메뉴 건너뛰기




Volumn 16, Issue 19, 2010, Pages 2448-2450

Herbal extracts as hepatoprotectants against acetaminophen hepatotoxicity

Author keywords

Acetaminophen; Drug hepatotoxicity; Herbal extracts; N acetylcysteine

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; DNA FRAGMENT; ENDONUCLEASE G; GENTIANA MANSCHURICA EXTRACT; GLUTATHIONE; HERBACEOUS AGENT; PARACETAMOL; UNCLASSIFIED DRUG;

EID: 77953221729     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v16.i19.2448     Document Type: Article
Times cited : (28)

References (17)
  • 1
    • 75349087892 scopus 로고    scopus 로고
    • Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway
    • Wang AY, Lian LH, Jiang YZ, Wu YL, Nan JX. Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway. World J Gastroenterol 2010; 16: 384-391
    • (2010) World J Gastroenterol , vol.16 , pp. 384-391
    • Wang, A.Y.1    Lian, L.H.2    Jiang, Y.Z.3    Wu, Y.L.4    Nan, J.X.5
  • 2
    • 0036304261 scopus 로고    scopus 로고
    • Mode of cell death after acetaminophen overdose in mice: Apoptosis or oncotic necrosis?
    • Gujral JS, Knight TR, Farhood A, Bajt ML, Jaeschke H. Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis? Toxicol Sci 2002; 67: 322-328
    • (2002) Toxicol Sci , vol.67 , pp. 322-328
    • Gujral, J.S.1    Knight, T.R.2    Farhood, A.3    Bajt, M.L.4    Jaeschke, H.5
  • 3
    • 0141594593 scopus 로고    scopus 로고
    • Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury
    • Jaeschke H, Lemasters JJ. Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury. Gastroenterology 2003; 125: 1246-1257
    • (2003) Gastroenterology , vol.125 , pp. 1246-1257
    • Jaeschke, H.1    Lemasters, J.J.2
  • 5
    • 33749617086 scopus 로고    scopus 로고
    • Nuclear translo-cation of endonuclease G and apoptosis-inducing factor during acetaminophen-induced liver cell injury
    • Bajt ML, Cover C, Lemasters JJ, Jaeschke H. Nuclear translo-cation of endonuclease G and apoptosis-inducing factor during acetaminophen-induced liver cell injury. Toxicol Sci 2006; 94: 217-225
    • (2006) Toxicol Sci , vol.94 , pp. 217-225
    • Bajt, M.L.1    Cover, C.2    Lemasters, J.J.3    Jaeschke, H.4
  • 7
    • 2342529871 scopus 로고    scopus 로고
    • Apoptosis and necrosis in liver disease
    • Jaeschke H, Gujral JS, Bajt ML. Apoptosis and necrosis in liver disease. Liver Int 2004; 24: 85-89
    • (2004) Liver Int , vol.24 , pp. 85-89
    • Jaeschke, H.1    Gujral, J.S.2    Bajt, M.L.3
  • 8
    • 0033135845 scopus 로고    scopus 로고
    • Inhibition of Fas receptor (CD95)-induced hepatic caspase activation and apoptosis by acetaminophen in mice
    • Lawson JA, Fisher MA, Simmons CA, Farhood A, Jaeschke H. Inhibition of Fas receptor (CD95)-induced hepatic caspase activation and apoptosis by acetaminophen in mice. Toxicol Appl Pharmacol 1999; 156: 179-186
    • (1999) Toxicol Appl Pharmacol , vol.156 , pp. 179-186
    • Lawson, J.A.1    Fisher, M.A.2    Simmons, C.A.3    Farhood, A.4    Jaeschke, H.5
  • 9
    • 33244469737 scopus 로고    scopus 로고
    • Role of caspases in acetamin-ophen-induced liver injury
    • Jaeschke H, Cover C, Bajt ML. Role of caspases in acetamin-ophen-induced liver injury. Life Sci 2006; 78: 1670-1676
    • (2006) Life Sci , vol.78 , pp. 1670-1676
    • Jaeschke, H.1    Cover, C.2    Bajt, M.L.3
  • 10
    • 4344576889 scopus 로고    scopus 로고
    • Acetamin-ophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: Protection by N-acetyl cysteine
    • Bajt ML, Knight TR, Lemasters JJ, Jaeschke H. Acetamin-ophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: protection by N-acetyl cysteine. Toxicol Sci 2004; 80: 343-349
    • (2004) Toxicol Sci , vol.80 , pp. 343-349
    • Bajt, M.L.1    Knight, T.R.2    Lemasters, J.J.3    Jaeschke, H.4
  • 11
    • 77953198487 scopus 로고    scopus 로고
    • Acetaminophen-induced injury in HepaRG cells: A novel human cell line for studies of drug hepatotoxicity (abstract)
    • McGill MR, Yan HM, Jaeschke H. Acetaminophen-induced injury in HepaRG cells: a novel human cell line for studies of drug hepatotoxicity (abstract). FASEB J 2010; 24: 759
    • (2010) FASEB J , vol.24 , pp. 759
    • McGill, M.R.1    Yan, H.M.2    Jaeschke, H.3
  • 12
    • 0043135016 scopus 로고    scopus 로고
    • The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxic-ity
    • Jaeschke H, Knight TR, Bajt ML. The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxic-ity. Toxicol Lett 2003; 144: 279-288
    • (2003) Toxicol Lett , vol.144 , pp. 279-288
    • Jaeschke, H.1    Knight, T.R.2    Bajt, M.L.3
  • 13
    • 0036828064 scopus 로고    scopus 로고
    • Peroxynitrite is a critical mediator of acetaminophen hepatotoxicity in murine livers: Protection by glutathione
    • Knight TR, Ho YS, Farhood A, Jaeschke H. Peroxynitrite is a critical mediator of acetaminophen hepatotoxicity in murine livers: protection by glutathione. J Pharmacol Exp Ther 2002; 303: 468-475
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 468-475
    • Knight, T.R.1    Ho, Y.S.2    Farhood, A.3    Jaeschke, H.4
  • 15
    • 0020431315 scopus 로고
    • Drug-induced lipid peroxidation in mice--III. Glutathione content of liver, kidney and spleen after intravenous administration of free and liposomally entrapped glutathione
    • Wendel A, Jaeschke H. Drug-induced lipid peroxidation in mice--III. Glutathione content of liver, kidney and spleen after intravenous administration of free and liposomally entrapped glutathione. Biochem Pharmacol 1982; 31: 3607-3611
    • (1982) Biochem Pharmacol , vol.31 , pp. 3607-3611
    • Wendel, A.1    Jaeschke, H.2
  • 16
    • 0021955464 scopus 로고
    • Effects of N-acetylcysteine on acetaminophen covalent binding and hepatic necrosis in mice
    • Corcoran GB, Racz WJ, Smith CV, Mitchell JR. Effects of N-acetylcysteine on acetaminophen covalent binding and hepatic necrosis in mice. J Pharmacol Exp Ther 1985; 232:864-872
    • (1985) J Pharmacol Exp Ther , vol.232 , pp. 864-872
    • Corcoran, G.B.1    Racz, W.J.2    Smith, C.V.3    Mitchell, J.R.4
  • 17
    • 73449143152 scopus 로고    scopus 로고
    • Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine
    • Saito C, Zwingmann C, Jaeschke H. Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine. Hepatology 2010; 51: 246-254
    • (2010) Hepatology , vol.51 , pp. 246-254
    • Saito, C.1    Zwingmann, C.2    Jaeschke, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.