Affinity maturation of a TNFα-binding affibody molecule by Darwinian survival selection

Biotechnology and Applied Biochemistry

Volumn 55, Issue 3, 2010, Pages 111-120

  Löfdahl, Per Åke ^a   Nygren, Per Åke ^a  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

lactamase; Affibody affinity protein; Affinity maturation; Protein fragment complementation assay (PCA); Tumour necrosis factor (TNF )

Indexed keywords

AFFINITY MATURATION; LACTAMASES; NECROSIS FACTORS; PROTEIN AFFINITY; PROTEIN FRAGMENTS;

BIOCHEMICAL ENGINEERING; BIOSENSORS; CELL CULTURE; GENETIC ENGINEERING; GLYCOPROTEINS; LIQUIDS; MACROPHAGES; MOLECULES; RATE CONSTANTS; TARGETS; TUMORS;

PROTEINS;

AFFIBODY MOLECULE; BETA LACTAMASE; PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; BIOSENSOR; CLONE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; LIQUID CULTURE; NONHUMAN; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FRAGMENT COMPLEMENTATION ASSAY; COMBINATORIAL CHEMISTRY; GENETIC PROCEDURES; GENETIC SELECTION; METABOLISM;

BIOSENSING TECHNIQUES; COMBINATORIAL CHEMISTRY TECHNIQUES; SELECTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77953131705     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20090274     Document Type: Article

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