Studies on two types of PTP1B inhibitors for the treatment of type 2 diabetes: Hologram QSAR for OBA and BBB analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 11, 2010, Pages 3329-3337

  Cheng, Yuanhua ^a   Zhou, Mei ^b   Tung, Chen Ho ^a   Ji, Mingjuan ^b   Zhang, Fushi ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

BBB; HQSAR; Inhibitors; OBA; PTP1B

Indexed keywords

2 (OXALYLAMINO)BENZOIC ACID; BENZOFURAN DERIVATIVE; BENZOIC ACID DERIVATIVE; BENZOTHIOPHENE DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG BINDING; DRUG STRUCTURE; IC 50; MOLECULAR LIBRARY; MOLECULAR MODEL; NON INSULIN DEPENDENT DIABETES MELLITUS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SCREENING;

DIABETES MELLITUS, TYPE 2; ENZYME INHIBITORS; MODELS, MOLECULAR; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77953285912     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.04.033     Document Type: Article

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