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Volumn 13, Issue 1, 2010, Pages 5-13

Cancer vaccines targeting HER2/neu for early breast cancer

Author keywords

Breast neoplasms; Dendritic cells; Her2 neu; Vaccines

Indexed keywords

AROMATASE; CANCER VACCINE; CYCLOOXYGENASE 2; CYTOTOXIC AGENT; DENDRITIC CELL VACCINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2 ANTIBODY; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; PEPTIDE VACCINE; TOLL LIKE RECEPTOR AGONIST; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 77953214770     PISSN: 17386756     EISSN: None     Source Type: Journal    
DOI: 10.4048/jbc.2010.13.1.5     Document Type: Article
Times cited : (2)

References (60)
  • 1
    • 16444378335 scopus 로고    scopus 로고
    • Breast cancer vaccines: Maximizing cancer treatment by tapping into host immunity
    • Emens LA, Reilly RT, Jaffee EM. Breast cancer vaccines: maximizing cancer treatment by tapping into host immunity. Endocr Relat Cancer 2005;12:1-17.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 1-17
    • Emens, L.A.1    Reilly, R.T.2    Jaffee, E.M.3
  • 3
    • 0034600849 scopus 로고    scopus 로고
    • The ErbB signaling network: Receptor heterodimerization in development and cancer
    • Olayioye MA, Neve RM, Lane HA, Hynes NE. The ErbB signaling network: receptor heterodimerization in development and cancer. Embo J 2000;19:3159-67.
    • (2000) Embo J , vol.19 , pp. 3159-3167
    • Olayioye, M.A.1    Neve, R.M.2    Lane, H.A.3    Hynes, N.E.4
  • 4
    • 0035868342 scopus 로고    scopus 로고
    • Her2/neu overxpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN
    • Pianetti S, Arsura M, Romieu-Mourez R, Coffey RJ, Sonenshein GE. Her2/neu overxpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN. Oncogene 2001; 20:1287-99.
    • (2001) Oncogene , vol.20 , pp. 1287-1299
    • Pianetti, S.1    Arsura, M.2    Romieu-Mourez, R.3    Coffey, R.J.4    Sonenshein, G.E.5
  • 5
  • 6
    • 0035122438 scopus 로고    scopus 로고
    • The value of the human epidermal growth factor receptor-2 (HER2) as a prognostic marker
    • Cooke T, Reeves J, Lannigan A, Stanton P. The value of the human epidermal growth factor receptor-2 (HER2) as a prognostic marker. Eur J Cancer 2001;34 (Suppp 1):S3-10.
    • (2001) Eur J Cancer , vol.34 , Issue.1 SUPPL.
    • Cooke, T.1    Reeves, J.2    Lannigan, A.3    Stanton, P.4
  • 7
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the HER2/neu oncogene. Science 1987;235:177-82.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 8
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, Bajamonde A, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344:783-92.
    • (2001) N Engl J Med , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3    Fuchs, H.4    Paton, V.5    Bajamonde, A.6
  • 11
    • 0030657467 scopus 로고    scopus 로고
    • High-titer HER2/neu protein-specific antibody can be detected in patients with early-stage breast cancer
    • Disis ML, Pupa SM, Gralow JR, Dittadi R, Menard S, Cheever MA. High-titer HER2/neu protein-specific antibody can be detected in patients with early-stage breast cancer. J Clin Oncol 1997;15:3363-7.
    • (1997) J Clin Oncol , vol.15 , pp. 3363-3367
    • Disis, M.L.1    Pupa, S.M.2    Gralow, J.R.3    Dittadi, R.4    Menard, S.5    Cheever, M.A.6
  • 12
    • 0033754789 scopus 로고    scopus 로고
    • Preexistent immunity to the HER2/neu oncogenic protein in patients with HER2/neu overexpressing breast and ovarian cancer
    • Disis ML, Knutson KL, Schiffman K, Rinn K, McNeel DG. Preexistent immunity to the HER2/neu oncogenic protein in patients with HER2/neu overexpressing breast and ovarian cancer. Breast Cancer Res Treat 2000;62:245-52.
    • (2000) Breast Cancer Res Treat , vol.62 , pp. 245-252
    • Disis, M.L.1    Knutson, K.L.2    Schiffman, K.3    Rinn, K.4    McNeel, D.G.5
  • 13
    • 0023943270 scopus 로고
    • Monoclonal antibodies specific for the neu oncogene product directly mediate anti-tumor effects in vivo
    • Drebin JA, Link VC, Greene MI. Monoclonal antibodies specific for the neu oncogene product directly mediate anti-tumor effects in vivo. Oncogene 1988;2:387-94.
    • (1988) Oncogene , vol.2 , pp. 387-394
    • Drebin, J.A.1    Link, V.C.2    Greene, M.I.3
  • 14
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • Cobleigh MA, Vogel CL, Tripathy D, Robert NJ, Scholl S, Fehrenbacher L, et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999;17:2639-48.
    • (1999) J Clin Oncol , vol.17 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3    Robert, N.J.4    Scholl, S.5    Fehrenbacher, L.6
  • 15
    • 0036534121 scopus 로고    scopus 로고
    • Phase II study of weekly docetaxel and trastuzumab for patients with HER2 overexpressing metastatic breast cancer
    • Esteva FJ, Valero V, Booser D, Guerra LT, Murray JL, Pusztai L, et al. Phase II study of weekly docetaxel and trastuzumab for patients with HER2 overexpressing metastatic breast cancer. J Clin Oncol 2002;20:1800-8.
    • (2002) J Clin Oncol , vol.20 , pp. 1800-1808
    • Esteva, F.J.1    Valero, V.2    Booser, D.3    Guerra, L.T.4    Murray, J.L.5    Pusztai, L.6
  • 16
    • 33645538673 scopus 로고    scopus 로고
    • Analysis of trastuzumab and chemotherapy in advanced breast cancer after the failure of at least one earlier combination: An observational study
    • Bartsch R, Wenzel C, Hussian D, Pluschnig U, Sevelda U, Koestler W, et al. Analysis of trastuzumab and chemotherapy in advanced breast cancer after the failure of at least one earlier combination: an observational study. BMC Cancer 2006;6:63.
    • (2006) BMC Cancer , vol.6 , pp. 63
    • Bartsch, R.1    Wenzel, C.2    Hussian, D.3    Pluschnig, U.4    Sevelda, U.5    Koestler, W.6
  • 18
    • 33748642331 scopus 로고    scopus 로고
    • Long-term cardiac tolerability of trastuzumab in metastatic breast cancer: The M.D. Anderson Cancer Center experience
    • Guarneri V, Lenihan DJ, Valero V, Durand JB, Broglio K, Hess KR, et al. Long-term cardiac tolerability of trastuzumab in metastatic breast cancer: the M.D. Anderson Cancer Center experience. J Clin Oncol 2006;24:4107-15.
    • (2006) J Clin Oncol , vol.24 , pp. 4107-4115
    • Guarneri, V.1    Lenihan, D.J.2    Valero, V.3    Durand, J.B.4    Broglio, K.5    Hess, K.R.6
  • 19
    • 0036847689 scopus 로고    scopus 로고
    • Toxicity, immunogenicity, and induction of E75-specific tumor-lytic CTLs by HER2 Peptide E75(369-377) combined with granulocyte macrophage colony-stimulating factor in HLAA2+ patients with metastatic breast and ovarian cancer
    • Murray JL, Gillogly ME, Przepiorka D, Brewer H, Ibrahim NK, Booser DJ, et al. Toxicity, immunogenicity, and induction of E75-specific tumor-lytic CTLs by HER2 Peptide E75(369-377) combined with granulocyte macrophage colony-stimulating factor in HLAA2+ patients with metastatic breast and ovarian cancer. Clin Cancer Res 2002;8:3407-18.
    • (2002) Clin Cancer Res , vol.8 , pp. 3407-3418
    • Murray, J.L.1    Gillogly, M.E.2    Przepiorka, D.3    Brewer, H.4    Ibrahim, N.K.5    Booser, D.J.6
  • 20
    • 0036605567 scopus 로고    scopus 로고
    • Generation of T-cell immunity to the HER2/neu protein after active immunization with HER2/neu peptide-based vaccines
    • Disis ML, Gooley TA, Rinn K, Davis D, Piepkorn M, Cheever MA, et al. Generation of T-cell immunity to the HER2/neu protein after active immunization with HER2/neu peptide-based vaccines. J Clin Oncol 2002;20:2624-32.
    • (2002) J Clin Oncol , vol.20 , pp. 2624-2632
    • Disis, M.L.1    Gooley, T.A.2    Rinn, K.3    Davis, D.4    Piepkorn, M.5    Cheever, M.A.6
  • 21
    • 27144464759 scopus 로고    scopus 로고
    • Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients
    • Peoples GE, Gurney JM, Hueman MT, Woll MM, Ryan GB, Storrer CE, et al. Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients. J Clin Oncol 2005;23: 7536-45.
    • (2005) J Clin Oncol , vol.23 , pp. 7536-7545
    • Peoples, G.E.1    Gurney, J.M.2    Hueman, M.T.3    Woll, M.M.4    Ryan, G.B.5    Storrer, C.E.6
  • 23
    • 4544252430 scopus 로고    scopus 로고
    • Humoral epitopespreading following immunization with a HER2/neu peptide based vaccine in cancer patients
    • Disis ML, Goodell V, Schiffman K, Knutson KL. Humoral epitopespreading following immunization with a HER2/neu peptide based vaccine in cancer patients. J Clin Immunol 2004;24:571-8.
    • (2004) J Clin Immunol , vol.24 , pp. 571-578
    • Disis, M.L.1    Goodell, V.2    Schiffman, K.3    Knutson, K.L.4
  • 25
    • 0032991359 scopus 로고    scopus 로고
    • Vaccination with the extracellular domain of p185neu prevents mammary tumor development in neu transgenic mice
    • Esserman LJ, Lopez T, Montes R, Bald LN, Fendly BM, Campbell MJ. Vaccination with the extracellular domain of p185neu prevents mammary tumor development in neu transgenic mice. Cancer Immunol Immunother 1999;47:337-42.
    • (1999) Cancer Immunol Immunother , vol.47 , pp. 337-342
    • Esserman, L.J.1    Lopez, T.2    Montes, R.3    Bald, L.N.4    Fendly, B.M.5    Campbell, M.J.6
  • 26
    • 15444370728 scopus 로고    scopus 로고
    • Early role of CD4+ Th1 cells and antibodies in HER2 adenovirus vaccine protection against autochthonous mammary carcinomas
    • Park JM, Terabe M, Sakai Y, Munasinghe J, Forni G, Morris JC, et al. Early role of CD4+ Th1 cells and antibodies in HER2 adenovirus vaccine protection against autochthonous mammary carcinomas. J Immunol 2005;174:4228-36.
    • (2005) J Immunol , vol.174 , pp. 4228-4236
    • Park, J.M.1    Terabe, M.2    Sakai, Y.3    Munasinghe, J.4    Forni, G.5    Morris, J.C.6
  • 27
    • 4043174820 scopus 로고    scopus 로고
    • Immunoprevention of mammary carcinoma in HER2/neu transgenic mice is IFN-gamma and B cell dependent
    • Nanni P, Landuzzi L, Nicoletti G, De Giovanni C, Rossi I, Croci S, et al. Immunoprevention of mammary carcinoma in HER2/neu transgenic mice is IFN-gamma and B cell dependent. J Immunol 2004; 173:2288-96.
    • (2004) J Immunol , vol.173 , pp. 2288-2296
    • Nanni, P.1    Landuzzi, L.2    Nicoletti, G.3    de Giovanni, C.4    Rossi, I.5    Croci, S.6
  • 28
    • 33847764924 scopus 로고    scopus 로고
    • Targeting HER2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion
    • Czerniecki BJ, Koski GK, Koldovsky U, Xu S, Cohen PA, Mick R, et al. Targeting HER2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion. Cancer Res 2007;67:1842-52.
    • (2007) Cancer Res , vol.67 , pp. 1842-1852
    • Czerniecki, B.J.1    Koski, G.K.2    Koldovsky, U.3    Xu, S.4    Cohen, P.A.5    Mick, R.6
  • 29
    • 33645023639 scopus 로고    scopus 로고
    • Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: The role of T regulatory cells
    • Taylor A, Verhagen J, Blaser K, Akdis M, Akdis CA. Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells. Immunology 2006;117: 433-42.
    • (2006) Immunology , vol.117 , pp. 433-442
    • Taylor, A.1    Verhagen, J.2    Blaser, K.3    Akdis, M.4    Akdis, C.A.5
  • 31
    • 20044363610 scopus 로고    scopus 로고
    • CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells
    • Antony PA, Piccirillo CA, Akpinarli A, Finkelstein SE, Speiss PJ, Surman DR, et al. CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells. J Immunol 2005;174:2591-601.
    • (2005) J Immunol , vol.174 , pp. 2591-2601
    • Antony, P.A.1    Piccirillo, C.A.2    Akpinarli, A.3    Finkelstein, S.E.4    Speiss, P.J.5    Surman, D.R.6
  • 32
    • 33745914659 scopus 로고    scopus 로고
    • Levels of circulating regulatory CD4+CD25+ T cells are decreased in breast cancer patients after vaccination with a HER2/neu peptide (E75) and GM-CSF vaccine
    • Hueman MT, Stojadinovic A, Storrer CE, Foley RJ, Gurney JM, Shriver CD, et al. Levels of circulating regulatory CD4+CD25+ T cells are decreased in breast cancer patients after vaccination with a HER2/neu peptide (E75) and GM-CSF vaccine. Breast Cancer Res Treat 2006;98:17-29.
    • (2006) Breast Cancer Res Treat , vol.98 , pp. 17-29
    • Hueman, M.T.1    Stojadinovic, A.2    Storrer, C.E.3    Foley, R.J.4    Gurney, J.M.5    Shriver, C.D.6
  • 34
    • 1642497640 scopus 로고    scopus 로고
    • Tumorspecific human CD4+ regulatory T cells and their ligands: Implications for immunotherapy
    • Wang HY, Lee DA, Peng G, Guo Z, Li Y, Kiniwa Y, et al. Tumorspecific human CD4+ regulatory T cells and their ligands: implications for immunotherapy. Immunity 2004;20:107-18.
    • (2004) Immunity , vol.20 , pp. 107-118
    • Wang, H.Y.1    Lee, D.A.2    Peng, G.3    Guo, Z.4    Li, Y.5    Kiniwa, Y.6
  • 35
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 2004;21:137-48.
    • (2004) Immunity , vol.21 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 36
    • 21844459726 scopus 로고    scopus 로고
    • Cancer vaccines 2004 opening address: The molecular and cellular basis of cancer immunosurveillance and immunoediting
    • Schreiber RD. Cancer vaccines 2004 opening address: the molecular and cellular basis of cancer immunosurveillance and immunoediting. Cancer Immun 2005;5 (Suppl 1):1.
    • (2005) Cancer Immun , vol.5 , Issue.1 SUPPL. , pp. 1
    • Schreiber, R.D.1
  • 38
    • 0037066502 scopus 로고    scopus 로고
    • Decoding the patterns of self and nonself by the innate immune system
    • Medzhitov R, Janeway CA Jr. Decoding the patterns of self and nonself by the innate immune system. Science 2002;296:298-300.
    • (2002) Science , vol.296 , pp. 298-300
    • Medzhitov, R.1    Janeway Jr., C.A.2
  • 39
    • 0033067894 scopus 로고    scopus 로고
    • The Toll-receptor family and control of innate immunity
    • Kopp EB, Medzhitov R. The Toll-receptor family and control of innate immunity. Curr Opin Immunol 1999;11:13-8.
    • (1999) Curr Opin Immunol , vol.11 , pp. 13-18
    • Kopp, E.B.1    Medzhitov, R.2
  • 40
    • 0034307339 scopus 로고    scopus 로고
    • The Toll receptor family and microbial recognition
    • Medzhitov R, Janeway CA Jr. The Toll receptor family and microbial recognition. Trends Microbiol 2000;8:452-6.
    • (2000) Trends Microbiol , vol.8 , pp. 452-456
    • Medzhitov, R.1    Janeway Jr., C.A.2
  • 41
  • 42
    • 24944549093 scopus 로고    scopus 로고
    • The regulation of the expression of inducible nitric oxide synthase by Src-family tyrosine kinases mediated through MyD88 independent signaling pathways of Toll-like receptor 4
    • Lee JY, Lowell CA, Lemay DG, Youn HS, Rhee SH, Sohn KH, et al. The regulation of the expression of inducible nitric oxide synthase by Src-family tyrosine kinases mediated through MyD88 independent signaling pathways of Toll-like receptor 4. Biochem Pharmacol 2005; 70:1231-40.
    • (2005) Biochem Pharmacol , vol.70 , pp. 1231-1240
    • Lee, J.Y.1    Lowell, C.A.2    Lemay, D.G.3    Youn, H.S.4    Rhee, S.H.5    Sohn, K.H.6
  • 43
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signaling
    • Akira S, Takeda K. Toll-like receptor signaling. Nat Rev Immunol 2004;4:499-511.
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 44
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+ CD25+ T cell-mediated suppression by dendritic cells
    • Pasare C, Medzhitov R. Toll pathway-dependent blockade of CD4+ CD25+ T cell-mediated suppression by dendritic cells. Science 2003; 299:1033-6.
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 45
    • 33746841821 scopus 로고    scopus 로고
    • High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid-derived dendritic cells is mediated by IL-12 production
    • Xu S, Koldovsky U, Xu M, Wang D, Fitzpatrick E, Son G, et al. High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid-derived dendritic cells is mediated by IL-12 production. Surgery 2006;140:170-8.
    • (2006) Surgery , vol.140 , pp. 170-178
    • Xu, S.1    Koldovsky, U.2    Xu, M.3    Wang, D.4    Fitzpatrick, E.5    Son, G.6
  • 46
    • 23944489407 scopus 로고    scopus 로고
    • Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
    • Napolitani G, Rinaldi A, Bertoni F, Sallusto F, Lanzavecchia A. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat Immunol 2005;6:769-76.
    • (2005) Nat Immunol , vol.6 , pp. 769-776
    • Napolitani, G.1    Rinaldi, A.2    Bertoni, F.3    Sallusto, F.4    Lanzavecchia, A.5
  • 47
    • 0033486007 scopus 로고    scopus 로고
    • T-cell priming by type-1 and type-2 polarized dendritic cells: The concept of a third signal
    • Kalinski P, Hilkens CM, Wierenga EA, Kapsenberg ML. T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal. Immunol Today 1999;20:561-7.
    • (1999) Immunol Today , vol.20 , pp. 561-567
    • Kalinski, P.1    Hilkens, C.M.2    Wierenga, E.A.3    Kapsenberg, M.L.4
  • 48
    • 0034689206 scopus 로고    scopus 로고
    • Tumor-induced immunosuppression: A barrier to immunotherapy of large tumors by cytokine-secreting tumor vaccine
    • Hsieh CL, Chen DS, Hwang LH. Tumor-induced immunosuppression: a barrier to immunotherapy of large tumors by cytokine-secreting tumor vaccine. Hum Gene Ther 2000;11:681-92.
    • (2000) Hum Gene Ther , vol.11 , pp. 681-692
    • Hsieh, C.L.1    Chen, D.S.2    Hwang, L.H.3
  • 49
    • 33846013255 scopus 로고    scopus 로고
    • Polarized type-1 dendritic cells (DC1) producing high levels of IL-12 family members rescue patient TH1-type antimelanoma CD4+ T cell responses in vitro
    • Wesa A, Kalinski P, Kirkwood JM, Tatsumi T, Storkus WJ. Polarized type-1 dendritic cells (DC1) producing high levels of IL-12 family members rescue patient TH1-type antimelanoma CD4+ T cell responses in vitro. J Immunother 2007;30:75-82.
    • (2007) J Immunother , vol.30 , pp. 75-82
    • Wesa, A.1    Kalinski, P.2    Kirkwood, J.M.3    Tatsumi, T.4    Storkus, W.J.5
  • 50
    • 34547136715 scopus 로고    scopus 로고
    • Development of vaccines for high-risk ductal carcinoma in situ of the breast
    • Czerniecki BJ, Roses RE, Koski GK. Development of vaccines for high-risk ductal carcinoma in situ of the breast. Cancer Res 2007;67: 6531-4.
    • (2007) Cancer Res , vol.67 , pp. 6531-6534
    • Czerniecki, B.J.1    Roses, R.E.2    Koski, G.K.3
  • 51
    • 22244446128 scopus 로고    scopus 로고
    • Serum HER-2/neu conversion to positive at the time of disease progression in patients with breast carcinoma on hormone therapy
    • Lipton A, Leitzel K, Ali SM, Demers L, Harvey HA, Chaudri-Ross HA, et al. Serum HER-2/neu conversion to positive at the time of disease progression in patients with breast carcinoma on hormone therapy. Cancer 2005;104:257-63.
    • (2005) Cancer , vol.104 , pp. 257-263
    • Lipton, A.1    Leitzel, K.2    Ali, S.M.3    Demers, L.4    Harvey, H.A.5    Chaudri-Ross, H.A.6
  • 52
    • 0026496741 scopus 로고
    • Transcriptional repression of the neu protooncogene by estrogen stimulated estrogen receptor
    • Russell KS, Hung MC. Transcriptional repression of the neu protooncogene by estrogen stimulated estrogen receptor. Cancer Res 1992;52:6624-9.
    • (1992) Cancer Res , vol.52 , pp. 6624-6629
    • Russell, K.S.1    Hung, M.C.2
  • 54
    • 0141455509 scopus 로고    scopus 로고
    • Interactions between estrogen and growth factor receptors in human breast cancers and the tumor-associated vasculature
    • Pietras RJ. Interactions between estrogen and growth factor receptors in human breast cancers and the tumor-associated vasculature. Breast J 2003;9:361-73.
    • (2003) Breast J , vol.9 , pp. 361-373
    • Pietras, R.J.1
  • 55
    • 12144269500 scopus 로고    scopus 로고
    • Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer
    • Osborne CK, Shou J, Massarweh S, Schiff R. Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer. Clin Cancer Res 2005; 11:865S-70S.
    • (2005) Clin Cancer Res , vol.11
    • Osborne, C.K.1    Shou, J.2    Massarweh, S.3    Schiff, R.4
  • 56
    • 33744933461 scopus 로고    scopus 로고
    • HER-2/neu status is a determinant of mammary aromatase activity in vivo: Evidence for a cyclooxygenase-2-dependent mechanism
    • Subbaramaiah K, Howe LR, Port ER, Brogi E, Fishman J, Liu CH, et al. HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism. Cancer Res 2006;66:5504-11.
    • (2006) Cancer Res , vol.66 , pp. 5504-5511
    • Subbaramaiah, K.1    Howe, L.R.2    Port, E.R.3    Brogi, E.4    Fishman, J.5    Liu, C.H.6
  • 57
    • 24644453938 scopus 로고    scopus 로고
    • In vitro and in vivo effects of combination of trastuzumab (Herceptin) and tamoxifen in breast cancer
    • Wang CX, Koay DC, Edwards A, Lu Z, Mor G, Ocal IT, et al. In vitro and in vivo effects of combination of trastuzumab (Herceptin) and tamoxifen in breast cancer. Breast Cancer Res Treat 2005;92:251-63.
    • (2005) Breast Cancer Res Treat , vol.92 , pp. 251-263
    • Wang, C.X.1    Koay, D.C.2    Edwards, A.3    Lu, Z.4    Mor, G.5    Ocal, I.T.6
  • 58
    • 33847147996 scopus 로고    scopus 로고
    • The combination of letrozole and trastuzumab as first or second-line biological therapy produces durable responses in a subset of HER2 positive and ER positive advanced breast cancers
    • Marcom PK, Isaacs C, Harris L, Wong ZW, Kommarreddy A, Novielli N, et al. The combination of letrozole and trastuzumab as first or second-line biological therapy produces durable responses in a subset of HER2 positive and ER positive advanced breast cancers. Breast Cancer Res Treat 2007;102:43-9.
    • (2007) Breast Cancer Res Treat , vol.102 , pp. 43-49
    • Marcom, P.K.1    Isaacs, C.2    Harris, L.3    Wong, Z.W.4    Kommarreddy, A.5    Novielli, N.6
  • 59
    • 33748347895 scopus 로고    scopus 로고
    • Investigating the combination of trastuzumab and HER2/neu peptide vaccines for the treatment of breast cancer
    • Mittendorf EA, Storrer CE, Shriver CD, Ponniah S, Peoples GE. Investigating the combination of trastuzumab and HER2/neu peptide vaccines for the treatment of breast cancer. Ann Surg Oncol 2006;13:1085-98.
    • (2006) Ann Surg Oncol , vol.13 , pp. 1085-1098
    • Mittendorf, E.A.1    Storrer, C.E.2    Shriver, C.D.3    Ponniah, S.4    Peoples, G.E.5
  • 60
    • 10044236900 scopus 로고    scopus 로고
    • Augmenting the potency of breast cancer vaccines: Combined modality immunotherapy
    • Emens LA, Reilly RT, Jaffee EM. Augmenting the potency of breast cancer vaccines: combined modality immunotherapy. Breast Dis 2004;20:13-24.
    • (2004) Breast Dis , vol.20 , pp. 13-24
    • Emens, L.A.1    Reilly, R.T.2    Jaffee, E.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.