-
1
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
Balch, W.E., Morimoto, R.I., Dillin, A. & Kelly, J.F. Adapting proteostasis for disease intervention. Science 319, 916-919 (2008).
-
(2008)
Science
, vol.319
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.F.4
-
2
-
-
0037040541
-
Molecular chaperones in the cytosol: From nascent chain to folded protein
-
Hartl, F.U. & Hayer-Hartl, M. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295, 1852-1858 (2002).
-
(2002)
Science
, vol.295
, pp. 1852-1858
-
-
Hartl, F.U.1
Hayer-Hartl, M.2
-
3
-
-
33845978077
-
Snapshot: Molecular chaperone, part i
-
Chang, H.-C., Tang, Y.-C., Hayer-Hartl, M. & Hartl, F.U. Snapshot: molecular chaperone, part I. Cell 128, 212-213 (2007).
-
(2007)
Cell
, vol.128
, pp. 212-213
-
-
Chang, H.-C.1
Tang, Y.-C.2
Hayer-Hartl, M.3
Hartl, F.U.4
-
4
-
-
33846312878
-
Snapshot: Molecular chaper-ones, part II
-
Tang, Y.-C., Chang, H.-C., Hayer-Hartl, M. & Hartl, F.U. Snapshot: Molecular chaper-ones, part II. Cell 128, 412-413 (2007).
-
(2007)
Cell
, vol.128
, pp. 412-413
-
-
Tang, Y.-C.1
Chang, H.-C.2
Hayer-Hartl, M.3
Hartl, F.U.4
-
5
-
-
58149181486
-
Hsp104 and ClpB: Protein disaggregating machines
-
Doyle, S.M. & Wickner, S. Hsp104 and ClpB: protein disaggregating machines. Trends Biochem. Sci. 34, 40-48 (2009).
-
(2009)
Trends Biochem. Sci.
, vol.34
, pp. 40-48
-
-
Doyle, S.M.1
Wickner, S.2
-
6
-
-
34547455220
-
Collaboration between the ClpB AAA+ remodeling protein and the DnaK chaperone system
-
Doyle, S.M., Hoskins, J.R. & Wickner, S. Collaboration between the ClpB AAA+ remodeling protein and the DnaK chaperone system. Proc. Natl. Acad. Sci. USA 104, 11138-11144 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 11138-11144
-
-
Doyle, S.M.1
Hoskins, J.R.2
Wickner, S.3
-
7
-
-
0036809395
-
SecB, one small chaperone in the complex milieu of the cell
-
Randall, L.L. & Hardy, S.J.S. SecB, one small chaperone in the complex milieu of the cell. Cell. Mol. Life Sci. 59, 1617-1623 (2002).
-
(2002)
Cell. Mol. Life Sci.
, vol.59
, pp. 1617-1623
-
-
Randall, L.L.1
Hardy, S.J.S.2
-
8
-
-
60549101514
-
The cavity-chaperone Skp protects its substrate from aggregation but allows independent folding of substrate domains
-
Walton, T.A., Sandoval, C.M., Fowler, C.A., Pardi, A. & Sousa, M.C. The cavity-chaperone Skp protects its substrate from aggregation but allows independent folding of substrate domains. Proc. Natl. Acad. Sci. USA 106, 1772-1777 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 1772-1777
-
-
Walton, T.A.1
Sandoval, C.M.2
Fowler, C.A.3
Pardi, A.4
Sousa, M.C.5
-
9
-
-
33947218544
-
Identification of a targeting factor for posttranslational membrane protein insertion into the ER
-
Stefanovic, S. & Hegde, R.S. Identification of a targeting factor for posttranslational membrane protein insertion into the ER. Cell 128, 1147-1159 (2007).
-
(2007)
Cell
, vol.128
, pp. 1147-1159
-
-
Stefanovic, S.1
Hegde, R.S.2
-
10
-
-
0030021114
-
Cytoplasmic chaperones in precursor targeting to mitochondria: The role of MSF and hsp70
-
DOI 10.1016/0962-8924(96)81000-2
-
Mihara, K. & Omura, T. Cytoplasmic chaperones in precursor targeting to mitochondria: the role of MSF and hsp70. Trends Cell Biol. 6, 104-108 (1996). (Pubitemid 26059743)
-
(1996)
Trends in Cell Biology
, vol.6
, Issue.3
, pp. 104-108
-
-
Mihara, K.1
Omura, T.2
-
11
-
-
1642473879
-
Structure and function of the chloroplast signal recognition particle
-
Schuenemann, D. Structure and function of the chloroplast signal recognition particle. Curr. Genet. 44, 295-304 (2004).
-
(2004)
Curr. Genet.
, vol.44
, pp. 295-304
-
-
Schuenemann, D.1
-
12
-
-
0032544070
-
A novel signal recognition particle targets light-harvesting proteins to the thylakoid membranes
-
Schuenemann, D. et al. A novel signal recognition particle targets light-harvesting proteins to the thylakoid membranes. Proc. Natl. Acad. Sci. USA 95, 10312-10316 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10312-10316
-
-
Schuenemann, D.1
-
13
-
-
0035958865
-
Functional characterization of recombinant chloroplast signal recognition particle
-
Groves, M.R. et al. Functional characterization of recombinant chloroplast signal recognition particle. J. Biol. Chem. 276, 27778-27786 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27778-27786
-
-
Groves, M.R.1
-
14
-
-
0033578755
-
Chloroplast Ftsy chloroplast signal recognition particle, and GTP are required to reconstitute the soluble phase of light-harvesting chlorophyll protein transport into thylakoid membranes
-
Tu, C.-J., Schuenemann, D. & Hoffman, N.E. Chloroplast Ftsy, chloroplast signal recognition particle, and GTP are required to reconstitute the soluble phase of light-harvesting chlorophyll protein transport into thylakoid membranes. J. Biol. Chem. 274, 27219-27224 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27219-27224
-
-
Tu, C.-J.1
Schuenemann, D.2
Hoffman, N.E.3
-
15
-
-
6544282660
-
A chromodomain protein encoded by the Arabidopsis CAO gene is a plant-specific component of the chloroplast signal recognition particle pathway that is involved in LHCP targeting
-
Klimyuk, V.I. et al. A chromodomain protein encoded by the Arabidopsis CAO gene is a plant-specific component of the chloroplast signal recognition particle pathway that is involved in LHCP targeting. Plant Cell 11, 87-99 (1999).
-
(1999)
Plant Cell
, vol.11
, pp. 87-99
-
-
Klimyuk, V.I.1
-
16
-
-
0035852345
-
Function of a chloroplast SRP in thylakoid protein export
-
Eichacker, L.A. & Henry, R. Function of a chloroplast SRP in thylakoid protein export. Biochim. Biophys. Acta 1541, 120-134 (2001).
-
(2001)
Biochim. Biophys. Acta
, vol.1541
, pp. 120-134
-
-
Eichacker, L.A.1
Henry, R.2
-
17
-
-
0035816712
-
Functional analysis of the protein-interacting domains of chloroplast SRP43
-
Jonas-Straube, E., Hutin, C., Hoffman, N.E. & Schuenemann, D. Functional analysis of the protein-interacting domains of chloroplast SRP43. J. Biol. Chem. 276, 24654-24660 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24654-24660
-
-
Jonas-Straube, E.1
Hutin, C.2
Hoffman, N.E.3
Schuenemann, D.4
-
18
-
-
5644297077
-
Regulation of the GTPase cycle in post-translational signal recognition particle-based protein targeting involves cpSRP43
-
Goforth, R.L. et al. Regulation of the GTPase cycle in post-translational signal recognition particle-based protein targeting involves cpSRP43. J. Biol. Chem. 279, 43077-43084 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 43077-43084
-
-
Goforth, R.L.1
-
19
-
-
47249160767
-
Structural basis for specific substrate recognition by the chloroplast signal recognition particle protein cpSRP43
-
Stengel, K.F. et al. Structural basis for specific substrate recognition by the chloroplast signal recognition particle protein cpSRP43. Science 321, 253-256 (2008).
-
(2008)
Science
, vol.321
, pp. 253-256
-
-
Stengel, K.F.1
-
20
-
-
33646577139
-
The α-helix of the second chromodomain of the 43 kDa subunit of the chloroplast signal recognition particle facilitates binding to the 54 kDa subunit
-
Hermkes, R., Funke, S., Richter, C., Kuhlmann, J. & Schünemann, D. The α-helix of the second chromodomain of the 43 kDa subunit of the chloroplast signal recognition particle facilitates binding to the 54 kDa subunit. FEBS Lett. 580, 3107-3111 (2006).
-
(2006)
FEBS Lett.
, vol.580
, pp. 3107-3111
-
-
Hermkes, R.1
Funke, S.2
Richter, C.3
Kuhlmann, J.4
Schünemann, D.5
-
21
-
-
1642602038
-
Crystal structure of spinach major light-harvesting complex at 2.72 Å resolution
-
Liu, Z. et al. Crystal structure of spinach major light-harvesting complex at 2.72 Å resolution. Nature 428, 287-292 (2004).
-
(2004)
Nature
, vol.428
, pp. 287-292
-
-
Liu, Z.1
-
22
-
-
0026575756
-
In vitro reconstitution of a light-harvesting gene product: Deletion mutagenesis and analyses of pigment binding
-
Cammarata, K.V. & Schmidt, G.W. In vitro reconstitution of a light-harvesting gene product: deletion mutagenesis and analyses of pigment binding. Biochemistry 31, 2779-2789 (1992).
-
(1992)
Biochemistry
, vol.31
, pp. 2779-2789
-
-
Cammarata, K.V.1
Schmidt, G.W.2
-
23
-
-
0001456147
-
Reconstitution of pigment-containing complexes from light-harvesting chlorophyll a/b-binding protein overexpressed in Escherichia coli
-
Paulsen, H., Rumler, U. & Rudiger, W. Reconstitution of pigment-containing complexes from light-harvesting chlorophyll a/b-binding protein overexpressed in Escherichia coli. Planta 181, 204-211 (1990).
-
(1990)
Planta
, vol.181
, pp. 204-211
-
-
Paulsen, H.1
Rumler, U.2
Rudiger, W.3
-
24
-
-
0034652118
-
A novel precursor recognition element facilitates posttranslational binding to the signal recognition particle in chloroplasts
-
DeLille, J. et al. A novel precursor recognition element facilitates posttranslational binding to the signal recognition particle in chloroplasts. Proc. Natl. Acad. Sci. USA 97, 1926-1931 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1926-1931
-
-
Delille, J.1
-
25
-
-
0000580602
-
The L18 domain of light-harvesting chlorophyll proteins binds to chloroplast signal recognition particle 43
-
Tu, C.J., Peterson, E.C., Henry, R. & Hoffman, N.E. The L18 domain of light-harvesting chlorophyll proteins binds to chloroplast signal recognition particle 43. J. Biol. Chem. 275, 13187-13190 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13187-13190
-
-
Tu, C.J.1
Peterson, E.C.2
Henry, R.3
Hoffman, N.E.4
-
26
-
-
38049094411
-
Policing Tic 'n' Toc the doorway to chloroplasts
-
Oreb, M., Tews, I. & Schleiff, E. Policing Tic 'n' Toc, the doorway to chloroplasts. Trends Cell Biol. 18, 19-27 (2008).
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 19-27
-
-
Oreb, M.1
Tews, I.2
Schleiff, E.3
-
27
-
-
0029041304
-
A chloroplast homologue of the signal recognition particle subunit SRP54 is involved in the posttranslational integration of a protein into thylakoid membranes
-
Li, X., Henry, R., Yuan, J., Cline, K. & Hoffman, N.E. A chloroplast homologue of the signal recognition particle subunit SRP54 is involved in the posttranslational integration of a protein into thylakoid membranes. Proc. Natl. Acad. Sci. USA 92, 3789-3793 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3789-3793
-
-
Li, X.1
Henry, R.2
Yuan, J.3
Cline, K.4
Hoffman, N.E.5
-
28
-
-
0033012091
-
A guide to the Lhc genes and their relatives in Arabidopsis
-
Jansson, S. A guide to the Lhc genes and their relatives in Arabidopsis. Trends Plant Sci. 4, 236-240 (1999).
-
(1999)
Trends Plant Sci.
, vol.4
, pp. 236-240
-
-
Jansson, S.1
-
29
-
-
67649550852
-
Polypeptide translocation by the AAA+ ClpXP protease machine
-
Barkow, S.R., Levchenko, I., Baker, T.A. & Sauer, R.T. Polypeptide translocation by the AAA+ ClpXP protease machine. Chem. Biol. 16, 605-612 (2009).
-
(2009)
Chem. Biol.
, vol.16
, pp. 605-612
-
-
Barkow, S.R.1
Levchenko, I.2
Baker, T.A.3
Sauer, R.T.4
-
30
-
-
0035029482
-
Genetic dissection of the roles of chaperones and proteases in protein folding and degradation in the Escherichia coli cytosol
-
Tomoyasu, T., Mogk, A., Langen, H., Goloubinoff, P. & Bukau, B. Genetic dissection of the roles of chaperones and proteases in protein folding and degradation in the Escherichia coli cytosol. Mol. Microbiol. 40, 397-413 (2001).
-
(2001)
Mol. Microbiol.
, vol.40
, pp. 397-413
-
-
Tomoyasu, T.1
Mogk, A.2
Langen, H.3
Goloubinoff, P.4
Bukau, B.5
-
31
-
-
1642363290
-
Broad yet high substrate specificity: The challenge of AAA+ proteins
-
Mogk, A. et al. Broad yet high substrate specificity: the challenge of AAA+ proteins. J. Struct. Biol. 146, 90-98 (2004).
-
(2004)
J. Struct. Biol.
, vol.146
, pp. 90-98
-
-
Mogk, A.1
-
32
-
-
74649084566
-
The ligand-free state of the TPP riboswitch: A partially folded RNA structure
-
Ali, M., Lipfert, J., Seifert, S., Herschlag, D. & Doniach, S. The ligand-free state of the TPP riboswitch: a partially folded RNA structure. J. Mol. Biol. 396, 153-165 (2010).
-
(2010)
J. Mol. Biol.
, vol.396
, pp. 153-165
-
-
Ali, M.1
Lipfert, J.2
Seifert, S.3
Herschlag, D.4
Doniach, S.5
-
33
-
-
29244433507
-
Three-dimensional solution structures of the chromodomains of cpSRP43
-
Sivaraja, V. et al. Three-dimensional solution structures of the chromodomains of cpSRP43. J. Biol. Chem. 280, 41465-41471 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 41465-41471
-
-
Sivaraja, V.1
-
34
-
-
0033598703
-
Sequential mechanism of solubilization and refolding of stable protein aggregates by a bichaperone network
-
Goloubinoff, P., Mogk, A., Ben Zvi, A.P., Tomoyasu, T. & Bukau, B. Sequential mechanism of solubilization and refolding of stable protein aggregates by a bichaperone network. Proc. Natl. Acad. Sci. USA 96, 13732-13737 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13732-13737
-
-
Goloubinoff, P.1
Mogk, A.2
Ben Zvi, A.P.3
Tomoyasu, T.4
Bukau, B.5
-
35
-
-
0042733148
-
Refolding of substrates bound to small Hsps relies on a disaggregation reaction mediated most efficiently by ClpB/DnaK
-
Mogk, A. et al. Refolding of substrates bound to small Hsps relies on a disaggregation reaction mediated most efficiently by ClpB/DnaK. J. Biol. Chem. 278, 31033-31042 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31033-31042
-
-
Mogk, A.1
-
36
-
-
33846941900
-
Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity
-
Doyle, S.M. et al. Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity. Nat. Struct. Mol. Biol. 14, 114-122 (2007).
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 114-122
-
-
Doyle, S.M.1
-
37
-
-
0037418224
-
MecA, an adaptor protein necessary for ClpC chaperone activity
-
Schlothauer, T., Mogk, A., Dougan, D.A., Bukau, B. & Turgay, K. MecA, an adaptor protein necessary for ClpC chaperone activity. Proc. Natl. Acad. Sci. USA 100, 2306-2311 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2306-2311
-
-
Schlothauer, T.1
Mogk, A.2
Dougan, D.A.3
Bukau, B.4
Turgay, K.5
-
38
-
-
0034705529
-
A thermodynamic coupling mechanism for the disaggregation of a model peptide substrate by chaperone SecB
-
Panse, V.G., Vogel, P., Trommer, W.E. & Varadarajan, R. A thermodynamic coupling mechanism for the disaggregation of a model peptide substrate by chaperone SecB. J. Biol. Chem. 275, 18698-18703 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18698-18703
-
-
Panse, V.G.1
Vogel, P.2
Trommer, W.E.3
Varadarajan, R.4
-
39
-
-
0027949375
-
MSF, a novel cytoplasmic chaperone which functions in precursor targeting to mitochondria
-
Hachiya, N. et al. MSF, a novel cytoplasmic chaperone which functions in precursor targeting to mitochondria. EMBO J. 13, 5146-5154 (1994).
-
(1994)
EMBO J.
, vol.13
, pp. 5146-5154
-
-
Hachiya, N.1
-
40
-
-
0027946119
-
Recognition of mitochondria-targeting signals by a cytosolic import stimulation factor,MSF
-
Komiya, T., Hachiya, N., Sakaguchi, M., Omura, T. & Mihara, K. Recognition of mitochondria-targeting signals by a cytosolic import stimulation factor, MSF. J. Biol. Chem. 269, 30893-30897 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30893-30897
-
-
Komiya, T.1
Hachiya, N.2
Sakaguchi, M.3
Omura, T.4
Mihara, K.5
-
41
-
-
34347374732
-
Efficient interaction between two GTPases allows the chloroplast SRP pathway to bypass the requirement for an SRP RNA
-
Jaru-Ampornpan, P., Chandrasekar, S. & Shan, S. Efficient interaction between two GTPases allows the chloroplast SRP pathway to bypass the requirement for an SRP RNA. Mol. Biol. Cell 18, 2636-2645 (2007).
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 2636-2645
-
-
Jaru-Ampornpan, P.1
Chandrasekar, S.2
Shan, S.3
-
42
-
-
0037200125
-
ATP stimulates signal recognition particle (SRP)/FtsY-supported protein integration in chloroplasts
-
Yuan, J. et al. ATP stimulates signal recognition particle (SRP)/FtsY-supported protein integration in chloroplasts. J. Biol. Chem. 277, 32400-32404 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32400-32404
-
-
Yuan, J.1
-
43
-
-
0026243243
-
Mathematical methods in small-angle scattering data analysis
-
Svergun, D.I. Mathematical methods in small-angle scattering data analysis. J. Appl. Crystallogr. 24, 485-492 (1991).
-
(1991)
J. Appl. Crystallogr.
, vol.24
, pp. 485-492
-
-
Svergun, D.I.1
-
44
-
-
0026910457
-
Determination of the regularization parameter in indirect-transform methods using perceptual criteria
-
Svergun, D.I. Determination of the regularization parameter in indirect-transform methods using perceptual criteria. J. Appl. Crystallogr. 25, 495-503 (1992).
-
(1992)
J. Appl. Crystallogr.
, vol.25
, pp. 495-503
-
-
Svergun, D.I.1
-
45
-
-
0033001996
-
Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing
-
Svergun, D.I. Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing. Biophys. J. 76, 2879-2886 (1999).
-
(1999)
Biophys. J.
, vol.76
, pp. 2879-2886
-
-
Svergun, D.I.1
-
46
-
-
0035010533
-
Determination of domain structure of proteins from X-ray solution scattering
-
Svergun, D.I., Petoukhov, M.V. & Koch, M.H.J. Determination of domain structure of proteins from X-ray solution scattering. Biophys. J. 80, 2946-2953 (2001).
-
(2001)
Biophys. J.
, vol.80
, pp. 2946-2953
-
-
Svergun, D.I.1
Petoukhov, M.V.2
Koch, M.H.J.3
-
47
-
-
0035124442
-
Automated matching of high and low resolution structural models
-
Kozin, M. & Svergun, D.I. Automated matching of high and low resolution structural models. J. Appl. Crystallogr. 34, 33-41 (2001).
-
(2001)
J. Appl. Crystallogr.
, vol.34
, pp. 33-41
-
-
Kozin, M.1
Svergun, D.I.2
-
48
-
-
0037701585
-
Uniqueness of ab initio shape determination in small-angle scattering
-
Volkov, V. & Svergun, D.I. Uniqueness of ab initio shape determination in small-angle scattering. J. Appl. Crystallogr. 36, 860-864 (2003).
-
(2003)
J. Appl. Crystallogr.
, vol.36
, pp. 860-864
-
-
Volkov, V.1
Svergun, D.I.2
-
49
-
-
0032780181
-
Situs: A package for docking crystal structures into low-resolution maps from electron microscopy
-
Wriggers, W., Milligan, R.A. & McCammon, J.A. Situs: a package for docking crystal structures into low-resolution maps from electron microscopy. J. Struct. Biol. 125, 185-195 (1999).
-
(1999)
J. Struct. Biol.
, vol.125
, pp. 185-195
-
-
Wriggers, W.1
Milligan, R.A.2
McCammon, J.A.3
-
50
-
-
0035209087
-
Using Situs for the registration of protein structures with low-resolution bead models from X-ray solution scattering
-
Wriggers, W. & Chacon, P. Using Situs for the registration of protein structures with low-resolution bead models from X-ray solution scattering. J. Appl. Crystallogr. 34, 773-776 (2001).
-
(2001)
J. Appl. Crystallogr.
, vol.34
, pp. 773-776
-
-
Wriggers, W.1
Chacon, P.2
-
51
-
-
4444221565
-
UCSF Chimera\a visualization system for exploratory research and analysis
-
Pettersen, E. et al. UCSF Chimera\a visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605-1612 (2004).
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.1
|