메뉴 건너뛰기




Volumn 151, Issue 5, 2010, Pages 2008-2018

The positive effects of growth hormone-releasing peptide-6 on weight gain and fat mass accrual depend on the insulin/glucose status

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; AGOUTI RELATED PROTEIN; C PEPTIDE; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; FATTY ACID SYNTHASE; GHRELIN; GLUCOSE; GLUCOSE TRANSPORTER 4; GROWTH HORMONE; HISTIDYL DEXTRO TRYPTOPHYLALANYLTRYPTOPHYL DEXTRO PHENYLALANYLLYSINAMIDE; INSULIN; LEPTIN; MESSENGER RNA; NEUROPEPTIDE Y; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROOPIOMELANOCORTIN; SOMATOMEDIN C; FAT; GROWTH HORMONE RELEASING HEXAPEPTIDE; INSULIN LIKE GROWTH FACTOR 1, RAT; INSULIN-LIKE GROWTH FACTOR-1, RAT; OLIGOPEPTIDE;

EID: 77953168184     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-1394     Document Type: Article
Times cited : (10)

References (61)
  • 3
    • 0029806442 scopus 로고    scopus 로고
    • Intracerebroventricular administration of the growth hormone-releasing peptide KP-102 increases food intake in free feeding rats
    • Okada K, Ishii S, Minami S, Sugihara H, Shibasaki T, Wakabayashi I 1996 Intracerebroventricular administration of the growth hormone-releasing peptide KP-102 increases food intake in free feeding rats. Endocrinology 137:5155-5158
    • (1996) Endocrinology , vol.137 , pp. 5155-5158
    • Okada, K.1    Ishii, S.2    Minami, S.3    Sugihara, H.4    Shibasaki, T.5    Wakabayashi, I.6
  • 7
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschöp M, Smiley DL, Heiman ML 2000 Ghrelin induces adiposity in rodents. Nature 407:908-913
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschöp, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 14
    • 0035513696 scopus 로고    scopus 로고
    • Chronic Central Infusion of Ghrelin Increases Hypothalamic Neuropeptide Y and Agouti-Related Protein mRNA Levels and Body Weight in Rats
    • Kamegai J, Tamura H, Shimizu T, Ishii S, Sugihara H, Wakabayashi I 2001 Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and agouti-related protein mRNA levels and body weight in rats. Diabetes 50:2438-2443 (Pubitemid 33642759)
    • (2001) Diabetes , vol.50 , Issue.7-12 , pp. 2438-2443
    • Kamegai, J.1    Tamura, H.2    Shimizu, T.3    Ishii, S.4    Sugihara, H.5    Wakabayashi, I.6
  • 19
    • 0025612094 scopus 로고
    • Localization of insulin receptor mRNA in rat brain by in situ hybridization
    • Marks JL, Porte Jr D, Stahl WL, Baskin DG 1990 Localization of insulin receptor mRNA in rat brain by in situ hybridization. Endocrinology 127:3234-3236
    • (1990) Endocrinology , vol.127 , pp. 3234-3236
    • Marks, J.L.1    Porte Jr., D.2    Stahl, W.L.3    Baskin, D.G.4
  • 20
    • 0021136310 scopus 로고
    • Primary culture of isolated adipocytes. A new model to study insulin receptor regulation and insulin action
    • Marshall S, Garvey WT, Geller M 1984 Primary culture of isolated adipocytes. A new model to study insulin receptor regulation and insulin action. J Biol Chem 259:6376-6384
    • (1984) J Biol Chem , vol.259 , pp. 6376-6384
    • Marshall, S.1    Garvey, W.T.2    Geller, M.3
  • 21
    • 0036894327 scopus 로고    scopus 로고
    • The rat arcuate nucleus integrates peripheral signals provided by leptin, insulin, and a ghrelin mimetic
    • Hewson AK, Tung LY, Connell DW, Tookman L, Dickson SL 2002 The rat arcuate nucleus integrates peripheral signals provided by leptin, insulin, and a ghrelin mimetic. Diabetes 51:3412-3419
    • (2002) Diabetes , vol.51 , pp. 3412-3419
    • Hewson, A.K.1    Tung, L.Y.2    Connell, D.W.3    Tookman, L.4    Dickson, S.L.5
  • 24
    • 0027169767 scopus 로고
    • A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples
    • Chomczynski P 1993 A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques 15:532-534:536-537
    • (1993) Biotechniques , vol.15 , Issue.532-534 , pp. 536-537
    • Chomczynski, P.1
  • 25
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2[-ΔΔC(T)] method
    • Livak KJ, Schmittgen TD 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2[-ΔΔC(T)] method. Methods 25:402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 27
    • 54049121817 scopus 로고    scopus 로고
    • The role of ghrelin and ghrelin analogues in wasting disease
    • Kamiji MM, Inui A 2008 The role of ghrelin and ghrelin analogues in wasting disease. Curr Opin Clin Nutr Metab Care 11:443-451
    • (2008) Curr Opin Clin Nutr Metab Care , vol.11 , pp. 443-451
    • Kamiji, M.M.1    Inui, A.2
  • 28
    • 0036150931 scopus 로고    scopus 로고
    • GH-releasing peptide-2 increases fat mass in mice lacking NPY: Indication for a crucial mediating role of hypothalamic agouti-related protein
    • Tschöp M, Statnick MA, Suter TM, Heiman ML 2002 GH-releasing peptide-2 increases fat mass in mice lacking NPY: indication for a crucial mediating role of hypothalamic agouti-related protein. Endocrinology 143:558-568
    • (2002) Endocrinology , vol.143 , pp. 558-568
    • Tschöp, M.1    Statnick, M.A.2    Suter, T.M.3    Heiman, M.L.4
  • 31
    • 0041826787 scopus 로고    scopus 로고
    • Growth hormone (GH) hypersecretion and GH receptor resistance in streptozoptocin diabetic mice in response to a GH secretagogue
    • Johansen PB, Segev Y, Landau D, Phillip M, Flyvbjerg A 2003 Growth hormone (GH) hypersecretion and GH receptor resistance in streptozotocin diabetic mice in response to a GH secretagogue. Exp Diabesity Res 4:73-81 (Pubitemid 37080775)
    • (2003) Experimental Diabesity Research , vol.4 , Issue.2 , pp. 73-81
    • Johansen, P.B.1    Segev, Y.2    Landau, D.3    Phillip, M.4    Flyvbjerg, A.5
  • 33
    • 33846435771 scopus 로고    scopus 로고
    • Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic β-cells and human islets: Involvement of 3′,5′-cyclic adenosine monophosphate/ protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-kinase/Akt signaling
    • Granata R, Settanni F, Biancone L, Trovato L, Nano R, Bertuzzi F, Destefanis S, Annunziata M, Martinetti M, Catapano F, Ghè C, Isgaard J, Papotti M, Ghigo E, Muccioli G 2007 Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic β-cells and human islets: involvement of 3′,5′-cyclic adenosine monophosphate/ protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-kinase/Akt signaling. Endocrinology 148: 512-529
    • (2007) Endocrinology , vol.148 , pp. 512-529
    • Granata, R.1    Settanni, F.2    Biancone, L.3    Trovato, L.4    Nano, R.5    Bertuzzi, F.6    Destefanis, S.7    Annunziata, M.8    Martinetti, M.9    Catapano, F.10    Ghè, C.11    Isgaard, J.12    Papotti, M.13    Ghigo, E.14    Muccioli, G.15
  • 34
    • 33645868980 scopus 로고    scopus 로고
    • Ontogeny of regeneration of β-cells in the neonatal rat after treatment with streptozotocin
    • Thyssen S, Arany E, Hill DJ 2006 Ontogeny of regeneration of β-cells in the neonatal rat after treatment with streptozotocin. Endocrinology 147:2346-2356
    • (2006) Endocrinology , vol.147 , pp. 2346-2356
    • Thyssen, S.1    Arany, E.2    Hill, D.J.3
  • 35
    • 0033765720 scopus 로고    scopus 로고
    • An ultrastructural study on the effect of streptozotocin on the islets of Langerhans in mice
    • Tokyo
    • Aughsteen AA 2000 An ultrastructural study on the effect of streptozotocin on the islets of Langerhans in mice. J Electron Microsc (Tokyo) 49:681-690
    • (2000) J Electron Microsc , vol.49 , pp. 681-690
    • Aughsteen, A.A.1
  • 36
    • 36348991997 scopus 로고    scopus 로고
    • Insulin-induced immunohistochemical and morphological changes in pancreatic β-cells of streptozotocin-treated diabetic rats
    • Adewole SO, Ojewole JA 2007 Insulin-induced immunohistochemical and morphological changes in pancreatic β-cells of streptozotocin-treated diabetic rats. Methods Find Exp Clin Pharmacol 29: 447-455
    • (2007) Methods Find Exp Clin Pharmacol , vol.29 , pp. 447-455
    • Adewole, S.O.1    Ojewole, J.A.2
  • 37
    • 45749158501 scopus 로고    scopus 로고
    • Control of pancreatic β-cell fate by insulin signaling: The sweet spot hypothesis
    • Johnson JD, Alejandro EU 2008 Control of pancreatic β-cell fate by insulin signaling: the sweet spot hypothesis. Cell Cycle 7:1343-1347
    • (2008) Cell Cycle , vol.7 , pp. 1343-1347
    • Johnson, J.D.1    Alejandro, E.U.2
  • 39
    • 33744982443 scopus 로고    scopus 로고
    • Alteration of the gene and protein levels of insulin-like growth factors in streptozotocin-induced diabetic male rats
    • Han HJ, Park SH 2006 Alteration of the gene and protein levels of insulin-like growth factors in streptozotocin-induced diabetic male rats. J Vet Med Sci 68:413-419
    • (2006) J Vet Med Sci , vol.68 , pp. 413-419
    • Han, H.J.1    Park, S.H.2
  • 42
    • 0021322884 scopus 로고
    • On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone
    • Bowers CY, Momany FA, Reynolds GA, Hong A 1984 On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology 114:1537-1545
    • (1984) Endocrinology , vol.114 , pp. 1537-1545
    • Bowers, C.Y.1    Momany, F.A.2    Reynolds, G.A.3    Hong, A.4
  • 44
    • 0033969423 scopus 로고    scopus 로고
    • Effects of streptozotocin-induced diabetesand insulin treatment on thehypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats
    • Havel PJ, Hahn TM, Sindelar DK, Baskin DG, Dallman MF, Weigle DS, Schwartz MW 2000 Effects of streptozotocin-induced diabetesand insulin treatment on thehypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats. Diabetes 49:244-252
    • (2000) Diabetes , vol.49 , pp. 244-252
    • Havel, P.J.1    Hahn, T.M.2    Sindelar, D.K.3    Baskin, D.G.4    Dallman, M.F.5    Weigle, D.S.6    Schwartz, M.W.7
  • 46
    • 0033436355 scopus 로고    scopus 로고
    • Insulin and leptin: Dual adiposity signals to the brain for the regulation of food intake and body weight
    • DOI 10.1016/S0006-8993(99)01974-5, PII S0006899399019745
    • Baskin DG, Figlewicz Lattemann D, Seeley RJ, Woods SC, Porte Jr D, Schwartz MW 1999 Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight. Brain Res 848:114-123 (Pubitemid 30001660)
    • (1999) Brain Research , vol.848 , Issue.1-2 , pp. 114-123
    • Baskin, D.G.1    Figlewicz Lattemann, D.2    Seeley, R.J.3    Woods, S.C.4    Porte Jr., D.5    Schwartz, M.W.6
  • 47
    • 15244363998 scopus 로고    scopus 로고
    • Effect of centrally administered C75, a fatty acid synthase inhibitor, on ghrelin secretion and its downstream effects
    • Hu Z, Cha SH, van Haasteren G, Wang J, Lane MD 2005 Effect of centrally administered C75, a fatty acid synthase inhibitor, on ghrelin secretion and its downstream effects. Proc Natl Acad Sci USA 102:3972-3977
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3972-3977
    • Hu, Z.1    Cha, S.H.2    Van Haasteren, G.3    Wang, J.4    Lane, M.D.5
  • 48
    • 34248590007 scopus 로고    scopus 로고
    • Sex differences in the regulation of cocaine and amphetamine-regulated transcript expression in hypothalamic nuclei of rats by forced swim stress
    • Gozen O, Balkan B, Yararbas G, Koylu EO, Kuhar MJ, Pogun S 2007 Sex differences in the regulation of cocaine and amphetamine-regulated transcript expression in hypothalamic nuclei of rats by forced swim stress. Synapse 61:561-568
    • (2007) Synapse , vol.61 , pp. 561-568
    • Gozen, O.1    Balkan, B.2    Yararbas, G.3    Koylu, E.O.4    Kuhar, M.J.5    Pogun, S.6
  • 49
    • 0037012795 scopus 로고    scopus 로고
    • Functional characterizations of cocaine- And amphetamine-regulated transcript mRNA expression in rat hypothalamus
    • Li HY, Hwang HW, Hu YH 2002 Functional characterizations of cocaine- and amphetamine-regulated transcript mRNA expression in rat hypothalamus. Neurosci Lett 323:203-206
    • (2002) Neurosci Lett , vol.323 , pp. 203-206
    • Li, H.Y.1    Hwang, H.W.2    Hu, Y.H.3
  • 50
    • 34247324303 scopus 로고    scopus 로고
    • Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein
    • Grünblatt E, Salkovic-Petrisic M, Osmanovic J, Riederer P, Hoyer S 2007 Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein. J Neurochem 101:757-770
    • (2007) J Neurochem , vol.101 , pp. 757-770
    • Grünblatt, E.1    Salkovic-Petrisic, M.2    Osmanovic, J.3    Riederer, P.4    Hoyer, S.5
  • 51
    • 0026786571 scopus 로고
    • Tissue-specific regulation of insulin receptor mRNA levels in rats with STZ-induced diabetes mellitus
    • Sechi LA, Griffin CA, Grady EF, Grunfeld C, Kalinyak JE, Schambelan M1992 Tissue-specific regulation of insulin receptor mRNA levels in rats with STZ-induced diabetes mellitus. Diabetes 41:1113-1118
    • (1992) Diabetes , vol.41 , pp. 1113-1118
    • Sechi, L.A.1    Griffin, C.A.2    Grady, E.F.3    Grunfeld, C.4    Kalinyak, J.E.5    Schambelan, M.6
  • 52
    • 1042275336 scopus 로고    scopus 로고
    • Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor
    • Thompson NM, Gill DA, Davies R, Loveridge N, Houston PA, Robinson IC, Wells T 2004 Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor. Endocrinology 145:234-242
    • (2004) Endocrinology , vol.145 , pp. 234-242
    • Thompson, N.M.1    Gill, D.A.2    Davies, R.3    Loveridge, N.4    Houston, P.A.5    Robinson, I.C.6    Wells, T.7
  • 54
    • 0027312832 scopus 로고
    • Expression of the adipocyte fatty acid-binding protein in streptozotocin-diabetes: Effects of insulin deficiency and supplementation
    • Melki SA, Abumrad NA 1993 Expression of the adipocyte fatty acid-binding protein in streptozotocin-diabetes: effects of insulin deficiency and supplementation. J Lipid Res 34:1527-1534
    • (1993) J Lipid Res , vol.34 , pp. 1527-1534
    • Melki, S.A.1    Abumrad, N.A.2
  • 55
    • 0036025011 scopus 로고    scopus 로고
    • Streptozotocin induces lipolysis in rat adipocytes in vitro
    • Szkudelski T, Szkudelska K 2002 Streptozotocin induces lipolysis in rat adipocytes in vitro. Physiol Res 51:255-259
    • (2002) Physiol Res , vol.51 , pp. 255-259
    • Szkudelski, T.1    Szkudelska, K.2
  • 56
    • 0025217755 scopus 로고
    • Regulation of glucose transporter messenger RNA levels in rat adipose tissue by insulin
    • Sivitz WI, DeSautel SL, Kayano T, Bell GI, Pessin JE 1990 Regulation of glucose transporter messenger RNA levels in rat adipose tissue by insulin. Mol Endocrinol 4:583-588 (Pubitemid 120022317)
    • (1990) Molecular Endocrinology , vol.4 , Issue.4 , pp. 583-588
    • Sivitz, W.I.1    Desautel, S.L.2    Kayano, T.3    Bell, G.I.4    Pessin, J.E.5
  • 57
    • 0026450839 scopus 로고
    • Effect of streptozotocin-induced diabetes on GLUT-4 phosphorylation in rat adipocytes
    • Begum N, Draznin B 1992 Effect of streptozotocin-induced diabetes on GLUT-4 phosphorylation in rat adipocytes. J Clin Invest 90: 1254-1262
    • (1992) J Clin Invest , vol.90 , pp. 1254-1262
    • Begum, N.1    Draznin, B.2
  • 58
    • 0028086793 scopus 로고
    • GLUT-4 degradation rate: Reduction in rat adipocytes in fasting and streptozotocin-induced diabetes
    • Kim SS, Bae JW, Jung CY 1994 GLUT-4 degradation rate: reduction in rat adipocytes in fasting and streptozotocin-induced diabetes. Am J Physiol 267:E132-E139
    • (1994) Am J Physiol , vol.267
    • Kim, S.S.1    Bae, J.W.2    Jung, C.Y.3
  • 59
    • 34548103553 scopus 로고    scopus 로고
    • Hyperglycemia enhances adipogenic induction of lipid accumulation: Involvement of extracellular signal-regulated protein kinase 1/2, phosphoinositide 3-kinase/Akt, and peroxisome proliferator-activated receptor γ signaling
    • Chuang CC, Yang RS, Tsai KS, Ho FM, Liu SH 2007 Hyperglycemia enhances adipogenic induction of lipid accumulation: involvement of extracellular signal-regulated protein kinase 1/2, phosphoinositide 3-kinase/Akt, and peroxisome proliferator-activated receptor γ signaling. Endocrinology 148:4267-4275
    • (2007) Endocrinology , vol.148 , pp. 4267-4275
    • Chuang, C.C.1    Yang, R.S.2    Tsai, K.S.3    Ho, F.M.4    Liu, S.H.5
  • 61
    • 35649027860 scopus 로고    scopus 로고
    • Ghrelin gene-related peptides modulate rat white adiposity
    • Giovambattista A, Gaillard RC, Spinedi E 2008 Ghrelin gene-related peptides modulate rat white adiposity. Vitam Horm 77:171-205
    • (2008) Vitam Horm , vol.77 , pp. 171-205
    • Giovambattista, A.1    Gaillard, R.C.2    Spinedi, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.