Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults

Immunogenetics

Volumn 62, Issue 6, 2010, Pages 345-356

  Phawong, Chintana ^a   Ouma, Collins ^b,c   Tangteerawatana, Piyatida ^a,d   Thongshoob, Jarinee ^a   Were, Tom ^b   Mahakunkijcharoen, Yuvadee ^a   Wattanasirichaigoon, Duangrurdee ^e   Perkins, Douglas Jay ^b,f   Khusmith, Srisin ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c MASENO UNIVERSITY   (Kenya)

^d SRINAKHARINWIROT UNIVERSITY   (Thailand)

^e MAHIDOL UNIVERSITY   (Thailand)

^f UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

Haplotype; IL12B; P. falciparum; Severe malaria; Single nucleotide polymorphism

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12P40; INTERLEUKIN 12;

ADULT; AGED; ARTICLE; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DISEASE SEVERITY; DNA EXTRACTION; DNA POLYMORPHISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE AMPLIFICATION; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALARIA; NONHUMAN; PARASITEMIA; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; THAILAND; 3' UNTRANSLATED REGION; ADOLESCENT; BLOOD; FEMALE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MALARIA FALCIPARUM; MALE; MIDDLE AGED; PROMOTER REGION;

PLASMODIUM FALCIPARUM;

3' UNTRANSLATED REGIONS; ADOLESCENT; ADULT; AGED; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-12; INTERLEUKIN-12 SUBUNIT P40; MALARIA, FALCIPARUM; MALE; MIDDLE AGED; PARASITEMIA; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC;

EID: 77953153281     PISSN: 00937711     EISSN: 14321211     Source Type: Journal    
DOI: 10.1007/s00251-010-0439-y     Document Type: Article

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