British Journal of Nutritional 89 5 2003 607 616
6. S. Kapiotis, M. Hermann, I. Held, C. Seelos, H. Ehringer, and B.M. Gmeiner Genistein, the dietary-derived angiogenesis inhibitor, prevents LDL oxidation and protects endothelial cells from damage by atherogenic LDL Arteriosclerosis, Thrombosis, and Vascular Biology 17 11 1997 2868 2874
7. K. Li, and X. Chen Protective effects of captopril and enalapril on myocardial ischemia and reperfusion damage of rat Journal of Molecular and Cellular Cardiology 19 9 1987 909 915
8. K. Li, D.J. Stewart, and J.L. Rouleau Myocardial contractile actions of endothelin-1 in rat and rabbit papillary muscles. Role of endocardial endothelium Circulation Research 69 2 1991 301 312
9. K. Li, J.L. Rouleau, L.J. Andries, and D.L. Brutsaert Effect of dysfunctional vascular endothelium on myocardial performance in isolated papillary muscles Circulation Research 72 4 1993 768 777
10. K. Li, P. Sirois, and J.L. Rouleau Role of endothelial cells in cardiovascular function Life Sciences 54 9 1994 579 592
11. K. Li, X. Qi, L. Andries, D. Stewart, P. Sirois, D. Brutsaert, and J.L. Rouleau Vascular-derived myocardial contractile factor: positive myocardial inotropic substance released from medial layer of the canine aorta Journal of Molecular and Cellular Cardiology 28 5 1996 881 892
12. D.F. Liao, B. Monia, N. Dean, and B.C. Berk Protein kinase C-zeta mediates angiotensin II activation of ERK1/2 in vascular smooth muscle cells The Journal of Biological Chemistry 272 10 1997 6146 6150
13. D.F. Liao, Z.G. Jin, A.S. Baas, G. Daum, S.P. Gygi, R. Aebersold, and B.C. Berk Purification and identification of secreted oxidative stress-induced factors from vascular smooth muscle cells The Journal of Biological Chemistry 275 1 2000 189 196
14. W.L. Liu, X. Guo, and Z.G. Guo Effects of p38 and p42/p44 CCDPK signaling on H2O2-induced apoptosis in bovine aortic endothelial cells Acta Pharmacologica Sinica 21 11 2000 991 996
15. W.L. Liu, X. Guo, Q.Q. Chen, and Z.G. Guo VEGF protects bovine aortic endothelial cells from TNF-alpha- and H2O2-induced apoptosis via co-modulatory effects on p38-and p42/p44-CCDPK signaling Acta Pharmacologica Sinica 23 1 2002 45 49
16. M.F. Melzig, and R. Loose Inhibition of lipopolysaccharide (LPS)-induced endothelial cytotoxicity by selected flavonoids Planta Medica 64 5 1998 397 399
17. V. Moreno-Manzano, Y. Ishikawa, J. Lucio-Cazana, and M. Kitamura Suppression of apoptosis by all-trans-retinoic acid. Dual intervention in the c-Jun n-terminal kinase-AP-1 pathway The Journal of Biological Chemistry 274 29 1999 20251 20258
18. K. Saeki, N. Kobayashi, Y. Inazawa, H. Zhang, H. Nishitoh, H. Ichijo, K. Saeki, M. Isemura, and A. Yuo Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis Biochemical Journal 368 2002 705 720
19. B. Sanna, M. Debidda, G. Pintus, B. Tadolini, A.M. Posadino, F. Bennardini, G. Sava, and C. Ventura The anti-metastatic agent imidazolium trans- imidazoledimethylsulfoxide -tetrachlororuthenate induces endothelial cell apoptosis by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway Archives of Biochemistry Biophysics 403 2 2002 209 218
20. D. Somjen, E. Knoll, F. Kohen, and N. Stern Effects of phytoestrogens on DNA synthesis and creatine kinase activity in vascular cells American Journal of Hypertension 14 12 2001 1256 1262
21. N. Takeyama, S. Miki, A. Hirakawa, and T. Tanaka Role of the mitochondrial permeability transition and cytochrome C release in hydrogen peroxide-induced apoptosis Experimental Cell Research 274 1 2002 16 24
22. H.J. Teede, B.P. McGrath, L. DeSilva, M. Cehun, A. Fassoulakis, and P.J. Nestel Isoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal women Arteriosclerosis, Thrombosis, and Vascular Biology 23 6 2003 1066 1071
23. O. Tricot, Z. Mallat, C. Heymes, J. Belmin, G. Leseche, and A. Tedgui Relation between endothelial cell apoptosis and blood flow direction in human atherosclerotic plaques Circulation 101 21 2000 2450 2453
24. Q.H. Tuo, H.L. Hang, Z.Z. Xie, and D.F. Liao Protection of onychin on injury of endothelium- dependent relaxation induced by lysophosphatidylcholine Chinese Journal of Arteriosclerosis 9 1 2001 27 30
25. Q.H. Tuo, D.F. Liao, and B.Y. Zhu Protective effects of onychin on vascular endothelial cell injured by oxidative stress Chinese Journal of Clinical Pharmacology and Therapeutics 8 2003 381 384
26. Y.L. Xu, X. Zheng, and Y.N. He Flavonoids of onychium lucidum Acta Botanica Yunnanica 21 3 1999 497 504
27. X. Zhang, K. Hu, and C.Y. Li Protection against oxidized low-density lipoprotein-induced vascular endothelial cell death by integrin-linked kinase Circulation 104 23 2001 2762 2766