메뉴 건너뛰기




Volumn 38, Issue 9, 2010, Pages 2904-2916

Human RECQL5β stimulates flap endonuclease 1

Author keywords

[No Author keywords available]

Indexed keywords

FLAP ENDONUCLEASE; FLAP ENDONUCLEASE 1; PROTEIN RECQL5 BETA; RECQ HELICASE; UNCLASSIFIED DRUG; DNA; RECQL5 PROTEIN, HUMAN; SINGLE STRANDED DNA;

EID: 77953250133     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp1217     Document Type: Article
Times cited : (20)

References (58)
  • 1
    • 0031663505 scopus 로고    scopus 로고
    • The DNA replication fork in eukaryotic cells
    • Waga, S. and Stillman, B. (1998) The DNA replication fork in eukaryotic cells. Annu. Rev. Biochem., 67, 721-751.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 721-751
    • Waga, S.1    Stillman, B.2
  • 3
    • 0032143062 scopus 로고    scopus 로고
    • Unraveling the role of helicases in transcription
    • Eisen, A. and Lucchesi, J.C. (1998) Unraveling the role of helicases in transcription. Bioessays, 20, 634-641.
    • (1998) Bioessays , vol.20 , pp. 634-641
    • Eisen, A.1    Lucchesi, J.C.2
  • 5
    • 0037364415 scopus 로고    scopus 로고
    • RecQ helicases: caretakers of the genome
    • Hickson, I.D. (2003) RecQ helicases: caretakers of the genome. Nat. Rev. Cancer, 3, 169-178.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 169-178
    • Hickson, I.D.1
  • 6
    • 0141567744 scopus 로고    scopus 로고
    • RecQ helicases: suppressors of tumorigenesis and premature aging
    • Bachrati, C.Z. and Hickson, I.D. (2003) RecQ helicases: suppressors of tumorigenesis and premature aging. Biochem. J., 374, 577-606.
    • (2003) Biochem. J. , vol.374 , pp. 577-606
    • Bachrati, C.Z.1    Hickson, I.D.2
  • 8
    • 0034737004 scopus 로고    scopus 로고
    • Rothmund-Thomson syndrome due to RECQ4 helicase mutations: report and clinical and molecular comparisons with Bloom syndrome and Werner syndrome
    • Lindor, N.M., Furuichi, Y., Kitao, S., Shimamoto, A., Arndt, C. and Jalal, S. (2000) Rothmund-Thomson syndrome due to RECQ4 helicase mutations: report and clinical and molecular comparisons with Bloom syndrome and Werner syndrome. Am. J. Med. Genet., 90, 223-228.
    • (2000) Am. J. Med. Genet. , vol.90 , pp. 223-228
    • Lindor, N.M.1    Furuichi, Y.2    Kitao, S.3    Shimamoto, A.4    Arndt, C.5    Jalal, S.6
  • 10
    • 0034164070 scopus 로고    scopus 로고
    • Human RecQ5β, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3α and 3β
    • Shimamoto, A., Nishikawa, K., Kitao, S. and Furuichi, Y. (2000) Human RecQ5β, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3α and 3β. Nucleic Acids Res., 28, 1647-1655.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 1647-1655
    • Shimamoto, A.1    Nishikawa, K.2    Kitao, S.3    Furuichi, Y.4
  • 11
    • 0037930738 scopus 로고    scopus 로고
    • Domain mapping of Escherichia coli RecQ defines the roles of conserved N-and C-terminal regions in the RecQ family
    • Bernstein, D.A. and Keck, J.L. (2003) Domain mapping of Escherichia coli RecQ defines the roles of conserved N-and C-terminal regions in the RecQ family. Nucleic Acids Res., 31, 2778-2785.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 2778-2785
    • Bernstein, D.A.1    Keck, J.L.2
  • 12
    • 3543007196 scopus 로고    scopus 로고
    • Human RECQ5β, a protein with DNA helicase and strand-annealing activities in a single polypeptide
    • Garcia, P.L., Liu, Y., Jiricny, J., West, S.C. and Janscak, P. (2004) Human RECQ5β, a protein with DNA helicase and strand-annealing activities in a single polypeptide. EMBO J., 23, 2882-2891.
    • (2004) EMBO J. , vol.23 , pp. 2882-2891
    • Garcia, P.L.1    Liu, Y.2    Jiricny, J.3    West, S.C.4    Janscak, P.5
  • 13
    • 45349089153 scopus 로고    scopus 로고
    • The zinc-binding motif of human RECQ5beta suppresses the intrinsic strand-annealing activity of its DExH helicase domain and is essential for the helicase activity of the enzyme
    • Ren, H., Dou, S.X., Zhang, X.D., Wang, P.Y., Kanagaraj, R., Liu, J.L., Janscak, P., Hu, J.S. and Xi, X.G. (2008) The zinc-binding motif of human RECQ5beta suppresses the intrinsic strand-annealing activity of its DExH helicase domain and is essential for the helicase activity of the enzyme. Biochem. J., 412, 425-433.
    • (2008) Biochem. J. , vol.412 , pp. 425-433
    • Ren, H.1    Dou, S.X.2    Zhang, X.D.3    Wang, P.Y.4    Kanagaraj, R.5    Liu, J.L.6    Janscak, P.7    Hu, J.S.8    Xi, X.G.9
  • 14
    • 33750980979 scopus 로고    scopus 로고
    • Human RECQ5β helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork
    • Kanagaraj, R., Saydam, N., Garcia, P.L., Zheng, L. and Janscak, P. (2006) Human RECQ5β helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork. Nucleic Acids Res., 34, 5217-5231.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 5217-5231
    • Kanagaraj, R.1    Saydam, N.2    Garcia, P.L.3    Zheng, L.4    Janscak, P.5
  • 15
    • 36849013079 scopus 로고    scopus 로고
    • RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments
    • Hu, Y., Raynard, S., Sehorn, M.G., Lu, X., Bussen, W., Zheng, L., Stark, J.M., Barnes, E.L., Chi, P., Janscak, P. et al. (2007) RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. Genes Dev., 21, 3073-3084.
    • (2007) Genes Dev. , vol.21 , pp. 3073-3084
    • Hu, Y.1    Raynard, S.2    Sehorn, M.G.3    Lu, X.4    Bussen, W.5    Zheng, L.6    Stark, J.M.7    Barnes, E.L.8    Chi, P.9    Janscak, P.10
  • 16
    • 39149114123 scopus 로고    scopus 로고
    • Analyses of functional interaction between RECQL1, RECQL5, and BLM which physically interact with DNA topoisomerase IIIalpha
    • Otsuki, M., Seki, M., Inoue, E., Abe, T., Narita, Y., Yoshimura, A., Tada, S., Ishii, Y. and Enomoto, T. (2008) Analyses of functional interaction between RECQL1, RECQL5, and BLM which physically interact with DNA topoisomerase IIIalpha. Biochim. Biophys. Acta, 1782, 75-81.
    • (2008) Biochim. Biophys. Acta , vol.1782 , pp. 75-81
    • Otsuki, M.1    Seki, M.2    Inoue, E.3    Abe, T.4    Narita, Y.5    Yoshimura, A.6    Tada, S.7    Ishii, Y.8    Enomoto, T.9
  • 17
    • 47249100637 scopus 로고    scopus 로고
    • A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin
    • Aygun, O., Svejstrup, J. and Liu, Y. (2008) A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin. Proc. Natl Acad. Sci. USA, 105, 8580-8584.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 8580-8584
    • Aygun, O.1    Svejstrup, J.2    Liu, Y.3
  • 19
    • 17644410077 scopus 로고    scopus 로고
    • Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers
    • Hu, Y., Lu, X., Barnes, E., Yan, M., Lou, H. and Luo, G. (2005) Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers. Mol. Cell Biol., 25, 3431-3442.
    • (2005) Mol. Cell Biol. , vol.25 , pp. 3431-3442
    • Hu, Y.1    Lu, X.2    Barnes, E.3    Yan, M.4    Lou, H.5    Luo, G.6
  • 20
    • 63049125856 scopus 로고    scopus 로고
    • Recql5 plays an important role in DNA replication and cell survival after camptothecin treatment
    • Hu, Y., Lu, X., Zhou, G., Barnes, E.L. and Luo, G. (2009) Recql5 plays an important role in DNA replication and cell survival after camptothecin treatment. Mol. Biol. Cell, 20, 114-123.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 114-123
    • Hu, Y.1    Lu, X.2    Zhou, G.3    Barnes, E.L.4    Luo, G.5
  • 21
    • 0028335180 scopus 로고
    • Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair
    • Harrington, J.J. and Lieber, M.R. (1994) Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair. Genes Dev., 8, 1344-1355.
    • (1994) Genes Dev. , vol.8 , pp. 1344-1355
    • Harrington, J.J.1    Lieber, M.R.2
  • 22
    • 0028089040 scopus 로고
    • The calf 5'-to3'-exonuclease is also an endonuclease with both activities dependent on primers annealed upstream of the point of cleavage
    • Murante, R.S., Huang, L., Turchi, J.J. and Bambara, R.A. (1994) The calf 5'-to3'-exonuclease is also an endonuclease with both activities dependent on primers annealed upstream of the point of cleavage. J. Biol. Chem., 269, 1191-1196.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1191-1196
    • Murante, R.S.1    Huang, L.2    Turchi, J.J.3    Bambara, R.A.4
  • 23
    • 0031104841 scopus 로고    scopus 로고
    • The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair
    • Lieber, M.R. (1997) The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair. Bioessays, 19, 233-240.
    • (1997) Bioessays , vol.19 , pp. 233-240
    • Lieber, M.R.1
  • 24
    • 3943086339 scopus 로고    scopus 로고
    • Flap endonuclease 1: a central component of DNA metabolism
    • Liu, Y., Kao, H.I. and Bambara, R.A. (2004) Flap endonuclease 1: a central component of DNA metabolism. Annu. Rev. Biochem., 73, 589-615.
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 589-615
    • Liu, Y.1    Kao, H.I.2    Bambara, R.A.3
  • 26
    • 0031054051 scopus 로고    scopus 로고
    • Enzymes and reactions at the eukaryotic DNA replication fork
    • Bambara, R.A., Murante, R.S. and Henricksen, L.A. (1997) Enzymes and reactions at the eukaryotic DNA replication fork. J. Biol. Chem., 272, 4647-4650.
    • (1997) J. Biol. Chem. , vol.272 , pp. 4647-4650
    • Bambara, R.A.1    Murante, R.S.2    Henricksen, L.A.3
  • 27
    • 0029063168 scopus 로고
    • Mutations in RAD27 define a potential link between G1 cyclins and DNA replication
    • Vallen, E.A. and Cross, F.R. (1995) Mutations in RAD27 define a potential link between G1 cyclins and DNA replication. Mol. Cell Biol., 15, 4291-4302.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 4291-4302
    • Vallen, E.A.1    Cross, F.R.2
  • 32
    • 0030957997 scopus 로고    scopus 로고
    • Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)
    • Klungland, A. and Lindahl, T. (1997) Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J., 16, 3341-3348.
    • (1997) EMBO J. , vol.16 , pp. 3341-3348
    • Klungland, A.1    Lindahl, T.2
  • 33
    • 0037016743 scopus 로고    scopus 로고
    • Defective flap endonuclease 1 activity in mammalian cells is associated with impaired DNA repair and prolonged S phase delay
    • Shibata, Y. and Nakamura, T. (2002) Defective flap endonuclease 1 activity in mammalian cells is associated with impaired DNA repair and prolonged S phase delay. J. Biol. Chem., 277, 746-754.
    • (2002) J. Biol. Chem. , vol.277 , pp. 746-754
    • Shibata, Y.1    Nakamura, T.2
  • 34
    • 0035980003 scopus 로고    scopus 로고
    • DNA polymerase b-mediated long patch base excision repair. Poly(ADP-ribose)polymerase-1 stimulates strand displacement DNA synthesis
    • Prasad, R., Lavrik, O.I., Kim, S.J., Kedar, P., Yang, X.P., Vande Berg, B.J. and Wilson, S.H. (2001) DNA polymerase b-mediated long patch base excision repair. Poly(ADP-ribose)polymerase-1 stimulates strand displacement DNA synthesis. J. Biol. Chem., 276, 32411-32414.
    • (2001) J. Biol. Chem. , vol.276 , pp. 32411-32414
    • Prasad, R.1    Lavrik, O.I.2    Kim, S.J.3    Kedar, P.4    Yang, X.P.5    Vande Berg, B.J.6    Wilson, S.H.7
  • 35
    • 0030018848 scopus 로고    scopus 로고
    • Specific interaction of DNA polymerase β and DNA ligase I in a multiprotein base excision repair complex from bovine testis
    • Prasad, R., Singhal, R.K., Srivastava, D.K., Molina, J.T., Tomkinson, A.E. and Wilson, S.H. (1996) Specific interaction of DNA polymerase β and DNA ligase I in a multiprotein base excision repair complex from bovine testis. J. Biol. Chem., 271, 16000-16007.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16000-16007
    • Prasad, R.1    Singhal, R.K.2    Srivastava, D.K.3    Molina, J.T.4    Tomkinson, A.E.5    Wilson, S.H.6
  • 36
    • 0035816708 scopus 로고    scopus 로고
    • Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair
    • Lavrik, O.I., Prasad, R., Sobol, R.W., Horton, J.K., Ackerman, E.J. and Wilson, S.H. (2001) Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair. J. Biol. Chem., 276, 25541-25548.
    • (2001) J. Biol. Chem. , vol.276 , pp. 25541-25548
    • Lavrik, O.I.1    Prasad, R.2    Sobol, R.W.3    Horton, J.K.4    Ackerman, E.J.5    Wilson, S.H.6
  • 37
    • 2342507720 scopus 로고    scopus 로고
    • AP endonuclease and poly(ADP-ribose) polymerase-1 interact with the same base excision repair intermediate
    • Cistulli, C., Lavrik, O.I., Prasad, R., Hou, E. and Wilson, S.H. (2004) AP endonuclease and poly(ADP-ribose) polymerase-1 interact with the same base excision repair intermediate. DNA Repair, 3, 581-591.
    • (2004) DNA Repair , vol.3 , pp. 581-591
    • Cistulli, C.1    Lavrik, O.I.2    Prasad, R.3    Hou, E.4    Wilson, S.H.5
  • 38
    • 0035940441 scopus 로고    scopus 로고
    • Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair
    • Dianova, II, Bohr, V.A. and Dianov, G.L. (2001) Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair. Biochemistry, 40, 12639-12644.
    • (2001) Biochemistry , vol.40 , pp. 12639-12644
    • Dianova, I.I.1    Bohr, V.A.2    Dianov, G.L.3
  • 39
    • 0036828697 scopus 로고    scopus 로고
    • AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair
    • Ranalli, T.A., Tom, S. and Bambara, R.A. (2002) AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair. J. Biol. Chem., 277, 41715-41724.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41715-41724
    • Ranalli, T.A.1    Tom, S.2    Bambara, R.A.3
  • 41
    • 0037044311 scopus 로고    scopus 로고
    • Biochemical characterization of the WRN-FEN-1 functional interaction
    • Brosh, R.M. Jr, Driscoll, H.C., Dianov, G.L. and Sommers, J.A. (2002) Biochemical characterization of the WRN-FEN-1 functional interaction. Biochemistry, 41, 12204-12216.
    • (2002) Biochemistry , vol.41 , pp. 12204-12216
    • Brosh R.M., Jr.1    Driscoll, H.C.2    Dianov, G.L.3    Sommers, J.A.4
  • 43
    • 0742288051 scopus 로고    scopus 로고
    • WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork
    • Sharma, S., Otterlei, M., Sommers, J.A., Driscoll, H.C., Dianov, G.L., Kao, H.I., Bambara, R.A. and Brosh, R.M. Jr (2004) WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork. Mol. Biol. Cell, 15, 734-750.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 734-750
    • Sharma, S.1    Otterlei, M.2    Sommers, J.A.3    Driscoll, H.C.4    Dianov, G.L.5    Kao, H.I.6    Bambara, R.A.7    Brosh R.M., Jr.8
  • 47
    • 0034616199 scopus 로고    scopus 로고
    • Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1
    • Tom, S., Henricksen, L.A. and Bambara, R.A. (2000) Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1. J. Biol. Chem., 275, 10498-10505.
    • (2000) J. Biol. Chem. , vol.275 , pp. 10498-10505
    • Tom, S.1    Henricksen, L.A.2    Bambara, R.A.3
  • 48
    • 0029885134 scopus 로고    scopus 로고
    • Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA
    • Wu, X., Li, J., Li, X., Hsieh, C.L., Burgers, P.M. and Lieber, M.R. (1996) Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA. Nucleic Acids Res., 24, 2036-2043.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2036-2043
    • Wu, X.1    Li, J.2    Li, X.3    Hsieh, C.L.4    Burgers, P.M.5    Lieber, M.R.6
  • 49
    • 0034595842 scopus 로고    scopus 로고
    • Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion
    • Henricksen, L.A., Tom, S., Liu, Y. and Bambara, R.A. (2000) Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion. J. Biol. Chem., 275, 16420-16427.
    • (2000) J. Biol. Chem. , vol.275 , pp. 16420-16427
    • Henricksen, L.A.1    Tom, S.2    Liu, Y.3    Bambara, R.A.4
  • 50
    • 23044449149 scopus 로고    scopus 로고
    • Multiple but dissectible functions of FEN-1 nucleases in nucleic acid processing, genome stability and diseases
    • Shen, B., Singh, P., Liu, R., Qiu, J., Zheng, L., Finger, L.D. and Alas, S. (2005) Multiple but dissectible functions of FEN-1 nucleases in nucleic acid processing, genome stability and diseases. Bioessays, 27, 717-729.
    • (2005) Bioessays , vol.27 , pp. 717-729
    • Shen, B.1    Singh, P.2    Liu, R.3    Qiu, J.4    Zheng, L.5    Finger, L.D.6    Alas, S.7
  • 51
    • 0032740855 scopus 로고    scopus 로고
    • RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coli
    • Courcelle, J. and Hanawalt, P.C. (1999) RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coli. Mol. Gen. Genet., 262, 543-551.
    • (1999) Mol. Gen. Genet. , vol.262 , pp. 543-551
    • Courcelle, J.1    Hanawalt, P.C.2
  • 53
    • 40649100251 scopus 로고    scopus 로고
    • Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways
    • Guo, Z., Chavez, V., Singh, P., Finger, L.D., Hang, H., Hegde, M.L. and Shen, B. (2008) Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways. J. Mol. Biol., 377, 679-690.
    • (2008) J. Mol. Biol. , vol.377 , pp. 679-690
    • Guo, Z.1    Chavez, V.2    Singh, P.3    Finger, L.D.4    Hang, H.5    Hegde, M.L.6    Shen, B.7
  • 54
    • 0032502675 scopus 로고    scopus 로고
    • Involvement of flap endonuclease 1 in base excision DNA repair
    • Kim, K., Biade, S. and Matsumoto, Y. (1998) Involvement of flap endonuclease 1 in base excision DNA repair. J. Biol. Chem., 273, 8842-8848.
    • (1998) J. Biol. Chem. , vol.273 , pp. 8842-8848
    • Kim, K.1    Biade, S.2    Matsumoto, Y.3
  • 55
    • 0033553510 scopus 로고    scopus 로고
    • Role of DNA polymerase beta in the excision step of long patch mammalian base excision repair
    • Dianov, G.L., Prasad, R., Wilson, S.H. and Bohr, V.A. (1999) Role of DNA polymerase beta in the excision step of long patch mammalian base excision repair. J. Biol. Chem., 274, 13741-13743.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13741-13743
    • Dianov, G.L.1    Prasad, R.2    Wilson, S.H.3    Bohr, V.A.4
  • 56
    • 13544261768 scopus 로고    scopus 로고
    • DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair
    • Liu, Y., Beard, W.A., Shock, D.D., Prasad, R., Hou, E.W. and Wilson, S.H. (2005) DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair. J. Biol. Chem., 280, 3665-3674.
    • (2005) J. Biol. Chem. , vol.280 , pp. 3665-3674
    • Liu, Y.1    Beard, W.A.2    Shock, D.D.3    Prasad, R.4    Hou, E.W.5    Wilson, S.H.6
  • 57
    • 0038681010 scopus 로고    scopus 로고
    • The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity
    • Harrigan, J.A., Opresko, P.L., von Kobbe, C., Kedar, P.S., Prasad, R., Wilson, S.H. and Bohr, V.A. (2003) The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity. J. Biol. Chem., 278, 22686-22695.
    • (2003) J. Biol. Chem. , vol.278 , pp. 22686-22695
    • Harrigan, J.A.1    Opresko, P.L.2    von Kobbe, C.3    Kedar, P.S.4    Prasad, R.5    Wilson, S.H.6    Bohr, V.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.