Glutathione S-transferase mu and theta polymorphisms and breast cancer susceptibility

Journal of the National Cancer Institute

Volumn 91, Issue 22, 1999, Pages 1960-1964

  García Closas, Montserrat ^a   Kelsey, Karl T ^b,c   Hankinson, Susan E ^e   Spiegelman, Donna ^e   Springer, Kathryn ^e   Willett, Walter C ^e   Speizer, Frank E ^e   Hunter, David J ^d  

^a NATIONAL CANCER INSTITUTE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD CENTER FOR CANCER PREVENTION   (United States)

^d CHANNING LABORATORY   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE;

ADULT; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER RISK; CANCER SUSCEPTIBILITY; ENZYME ANALYSIS; FEMALE; GENE DELETION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REGRESSION ANALYSIS;

EID: 0344339711     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/91.22.1960     Document Type: Article

References (25)

1. Madigan MP, Ziegler RG, Benichou J, Byrne C, Hoover RN. Proportion of breast cancer cases in the United States explained by well-established risk factors. J Natl Cancer Inst 1995;87:1681-5.
2. Sturgeon SR, Schairer C, Gail M, McAdams M, Brinton LA, Hoover RN. Geographic variation in mortality from breast cancer among white women in the United States. J Natl Cancer Inst 1995;87:1846-53.
3. Kelsey JL, Horn-Ross PL. Breast cancer: magnitude of the problems and descriptive epidemiology. Epidemiol Rev 1993;15:7-16.
4. Davis DL, Bradlow HL, Wolff M, Woodruff T, Hoel DG, Anton-Culver H. Medical hypothesis: xenoestrogens as preventable causes of breast cancer. Environ Health Perspect 1993; 101:372-7.
5. Raunio H, Husgafvel-Pursiainen K, Anttila S, Hietanen E, Hirvonen A, Pelkonen O. Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility - a review. Gene 1995;159:113-21.
6. Hayes JD, Pulford DJ. The glutathione S-transferase supergene family: regulation of GST and contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 1995;30:445-600.
7. Russo J, Russo IH. Biological and molecular bases of mammary carcinogenesis. Lab Invest 1987;57:112-37.
8. Rebbeck TR. Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility. Cancer Epidemiol Biomarkers Prev 1997;6: 733-43.
9. Hallier E, Langhof T, Dannappel D, Leutbecher M, Schröder K, Goergens HW, et al. Polymorphisms of glutathione conjugation of methyl bromide, ethylene oxide and dichloromethane in human blood: influence on the induction of sister chromatid exchanges (SCE) in lymphocytes. Arch Toxicol 1993;67:173-8.
10. Wiencke JK, Pemble S, Ketterer B, Kelsey KT. Gene deletion of glutathione S-transferase theta: correlation with induced genetic damage and potential role in endogenous mutagenesis. Cancer Epidemiol Biomarkers Prev 1995;4: 253-9.
11. Norppa H, Hirvonen A, Jeventaus H, Uuskla M, Tasa G, Ojajarvi A, et al. Role of GSTT1 and GSTM1 genotypes in determining individual sensitivity to sister chromatid exchange induction by diepoxybutane in cultured human lymphocytes. Carcinogenesis 1995;16:1261-4.
12. Wiencke JK, Kelsey KT, Lamela RA, Toscano WA Jr. Human glutathione S-transferase deficiency as marker of susceptibility to epoxide-induced cytogenetic damage. Cancer Res 1990; 50:1585-90.
13. van Poppel G, de Vogel N, van Balderen PJ, Kok FJ. Increased cytogenetic damage in smokers deficient in glutathione 5-transferase isoenzyme mu. Carcinogenesis 1992;13: 303-5.
14. Thier R, Taylor JB, Pemble SE, Humphreys WG, Persmark M, Ketterer B, et al. Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes. Proc Natl Acad Sci U S A 1993;90: 8576-80.
15. Hallier E, Schröder KR, Asmuth K, Dommermuth A, Aust B, Goergens HW. Metabolism of dichloromethane (méthylène chloride) to formaldehyde in human erythrocytes: influence of polymorphism of glutathione transferase theta (GST T1-I). Arch Toxicol 1994;68:423-7.
16. Guengerich FP, Thier R, Persmark M, Taylor JB, Pemble SE, Ketterer B. Conjugation of carcinogens by theta class glutathione s-transferases: mechanisms and relevance to variations in human risk. Pharmacogenetics 1995;5 Spec No:S103-7.
17. Ambrosone CB, Freudenheim JL, Graham S, Marshall JR, Vena JE, Brasure JR, et al. Cytochrome P4501A1 and glutathione S-transferase (M1) genetic polymorphisms and postmenopausal breast cancer risk. Cancer Res 1995;55:3483-5.
18. Zhong S, Wyllie AH, Barnes D, Wolf CR, Spurr NK. Relationship between the GSTM1 genetic polymorphisms and susceptibility to bladder, breast and colon cancer. Carcinogenesis 1993;14:1821-4.
19. Bailey LR, Roodi N, Verrier CS, Yee CJ, Dupont WD, Parl FF. Breast cancer and CYPIA1, GSTM1, and GSTT1 polymorphisms: evidence of a lack of association in Caucasians and African-Americans. Cancer Res 1998;58: 65-70.
20. Helzlsouer KJ, Selmin O, Huang HY, Strickland PT, Hoffman S, Alberg AJ, et al. Association between glutathione S-transferase M1, P1, and T1 genetic polymorphisms and development of breast cancer. J Natl Cancer Inst 1998;90:512-8.
21. Charrier J, Maugard CM, Le Mevel B, Bignon YJ. Allelotype influence at glutathione S-transferase M1 locus on breast cancer susceptibility. Br J Cancer 1999;79:346-53.
22. Kelsey KT, Hankinson SE, Colditz G, Springer K, Garcia-Closas M, Spiegelman D, et al. Glutathione S-transferase class mu deletion polymorphism and breast cancer: results from prevalent versus incident cases. Cancer Epidemiol Biomarkers Prev 1997;6:511-5.
23. Belanger CF, Hennekens CH, Rosner B, Speizer FE. The Nurses' Health Study. Am J Nurs 1978;78:1039-40.
24. Hunter DJ, Hankinson SE, Hough H, Gertig DM, Garcia-Closas M, Spiegelman D, et al. A prospective study of NAT2 acetylation genotype, cigarette smoking, and risk of breast cancer. Carcinogenesis 1997;18:2127-32.
25. Cheng TJ, Christiani DC, Xu X, Wain JC, Wiencke JK, Kelsey KT. Glutathione S-transferase μ genotype, diet, and smoking as determinants of sister chromatid exchange frequency in lymphocytes. Cancer Epidemiol Biomarkers Prev 1995;4:535-42.