메뉴 건너뛰기




Volumn 13, Issue 4, 2009, Pages 775-783

Exogenous ghrelin enhances endocrine and exocrine regeneration in pancreatectomized rats

Author keywords

Ghrelin; Pancreas; Pancreatectomy; Regeneration; Type 3 diabetes

Indexed keywords

GHRELIN;

EID: 67349108285     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11605-008-0778-2     Document Type: Article
Times cited : (20)

References (35)
  • 1
    • 0025238813 scopus 로고
    • Expression of reg protein in rat regenerating islets and its co-localization with insulin in the Beta cell secretory granules
    • K Terazono Y Uchiyama M Ide T Watanabe H Yonekura H Yamamoto H Okamoto 1990 Expression of reg protein in rat regenerating islets and its co-localization with insulin in the beta cell secretory granules Diabetologia 33 250 252 (Pubitemid 20136243)
    • (1990) Diabetologia , vol.33 , Issue.4 , pp. 250-252
    • Terazono, K.1    Uchiyama, Y.2    Ide, M.3    Watanabe, T.4    Yonekura, H.5    Yamamoto, H.6    Okamoto, H.7
  • 2
    • 0023860467 scopus 로고
    • Discordance of exocrine and endocrine growth after 90% pancreatectomy in rats
    • JS Brockenbrough GC Weir S Bonner-Weir 1988 Discordance of exocrine and endocrine growth after 90% pancreatectomy in rats Diabetes 37 232 236 (Pubitemid 18066610)
    • (1988) Diabetes , vol.37 , Issue.2 , pp. 232-236
    • Brockenbrough, J.S.1    Weir, G.C.2    Bonner-Weir, S.3
  • 4
    • 0027276885 scopus 로고
    • Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice
    • D Gu N Sarvetnick 1993 Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice Development 118 33 46 (Pubitemid 23191608)
    • (1993) Development , vol.118 , Issue.1 , pp. 33-46
    • Gu, D.1    Sarvetnick, N.2
  • 5
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
    • DOI 10.1038/nature02520
    • Y Dor J Brown OI Martinez DA Melton 2004 Adult pancreatic β cells are formed by self-duplication rather than stem-cell differentiation Nature 429 41 46 (Pubitemid 38620543)
    • (2004) Nature , vol.429 , Issue.6987 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Martinez, O.I.3    Melton, D.A.4
  • 7
    • 0033513455 scopus 로고    scopus 로고
    • Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats
    • G Xu DA Stoffers JF Habener S Bonner-Weir 1999 Exendin-4 stimulates both b-cell replication and neogenesis, resulting in increased β-cell mass and improved glucose tolerance in diabetic rats Diabetes 48 2270 2276 (Pubitemid 30395416)
    • (1999) Diabetes , vol.48 , Issue.12 , pp. 2270-2276
    • Xu, G.1    Stoffers, D.A.2    Habener, J.F.3    Bonner-Weir, S.4
  • 8
    • 0037342614 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats
    • DOI 10.2337/diabetes.52.3.741
    • JA Pospislik J Martin T Doty JA Ehses N Pamir FC Lynn S Piteau HU Demuth CH [tmp] McIntosh RA Pederson 2003 Dipeptidyl peptidase IV inhibitor treatment stimulates β-cell survival and islet neogenesis in streptozotocin-induced diabetic rats Diabetes 52 741 750 (Pubitemid 36323582)
    • (2003) Diabetes , vol.52 , Issue.3 , pp. 741-750
    • Pospisilik, J.A.1    Martin, J.2    Doty, T.3    Ehses, J.A.4    Pamir, N.5    Lynn, F.C.6    Piteau, S.7    Demuth, H.-U.8    McIntosh, C.H.S.9    Pederson, R.A.10
  • 9
    • 0034654497 scopus 로고    scopus 로고
    • Controlling TGF-beta signaling
    • J Massague YG Chen 2000 Controlling TGF-beta signaling Genes Dev 14 627 644
    • (2000) Genes Dev , vol.14 , pp. 627-644
    • Massague, J.1    Chen, Y.G.2
  • 10
    • 2642589990 scopus 로고    scopus 로고
    • Notochord repression of endodermal sonic hedgehog permits pancreas development
    • M Hebrok SK Kim DA Melton 1998 Notochord repression of endodermal sonic hedgehog permits pancreatic development Genes Dev 12 1705 1713 (Pubitemid 28299520)
    • (1998) Genes and Development , vol.12 , Issue.11 , pp. 1705-1713
    • Hebrok, M.1    Kim, S.K.2    Melton, D.A.3
  • 11
    • 0028916144 scopus 로고
    • Expression of immunoreactive activin A in fetal rat pancreas
    • M Furukawa Y Eto I Kojima 1995 Expression of immunoreactive activin A in fetal rat pancreas Endocrinol Jpn 42 63 68
    • (1995) Endocrinol Jpn , vol.42 , pp. 63-68
    • Furukawa, M.1    Eto, Y.2    Kojima, I.3
  • 12
  • 13
    • 0031916664 scopus 로고    scopus 로고
    • Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development
    • F Miralles P Czernichow R Scharfmann 1998 Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development Development 125 1017 1024 (Pubitemid 28171196)
    • (1998) Development , vol.125 , Issue.6 , pp. 1017-1024
    • Miralles, F.1    Czernichow, P.2    Scharfmann, R.3
  • 17
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • M Kojima H Hosoda Y Date M Nakazato H Matsuo K Kangawa 1999 Ghrelin is a growth-hormone-releasing acylated peptide from stomach Nature 402 656 660 (Pubitemid 129516334)
    • (1999) Nature , vol.402 , Issue.6762 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 18
    • 0037098974 scopus 로고    scopus 로고
    • The ghrelin cell: A novel developmentally regulated islet cell in the human pancreas
    • N Wierup H Svensson H Mulder F Sundler 2002 The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas Regul Pept 107 63 69
    • (2002) Regul Pept , vol.107 , pp. 63-69
    • Wierup, N.1    Svensson, H.2    Mulder, H.3    Sundler, F.4
  • 19
    • 1242318803 scopus 로고    scopus 로고
    • Ghrelin Is Expressed in a Novel Endocrine Cell Type in Developing Rat Islets and Inhibits Insulin Secretion from INS-1 (832/13) Cells
    • N Wierup S Yang RJ [tmp] McEvilly H Mulder F Sundler 2004 Ghrelin is expressed in a novel endocrine cell type in devoloping rat islets and inhibits insulin secretion from INS-1 (832/13) J Histochem Cytochem 52 301 310 (Pubitemid 38229096)
    • (2004) Journal of Histochemistry and Cytochemistry , vol.52 , Issue.3 , pp. 301-310
    • Wierup, N.1    Yang, S.2    McEvilly, R.J.3    Mulder, H.4    Sundler, F.5
  • 20
    • 1842422374 scopus 로고    scopus 로고
    • Circulating levels of ghrelin in human fetuses
    • DOI 10.1530/eje.0.1500405
    • N Wierup F Sundller 2004 Cirulating levels of ghrelin in human fetus Eur J Endocrinol 150 405 (Pubitemid 38443793)
    • (2004) European Journal of Endocrinology , vol.150 , Issue.3 , pp. 405
    • Wierup, N.1    Sundler, F.2
  • 21
    • 9444264700 scopus 로고    scopus 로고
    • Endogenous ghrelin in pancreatic istets resricts insulin release by attenuating Ca 2+ signaling in β-cells
    • K Dezaki H Hosoda 2004 Endogenous ghrelin in pancreatic istets resricts insulin release by attenuating Ca 2+ signaling in β-cells Diabetes 53 3142 3151
    • (2004) Diabetes , vol.53 , pp. 3142-3151
    • Dezaki, K.1    Hosoda, H.2
  • 23
    • 0020636495 scopus 로고
    • Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release
    • S Bonnes-Weir DF Trent GC Weir 1983 Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release J Clin Invest 71 1544 1553
    • (1983) J Clin Invest , vol.71 , pp. 1544-1553
    • Bonnes-Weir, S.1    Trent, D.F.2    Weir, G.C.3
  • 24
    • 0041965739 scopus 로고    scopus 로고
    • Betacellulin improves glucose metabolism by promoting conversion of intraislet precursor cells to beta-cells in streptozotocin-treated mice
    • L Li M Seno H Yamada I Kojima 2003 Betacellulin improves glucose metabolism by promoting conversion of intraislet precursor cells to β cells in streptozotocin-treated mice Am J Physiol Endocrinol Metab 285 E577 E583 (Pubitemid 37010836)
    • (2003) American Journal of Physiology - Endocrinology and Metabolism , vol.285
    • Li, L.1    Seno, M.2    Yamada, H.3    Kojima, I.4
  • 25
    • 1442265579 scopus 로고    scopus 로고
    • Islet transplantation as a treatment for diabetes-a work in progress
    • RP Rovertson 2000 Islet transplantation as a treatment for diabetes-a work in progress N Engl J Med 350 694 705
    • (2000) N Engl J Med , vol.350 , pp. 694-705
    • Rovertson, R.P.1
  • 28
    • 0023860467 scopus 로고
    • Discordance of exocrine and endocrine growth after 90% pancreatectomy in rats
    • JS Brockenbrough GC Weir S Bonner-Weir 1988 Discordance of exocrine and endocrine growth after 90% pancreatectomy in rats Diabetes 37 232 236 (Pubitemid 18066610)
    • (1988) Diabetes , vol.37 , Issue.2 , pp. 232-236
    • Brockenbrough, J.S.1    Weir, G.C.2    Bonner-Weir, S.3
  • 29
    • 15044357834 scopus 로고    scopus 로고
    • Ultrastructure of islet cells in human fetus
    • N Wierup F Sundler 2005 Ultrastructure of islet cells in human fetus Cell Tissue Res 319 423 428
    • (2005) Cell Tissue Res , vol.319 , pp. 423-428
    • Wierup, N.1    Sundler, F.2
  • 30
    • 33845534952 scopus 로고    scopus 로고
    • Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance
    • K Dezaki H Sone M Koizumi M Nakata M Kakei H Nagai H Hosoda K Kangawa T Yada 2006 Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance Diabetes 55 3486 3493
    • (2006) Diabetes , vol.55 , pp. 3486-3493
    • Dezaki, K.1    Sone, H.2    Koizumi, M.3    Nakata, M.4    Kakei, M.5    Nagai, H.6    Hosoda, H.7    Kangawa, K.8    Yada, T.9
  • 32
    • 33846435771 scopus 로고    scopus 로고
    • Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: Involvement of 3,5-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-kinase/Akt signaling
    • DOI 10.1210/en.2006-0266
    • R Granata F Settanni L Biancone L Trovato R Nano F Bertuzzi S Destefanis M Annunziata M Martinetti F Catapano C Ghè J Isgaard M Papotti E Ghigo G Muccioli 2007 Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3,5-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-Kinase/Akt signaling Endocrinology 148 512 529 (Pubitemid 46143157)
    • (2007) Endocrinology , vol.148 , Issue.2 , pp. 512-529
    • Granata, R.1    Settanni, F.2    Biancone, L.3    Trovato, L.4    Nano, R.5    Bertuzzi, F.6    Destefanis, S.7    Annunziata, M.8    Martinetti, M.9    Catapano, F.10    Ghe, C.11    Isgaard, J.12    Papotti, M.13    Ghigo, E.14    Muccioli, G.15
  • 35
    • 0038304457 scopus 로고    scopus 로고
    • Antagonism of ghrelin receptor reduces food intake and body weight gain in mice
    • DOI 10.1136/gut.52.7.947
    • A Asakawa A Inui T Kaga 2003 Antagonism of ghrelin receptor reduces food intake and body weight gain in mice Gut 52 547 552 (Pubitemid 36765284)
    • (2003) Gut , vol.52 , Issue.7 , pp. 947-952
    • Asakawa, A.1    Inui, A.2    Kaga, T.3    Katsuura, G.4    Fujimiya, M.5    Fujino, M.A.6    Kasuga, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.