3D-QSAR analyses of novel benzofuranyl and benzothiophenyl biphenyls as PTP1B inhibitors

Chinese Journal of Organic Chemistry

Volumn 23, Issue 2, 2003, Pages 167-172

  Pan, Yong Mei ^a   Ji, Ming Juan ^a   Ye, Xue Qi ^a   Kuang, Ping Xian ^a  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

CoMFA; Inhibitor; Protein tyrosine phosphatases (PTPs); PTP1B

Indexed keywords

BENZOFURAN DERIVATIVE; BENZOTHIOPHENE DERIVATIVE; BIPHENYL DERIVATIVE; HYDROGEN; PROTEIN TYROSINE PHOSPHATASE INHIBITOR;

ARTICLE; DRUG ACTIVITY; ELECTRIC FIELD; ENZYME INHIBITION; HYDROGEN BOND; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

EID: 0037329257     PISSN: 02532786     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Zhang, Z. Y. Curr. Opin. Chem. Biol. 2001, 5, 416.
2. Goldstein, B. J. J. Cell. Biochem. 1992, 31, 33.
3. Goldstein, B. J. Receptor 1993, 3, 1.
4. Defronzo, R. A.; Bonadonna, R. C.; Ferrannini, E. Diabetes Care 1992, 15, 318.
5. Malamas, M. S.; Sredy, J.; Moxham, C.; Katz, A.; Xu, W.; McDevitt, R.; Adebayo, F. O.; Sawicki, D. R.; Seestaller, L.; Sullivan, D.; Taylor, J. R. J. Med. Chem. 2000, 43, 1293.
6. Cramer, R. D.; Patterson, D. E.; Bunce, J. D. J. Am. Chem. Soc. 1988, 110, 5959.
7. Hou, T.-J.; Xu, X.-J. Prog. Chem. 2001, 13, 436 (in Chinese).
8. Klebe, G.; Abraham, U.; Mietzner, T. J. Med. Chem. 1994, 37, 4130.
9. Tripos 6. 5 Users Guide, Tripos Inc., St. Louis, U. S. A., 1995.
10. Halgern, T. A. J. Comput. Chem. 1996, 17, 490.
11. Zhu, L.-L.; Hou, T.-J.; Xu, X.-J. Acta Chim. Sinica 2001, 59, 877 (in Chinese).
12. Hou, T.-J.; Li, Z.-M.; Li, Z.; Liu, J.; Xu, X.-J. J. Chem. Inf. Comp. Sci. 2000, 40, 1002.
13. Zhu, L.-L.; Hou, T.-J.; Xu, X.-J. J. Chem. Info. Comp. Sci. 2001, 41, 1032.
14. Hou, T.-J.; Xu, X.-J. Chemom. Intell. Lab. Syst. 2001, 56, 123.