Breast cancer risk associated with genotype polymorphism of the catechol estrogen-metabolizing genes: A multigenic study on cancer susceptibility

International Journal of Cancer

Volumn 113, Issue 3, 2005, Pages 345-353

  Cheng, Ting Chih ^a   Chen, Shou Tung ^b   Huang, Chiun Sheng ^c   Fu, Yi Ping ^a   Yu, Jyh Cherng ^d   Cheng, Chun Wen ^a,e   Wu, Pei Ei ^a   Shen, Chen Yang ^a,f  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^e CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^f ACADEMIA SINICA   (Taiwan)

Author keywords

Breast cancer; Catechol estrogen; Estrogen; Molecular epidemiology; Polymorphism

Indexed keywords

1,4 BENZOQUINONE; CATECHOL ESTROGEN; CATECHOL METHYLTRANSFERASE; DOUBLE STRANDED DNA; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; SEMIQUINONE; SULFOTRANSFERASE;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER RISK; CANCER SUSCEPTIBILITY; CONJUGATION; CONTROLLED STUDY; DETOXIFICATION; DNA STRAND BREAKAGE; FEMALE; GENE FUNCTION; GENETIC POLYMORPHISM; GENETIC RECOMBINATION; GENOTYPE; GLUCURONIDATION; HUMAN; HUMAN EXPERIMENT; MAJOR CLINICAL STUDY; MENARCHE; METHYLATION; NUCLEOTIDE METABOLISM; OXIDATION; PREGNANCY; PRIORITY JOURNAL; RISK ASSESSMENT; SULFATION;

ADULT; AGED; AGED, 80 AND OVER; ARYLSULFOTRANSFERASE; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CASE-CONTROL STUDIES; CATECHOL O-METHYLTRANSFERASE; DNA; DNA REPAIR; ESTROGENS, CATECHOL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; HUMANS; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS; SUPEROXIDE DISMUTASE; TAIWAN; TUMOR MARKERS, BIOLOGICAL;

EID: 11144304064     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20630     Document Type: Article

References (49)

1. Hulka BS, Stark AT. Breast cancer: cause and prevention. Lancet 1995;346:883-7.
2. Kelsey JL, Gammon MD, John EM. Reproductive factors and breast cancer. Epidemiol Rev 1993;15:36-47.
3. Pike MC, Spicer DV, Dahmoush L, Press MF. Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk. Epidemiol Rev 1993;15:17-35.
4. Dickson RB, Stancel GM. Estrogen receptor-mediated processes in normal and cancer cells. J Natl Cancer Inst Monogr 2000;27:135-45.
5. Gruber CJ, Tschugguel W, Schneeberger C, Huber JC. Production and actions of estrogens. N Engl J Med 2002;346:340-52.
6. Yager JD. Endogenous estrogens as carcinogens through metabolic activation. J Natl Cancer Inst Monogr 2000;27:67-73.
7. Cavalieri EL, Stack DE, Devanesan PD, Todorovic R, Dwivedy I, Higginbotham S, Johansson SL, Patil KD, Gross ML, Gooden JK, Ramanathan R, Cerny RL, et al. Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators. Proc Natl Acad Sci USA 1997;94:10937-42.
8. Yager JD, Liehr JG. Molecular mechanisms of estrogen carcinogenesis. Ann Rev Pharmacol Toxicol 1996;36:203-32.
9. Friedberg EC, Walker GC, Siede W. DNA repair and mutagenesis. Washington, DC: ASM Press, 1995. 1-58.
10. Cavalieri E, Frenkel K, Liehr JG, Rogan E, Roy D. Estrogens as endogenous genotoxic agents-DNA adducts and mutations. J Natl Cancer Inst Monogr 2000;27:75-93.
11. Raftogianis R, Creveling C, Weinshilboum R, Weisz J. Estrogen metabolism by conjugation. J Natl Cancer Inst Monogr 2000;27:113-24.
12. Fu YP, Yu JC, Cheng TC, Lou MA, Hsu GC, Wu CY, Chen ST, Wu HS, Wu PE, Shen CY. Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: a multigenic study on cancer susceptibility. Cancer Res 2003;63:2440-6.
13. Bau DT, Fu YP, Chen ST, Cheng TC, Yu JC, Wu PE, Shen CY. Breast cancer risk and the DNA double-strand break end-joining capacity of non-homologous end-joining genes are affected by BRCA1. Cancer Res 2004;64:5013-9.
14. Yang PS, Yang TL, Liu CL, Wu CW, Shen CY. A case-control study of breast cancer in Taiwan. Br J Cancer 1997;75:752-6.
15. Lo YL, Yu JC, Huang CS, Tseng SL, Chang TM, Chang KJ, Wu CW, Shen CY. Allelic loss of the BRCA1 and BRCA2 genes and other regions on 17q and 13q in breast cancer among women from Taiwan (area of low incidence but early onset). Int J Cancer 1998;79:580-587.
16. Huang CS, Chern HD, Chang KJ, Cheng CW, Hsu SM, Shen CY. Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic study on cancer susceptibility. Cancer Res 1999;59:4870-5.
17. Lou MA, Tseng SL, Chang SF, Yue CT, Chang BL, Chou CH, Yang SL, Teh BH, Wu CW, Shen CY. Novel patterns of p53 abnormality in breast cancer from Taiwan: experience from a low incidence area. Br J Cancer 1997;75:746-51.
18. Shen CY, Yu JC, Lo YL, Kuo CH, Yue CT, Jou YS, Huang CS, Lung JC, Wu CW. Genome-wide search for loss of heterozygosity using laser capture microdissected tissue of breast carcinoma - an implication for mutator phenotype and breast cancer pathogenesis. Cancer Res 2000;60:3884-92.
19. Lung JC, Chu JS, Yu JC, Yue CT, Lo YL, Shen CY, Wu CW. Aberrant expression of cell cycle regulator cyclin D1 in breast cancer is related to chromosomal genomic instability. Genes Chromosomes Cancer 2002;34:276-84.
20. Huang CS, Chern HD, Shen CY, Hsu SM, Chang KJ. Association between N-acetyltransferase 2 (NAT2) genetic polymorphism and development of breast cancer in post-menopausal Chinese women in Taiwan, an area of great increase in breast cancer incidence. Int J Cancer 1999;82:175-9.
21. Dawling S, Roodi N, Mernaugh RL, Wang X, Parl FF. Catechol-O- methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms. Cancer Res 2001;61:6716-22.
22. Raftogianis RB, Wood TC, Otterness DM, Van Loon JA, Weinshilboum RM. Phenol sulfotransferase pharmacogenetics in humans: association of common SULT1A1 alleles with TS PST phenotype. Biochem Biophys Res Commun 1997;239:298-304.
23. Guillemette C, Millikan RC, Newman B, Housman DE. Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans. Cancer Res 2000;60:950-6.
24. Ambrosone CB, Freudenheim JL, Thompson PA, Bowman E, Vena JE, Marshall JR, Graham S, Laughlin R, Nemoto T, Shields PG. Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer. Cancer Res 1999;59:602-6.
25. Brockmoller J, Kerb R, Drakoulis N, Staffeldt B, Roots I. Glutathione S-transferase M1 and its variants A and B as host factors of bladder cancer susceptibility: a case-control study. Cancer Res 1994;54:4103-11.
26. Syvänen AC. Accessing genetic variation: genotyping single nucleotide polymorphisms. Nat Rev Genet 2001;2:930-42.
27. Coughtrie MW, Gilissen RA, Shek B, Strange RC, Fryer AA, Jones PW, Bamber DE. Phenol sulphotransferase SULT1A1 polymorphism: molecular diagnosis and allele frequencies in Caucasian and African populations. Biochem J 1999;337:45-9.
28. Arand M, Muhlbauer R, Hengstler J, Jager E, Fuchs J, Winkler L, Oesch F. A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathione S-transferase GSTM1 and GSTT1 polymorphisms. Anal Biochem 1996;236:184-6.
29. Kleinbaum DG, Kupper LL, Morgenstern H. Epidemiologic research. New York: Van Nostrand Reinhold, 1982.
30. Kleinbaum DG, Kupper LL, Muller KE. Applied regression analysis and other multivariable methods. Boston: PWS-KENT Publishing Company, 1998.
31. Khoury M. Genetic epidemiology. In: Rothman KJ, Greenland S, eds. Modern epidemiology. Philadelphia: Lippincott-Raven, Publishers, 1998. 609-21.
32. Botto LD, Khoury MJ. Commentary: facing the challenge of gene-environment interaction: the two-by-four table and beyond. Am J Epidemiol 2001;153:1016-20.
33. Russo J, Tay LK, Russo IH. Differentiation of the mammary gland and susceptibility to carcinogenesis. Breast Cancer Res Treat 1982;2:5-73.
34. Miller DP, Liu G, De Vivo I, Lynch TJ, Wain JC, Su L, Christiani DC. Combinations of the variant genotypes of GSTP1, GSTM1, and p53 are associated with an increased lung cancer risk. Cancer Res 2002;62:2819-23.
35. Ambrosone CB, Sweeney C, Coles BF, Thompson PA, McClure GY, Korourian S, Fares MY, Stone A, Kadlubar FF, Hutchins LF. Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer. Cancer Res 2001;61:7130-5.
36. Kim MJ, Cardiff RD, Desai N, Banach-Petrosky WA, Parsons R, Shen MM, Abate-Shen C. Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis. Proc Natl Acad Sci USA 2002;99:2884-9.
37. Russo J, Tahin Q, Lareef MH, Hu YF, Russo IH. Neoplastic transformation of human breast epithelial cells by estrogens and chemical carcinogens. Environ Mol Mutagen 2002;39:254-63.
38. Willett WC. Diet and breast cancer. J Intern Med, 2001;249:395-411.
39. Fearon ER. Human cancer syndromes: clues to the origin and nature of cancer. Science 1997;278:1043-50.
40. Bray NJ, Buckland PR, Williams NM, Williams HJ, Norton N, Owen MJ, O'Donovan MC. A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain. Am J Hum Genet 2003;73:152-61.
41. Bosma PJ. Inherited disorders of bilirubin metabolism. J Hepatol 2003;38:107-17.
42. Concannon P. ATM heterozygosity and cancer risk. Nat Genet 2002;32:89-90.
43. Nakachi K, Imai K, Hayashi S, Kawajiri K. Polymorphism of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population. Cancer Res 1993;53:2994-9.
44. Bernstein L, Yuan JM, Ross RK, Pike MC, Hanisch R, Lobo R, Stanczyk F, Gao YT, Henderson BE. Serum hormone levels in premenopausal Chinese women in Shanghai and white women in Los Angeles: results from two breast cancer case-control studies. Cancer Causes Control 1990;1:51-8.
45. Zhu BT, Conney AH. Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis 1998;19:1-27.
46. Zhu BT, Conney AH. Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis? Cancer Res 1998;58:2269-77.
47. Hayes JD, Pulford DJ. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 1995;30:445-600.
48. West SC. Molecular views of recombination proteins and their control. Nat Rev Mol Cell Biol 2003;4:435-45.
49. Pharoah PD, Antoniou A, Bobrow M, Zimmern RL, Easton DF, Ponder BA. Polygenic susceptibility to breast cancer and implications for prevention. Nat Genet 2002;3:33-6.