TGFβ1 (Leu10Pro), p53 (Arg72Pro) can predict for increased risk for breast cancer in south Indian women and TGFβ1 Pro (Leu10Pro) allele predicts response to neo-adjuvant chemo-radiotherapy

Breast Cancer Research and Treatment

Volumn 112, Issue 1, 2008, Pages 81-87

  Rajkumar, Thangarajan ^a   Samson, Mani ^a   Rama, Ranganathan ^a   Sridevi, Veluswami ^a   Mahji, Urmila ^a   Swaminathan, Rajaraman ^a   Nancy, Nirmala K ^a  

^a CANCER INSTITUTE WIA   (India)

Author keywords

Breast cancer; c erbB2 (Ile655Val); GSTM1 (Present Null); GSTP1 (Ile105Val); GSTT1 (Null Present); p53 (Arg72Pro); Response to neo adjuvant therapy; SNP; TGF 1 (Leu10Pro)

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUOROURACIL; METHOTREXATE; PROTEIN P53; TAMOXIFEN; TRANSFORMING GROWTH FACTOR BETA1; BETAIG H3 PROTEIN; BETAIG-H3 PROTEIN; DNA; GLUTATHIONE S-TRANSFERASE M1; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GSTP1 PROTEIN, HUMAN; SCLEROPROTEIN; TP53 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER INCIDENCE; CANCER RADIOTHERAPY; CANCER RISK; CONTROLLED STUDY; GENOTYPE; HUMAN; INDIAN; MAJOR CLINICAL STUDY; MASTECTOMY; MULTIPLE CYCLE TREATMENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; TREATMENT RESPONSE; ADJUVANT CHEMOTHERAPY; ADJUVANT THERAPY; BREAST TUMOR; CASE CONTROL STUDY; FEMALE; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; INDIA; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK; RISK FACTOR;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CHEMOTHERAPY, ADJUVANT; DNA, NEOPLASM; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; INDIA; MASTECTOMY; NEOADJUVANT THERAPY; ODDS RATIO; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; RADIOTHERAPY, ADJUVANT; RISK FACTORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 52949148184     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-007-9821-3     Document Type: Article

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