Glutathione S-transferase M1 polymorphism and breast cancer susceptibility: A meta-analysis involving 46, 281 subjects

Breast Cancer Research and Treatment

Volumn 121, Issue 3, 2010, Pages 703-708

  Qiu, Li Xin ^a   Yuan, Hui ^b   Yu, Ke Da ^a   Mao, Chen ^c   Chen, Bo ^d   Zhan, Ping ^e   Xue, Kai ^a   Zhang, Jian ^a   Hu, Xi Chun ^a  

^a FUDAN UNIVERSITY   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

^d NANJING MEDICAL UNIVERSITY   (China)

^e NANJING CHEST HOSPITAL   (China)

Author keywords

Breast cancer; GSTM1; Meta analysis; Polymorphism; Susceptibility

Indexed keywords

GLUTATHIONE TRANSFERASE M1;

ARTICLE; BREAST CANCER; CANCER RISK; ETHNICITY; EVIDENCE BASED MEDICINE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; POPULATION RESEARCH; POSTMENOPAUSE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR;

BREAST NEOPLASMS; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GLUTATHIONE TRANSFERASE; HUMANS; POLYMORPHISM, GENETIC;

EID: 77953120132     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-009-0636-2     Document Type: Article

References (69)

1. Parkin DM, Bray F, Ferlay J, Pisani P (2005) Global cancer statistics 2002. CA. Cancer J Clin 55: 74-108
2. Lichtenstein P, Holm NV, Verkasalo PK (2000) Environmental and heritable factors in the causation of cancer. N Engl J Med 343: 78-85
3. Yager JD, Davidson NE (2006) Estrogen carcinogenesis in breast cancer. N Engl J Med 354: 270-282
4. Yu KD, Di GH, Fan L, Wu J, Hu Z, Shen ZZ, Huang W, Shao ZM (2009) A functional polymorphism in the promoter region of GSTM1 implies a complex role for GSTM1 in breast cancer. FASEB J 23: 2274-2287
5. ZhongS,WyllieAH,BarnesD,WolfCR,SpurrNK(1993) RelationshipbetweentheGSTM1geneticpolymorphismandsusceptibility-bladder, breastandcoloncancer.Carcinogenesis14:1821-1824(Pubitemid23290894)
6. Kelsey KT, Hankinson SE, Colditz GA, Springer K, GarciaClosas M, Spiegelman D, Manson JE, Garland M, Stampfer MJ, Willett WC, Speizer FE, Hunter DJ (1997) Glutathione S-transferase class mu deletion polymorphism and breast cancer: results from prevalent versus incident cases. Cancer Epidemiol Biomarkers Prev 6: 511-515
7. Ambrosone CB, Coles BF, Ereudenheim JL, Shields PG (1999) Glutathione-S-transferase (GSTM1) genetic polymorphisms do not affect human breast cancer risk, regardless of dietary antioxidants. J Nutr 129: 565S-568S
8. CharrierJ,MaugardCM,LeMevelB,BignonYJ(1999) AllelotypeinfluenceatglutathioneS- transferaseM1locusonbreastcancersusceptibility.BrJCancer79:346- 353(Pubitemid29002306)
9. Garcia-Closas M, Kelsey KT, Hankinson SE, Spiegelman D, Springer K, Willett WC, Speizer FE, Hunter DJ (1999) Glutathione S-transferase mu and theta polymorphisms and breast cancer susceptibility. J Natl Cancer Inst 91: 1960-1964
10. HelzlsouerKJ,SelminO,HuangHY,StricklandPT,HoffmanS,AlbergAJ,WatsonM, ComstockGW,BellD(1998)AssociationbetweenglutathioneS-transferaseMl,P1, andT1geneticpolymorphismsanddevelopmentofbreastcancer.JNatlCancerInst90: 512-518(Pubitemid28182544)
11. Curran JE, Weinstein SR, Griffiths LR (2000) Polymorphisms of glutathione S-transferase genes (GSTM1, GSTP1 and GSTT1) and breast cancer susceptibility. Cancer Lett 153: 113-120
12. Millikan R, Pittman G, Tse CK, Savitz DA, Newman B, Bell D (2000) Glutathione S-transferases M1, T1, and P1 and breast cancer. Cancer Epidemiol Biomarkers Prev 9: 567-573
13. Rundle A, Tang D, Zhou J, Cho S, Perera F (2000) The association between glutathione S-transferase M1 genotype and polycyclic aromatic hydrocarbon-DNA adducts in breast tissue. Cancer Epidemiol Biomarkers Prev 9: 1079-1085
14. Gudmundsdottir K, Tryggvadottir L, Eyfjord JE (2001) GSTM1, GSTT1, and GSTP1 genotypes in relation to breast cancer risk and frequency of mutations in the p53 gene. Cancer Epidemiol Biomarkers Prev 10:1169-1173
15. Krajinovic M, Ghadirian P, Richer C, Sinnett H, Gandini S, Perret C, Lacroix A, Labuda D, Sinnett D (2001) Genetic susceptibility to breast cancer in French-Canadians: role of carcinogen-metabolizing enzymes and gene-environment interactions. Int J Cancer 92: 220-225 (Pubitemid 32225373)
16. MitrunenK,JourenkovaN,KatajaV,EskelinenM,KosmaVM,BenhamouS,VainioH, UusitupaM,HirvonenA(2001)GlutathioneS-transferaseM1,M3,P1, andT1geneticpolymorphismsandsusceptibility-breastcancer. CancerEpidemiolBiomarkersPrev10:229-236(Pubitemid34288534)
17. XiongP,BondyML,LiD,ShenH,WangLE,SingletarySE,SpitzMR,WeiQ(2001) Sensitivity-benzo(a) pyrenediolepoxideassociatedwithriskofbreastcancerinyoungwomenandmodulationbyglu tathioneS-transferasepolymorphisms:acase-controlstudy.CancerRes61: 8465-8469(Pubitemid33131126)
18. Dialyna IA, Arvanitis DA, Spandidos DA (2001) Genetic polymorphisms and transcriptional pattern analysis of CYP1 A1, AhR, GSTM1, GSTP1 and GSTT1 genes in breast cancer. Int J Mol Med 8:79-87
19. de Amorim L, Rossini A, Mendonca G, Lotsch P, de Almeida Simao T, de Moura Gallo C, Pinto L (2002) CYP1A1, GSTM1, and GSTT1. polymorphisms and breast cancer risk in Brazilian women. Cancer Lett 181:179-186
20. Siegelmann-Danieli N, Buetow KH (2002) Significance of genetic variation at the glutathione S-transferase M1 and NAD(P)H:quinone oxidoreductase 1. detoxification genes in breast cancer development, Oncology 62:39-45 (Pubitemid 34124224)
21. Wu FY, Lee YJ, Chen DR, Kuo HW (2002) Association of DNAprotein crosslinks and breast cancer. Mutat Res 501: 69-78 (Pubitemid 34270652)
22. Zheng T, Holford TR, Zahm SH, Owens PH, Boyle P, Zhang Y, Wise JP Sr, Stephenson LP, Ali-Osman F (2002) Cigarette smoking, glutathione-s-transferase M1 and t1 genetic polymorphisms, and breast cancer risk (United States). Cancer Causes Control 13:637-645 (Pubitemid 35001771)
23. Zheng W, Wen WQ, Gustafson DR, Gross M, Cerhan JR, Folsom AR (2002) GSTM1 and GSTT1 polymorphisms and postmenopausal breast cancer risk. Breast Cancer Res Treat 74:9-16 (Pubitemid 34734591)
24. Matheson MC, Stevenson T, Akbarzadeh S, Propert DN (2002) GSTT1 null genotype increases risk of premenopausal breast cancer. Cancer Lett 181:73-79 (Pubitemid 34310664)
25. Li D, Walcott FL, Chang P (2002) Genetic and environmental determinants on tissue response to in vitro carcinogen exposure and risk of breast cancer. Cancer Res 62:4566-4570
26. Khedhaier A, Remadi S, Corbex M (2003) Glutathione S-transferases (GSTT1 and GSTM1) gene deletions in Tunisians: susceptibility and prognostic implications in breast carcinoma. Br J Cancer 89: 1502-1507 (Pubitemid 37386606)
27. Zhu J, Chang P, Bondy ML, Sahin AA, Singletary SE, Takahashi S, Shirai T, Li D (2003) Detection of 2-amino-1-methyl-6-phenylimidazo[4, 5-b]-pyridine-DNA adducts in normal, breast tissues and risk of breast cancer. Cancer Epidemiol Biomarkers Prev 12:830-837
28. Egan KM, Cai Q, Shu XO, Jin F, Zhu TL, Dai Q, Gao YT, Zheng W (2004) Genetic polymorphisms in GSTM1, GSTP1, and GSTT1 and the risk for breast cancer: results from the Shanghai Breast Cancer Study and meta-analysis. Cancer Epidemiol Biomarkers Prev 13:197-204
29. McCarty KM, Santella RM, Steck SE, Cleveland RJ, Ahn J, Ambrosone CB, North K, Sagiv SK, Eng SM, Teitelbaum SL, Neugut AI, Gammon MD (2009) PAH-DNA adducts, cigarette smoking, GST polymorphisms, and breast cancer risk. Environ Health Perspect 117:552-558
30. Medeiros R, Soares R, Vasconcelos A, Schmitt F, Lopes C (2004) Glutathione S-transferase genotype GSTM1 as a predictor of elevated angiogenic phenotype in patients with early onset breast cancer. Angiogenesis 7:53-58 (Pubitemid 39127771)
31. Park SK, Yim DS, Yoon KS (2004) Combined effect of GSTM1, GSTT1, and COMT genotypes in individual breast cancer risk. Breast Cancer Res Treat 88:55-62
32. Sarmanova J, Susova S, Gut I, Mrhalova M, Kodet R, Adamek J, Roth Z, Soucek P (2004) Breast cancer: role of polymorphisms in biotransformation enzymes. Eur J Hum Genet 12: 848-854 (Pubitemid 39406070)
33. van der Hel OL, Peeters PH, Hein DW (2004) GSTM1 null genotype, red meat consumption and breast cancer risk (The Netherlands). Cancer Causes Control 15:295-303
34. Gago-Dominguez M, Castelao JE, Sun CL, Van Den Berg D, Koh WP, Lee HP, Yu MC (2004) Marine n-3 fatty acid intake, glutathione S-transferase polymorphisms and breast cancer risk in post-menopausal Chinese women in Singapore. Carcinogenesis 25:21.43-21.47
35. Roodi N, Dupont WD, Moore JH, Pari FF (2004) Association of homozygous wild-type glutathione S-transferase M1 genotype with increased breast cancer risk. Cancer Res 64:1233-1236
36. Ceschi M, Sun CL, Van Den Berg D, Koh WP, Yu MC, ProbstHensch N (2005) The effect of cyclin D1. (CCND1.) G870Apolymorphism on breast cancer risk is modified by oxidative stress among Chinese women in Singapore. Carcinogenesis 26:1457-1464
37. Chacko P, Joseph T, Mathew BS, Rajan B, Pillai MR (2005) Role of xenobiotic metabolizing gene polymorphisms in breast cancer susceptibility and treatment outcome. Mutat Res 581:153-163
38. Cheng TC, Chen ST, Huang CS, Fu YP, Yu JC, Cheng CW, Wu PE, Shen CY (2005) Breast cancer risk associated with genotype polymorphism of the catechol estrogen-metabolizing genes: a multigenic study on cancer susceptibility. Int J Cancer 113: 345-353
39. Linhares JJ, Da Silva ID, De Souza NC, Noronha EC, Ferraro O, De Carvalho CV, Baracat EC, Baracat FF (2005) Genetic polymorphism of GSTM1in women with breast cancer and interact with reproductive history and several clinical pathologies. Biol Res 38:273-281.
40. Van der Hel OL, Bueno-de-Mesquita HB, van Gils CH, Roest M, Slothouber B, Grobbee DE, Peeters PH (2005) Cumulative genetic defects in carcinogen, metabolism may increase breast cancer risk (The Netherlands). Cancer Causes Control 16:675-681
41. Chang TW, Wang SM, Guo YL, Tsai PC, Huang CJ, Huang W (2006) Glutathione S-transferase polymorphisms associated with risk of breast cancer in southern Taiwan. Breast 15:754-761
42. Wu SH, Tsai SM, Hou MF, Lin HS, Hou LA, Ma H, Lin JT, Yeh FL, Tsai LY (2006) Interaction of genetic polymorphisms in cytochrome P450 2E1 and glutathione S-transferase M1 to breast cancer in Taiwanese woman without smoking and drinking habits. Breast Cancer Res Treat 100:93-98
43. Edvardsen H, Kristensen VN, Grenaker Alnaes GI, Bohn M, Erikstein B, Heiland A, Borresen-Dale AL, Fossa SD (2007) Germline glutathione S-transferase variants in breast cancer: relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy. Int J Radiat Oncol Biol Phys 67:1163-1171
44. Nordgard SH, Ritchie MD, Jensrud SD, Motsinger AA, Alnaes GI, Lemmon G, Berg M, Geisler S, Moore JH, Lonning PE, Borresen-Dale AL, Kristensen VN (2007) ABCB1 and GST polymorphisms associated with TP53 status in breast cancer. Pharmacogenet Genomics 17:127-136
45. Spurdle AB, Chang JH, Byrnes GB, Chen X, Dite GS, McCredie MR, Giles GG, Southey MC, Chenevix-Trench G, Hopper JL (2007) A systematic approach to analysing gene-gene interactions: polymorphisms at the microsomal epoxide hydrolase EPHX and glutathione S-transferase GSTM1, GSTT1, and GSTP1. loci and breast cancer risk. Cancer Epidemiol Biomarkers Prev 16:769-774
46. Steck SE, Gaudet MM, Britton JA, Teitelbaum SL, Terry MB, Neugut AI, Santella RM, Gammon MD (2007) Interactions among GSTM1, GSTT1 and GSTP1 polymorphisms, cruciferous vegetable intake and breast cancer risk. Carcinogenesis 28:1954-1959
47. Kadouri L, Kote-Jarai Z, Hubert A, Baras M, Abeliovich D, Hamburger T, Peretz T, Eeles RA (2008) Glutathione-S-transferase Ml, T1 and P1 polymorphisms, and breast cancer risk, in BRCA1/2 mutation carriers. Br J Cancer 98: 2006-2010
48. Rajkumar T, Samson M, Rama R, Sridevi V, Mahji. U, Swaminathan R, Nancy NK (2008) TGFbeta1 (Leu10Pro), p53 (Arg72Pro) can predict for increased risk for breast cancer in south Indian women and TGFbeta1 Pro (Leu10Pro) allele predicts response to neo-adjuvant chemo-radiotherapy. Breast Cancer Res Treat 112: 81-87
49. Sakoda LC, Blackston CR, Xue K, Doherty JA, Ray RM, Lin MG, Stalsberg H, Gao DL, Feng Z, Thomas DB, Chen C (2008) Glutathione S-transferase M1 and P1 polymorphisms and risk of breast cancer and fibrocystic breast conditions in Chinese women. Breast Cancer Res Treat 109:143-155
50. Saxena A, Dhillon VS, Raish M, Asim M, Rehman S, Shukla NK, Deo SV, Ara A, Husain SA (2009) Detection and relevance of germline genetic polymorphisms in glutathione S-transferases (GSTs) in breast cancer patients from northern Indian population. Breast Cancer Res Treat 115:537-543
51. Syamala VS, Sreeja L, Syamala V, Raveendran PB, Balakrishnan R, Kuttan R, Ankathil R (2008) Influence of germline polymorphisms of GSTT1, GSTM1, and GSTP1 in familial versus sporadic breast cancer susceptibility and survival. Fam Cancer 7:213-220
52. Torresan C, Oliveira MM, Torrezan GT, de Oliveira SF, Abuazar CS, Losi-Guembarovski R, Lima RS, Urban CA, Cavalli IJ, Ribeiro EM (2008) Genetic polymorphisms in oestrogen metabolic pathway and breast cancer: a positive association with combined CYP/GST genotypes. Clin Exp Med 8:65-71
53. Unlü A, Ates NA, Tamer L, Ates C (2008) Relation of glutathione S-transferase T1, M1 and P1 genotypes and breast cancer risk. Cell Biochem Funct 26: 643-647
54. Van Emburgh BO, Hu JJ, Levine EA, Mosley LJ, Perrier ND, Freimanis RI, Allen GO, Rubin P, Sherrill GB, Shaw CS, Carey LA, Sawyer LR, Miller MS (2008) Polymorphisms in CYP1B1, GSTM1, GSTT1 and GSTP1, and susceptibility to breast cancer. Oncol Rep 19:1311-1321
55. Reding KW, Weiss NS, Chen C, Li CI, Carlson CS, Wilkerson HW, Farm FM, Thummel KE, Daling JR, Malone KE (2009) Genetic polymorphisms in the catechol estrogen metabolism pathway and breast cancer risk. Cancer Epidemiol Biomarkers Prev 18:1461-1467
56. The MARIE-GENICA Consortium on Genetic Susceptibility for Menopausal Hormone Therapy Related Breast Cancer Risk (2009) Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women. Breast Cancer Res Treat. doi: 10.1007/s 10549-009-0407-410
57. Sgambato A, Campisi B, Zupa A (2002) Glutathione S-transferase (GST) polymorphisms as risk factors for cancer in a highly homogeneous population from southern Italy. Anticancer Res 22:3647-3652
58. Bailey LR, Roodi N, Verrier CS, Yee CJ, Dupont WD, Pari FF (1998) Breast cancer and CYPIA1, GSTM1, and GSTT1 polymorphisms: evidence of a lack of association in Caucasians and African Americans. Cancer Res 58: 65-70
59. McCready D, Aronson KJ, Chu W, Fan W, Vesprini D, Narod SA (2004) Breast tissue organochlorine levels and metabolic genotypes in relation to breast cancer risk Canada. Cancer Causes Control 15:399-418
60. Cochran WG (1954) The combination of estimates from different experiments. Biometrics 10:101-129
61. Mantel N, Haenszel W (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J Natl. Cancer Inst 22:719-748
62. DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7:177-188
63. Tobias A (1999) Assessing the influence of a single study in the meta-analysis estimate. Stata Tech Bull 8: 15-17
64. Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629-634
65. Salinas AE, Wong MG (1999) Glutathione S-transferases-a review. Curr Med Chem 6:279-309
66. Hirschhorn JN, Lohmueller K, Byrne E (2002) A comprehensive review of genetic association studies. Genet Med 4:45-61.
67. WacholderS,ChanockS,Garcia-ClosasM(2004) Assessingtheprobabilitythatapositivereportisfalse: anapproachformolecularepidemiologystudies.JNatlCancerInst96:434- 442(Pubitemid38443646)
68. Kaaks R, Rinaldi S, Key TJ (2005) Postmenopausal serum androgens, oestrogens and breast cancer risk: the European prospective investigation into cancer and nutrition. Endocr Relat Cancer 12:1071-1082 (Pubitemid 41815798)
69. Key T, Appleby P, Barnes I, Reeves G (2002) Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies. J Natl Cancer Inst 94:606-616