Analysis of molecular diversity of the Trypanosoma cruzi trypomastigote small surface antigen reveals novel epitopes, evidence of positive selection and potential implications for lineage-specific serology

International Journal for Parasitology

Volumn 40, Issue 8, 2010, Pages 921-928

  Bhattacharyya, Tapan ^a   Brooks, Jessica ^a   Yeo, Matthew ^a   Carrasco, Hernan J ^b   Lewis, Michael D ^a   Llewellyn, Martin S ^a   Miles, Michael A ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

Author keywords

Chagas disease; Molecular epidemiology; Phylogenetic; Serology; Trypanosoma cruzi; TSSA

Indexed keywords

EPITOPE; PARASITE ANTIGEN; TRYPOMASTIGOTE SMALL SURFACE ANTIGEN; UNCLASSIFIED DRUG;

ANTIGEN; CHAGAS DISEASE; EPIDEMIOLOGY; GENOTYPE; PARASITIC DISEASE; PARASITOLOGY; PHYLOGENETICS; POLYMERASE CHAIN REACTION; PROTOZOAN; SERUM;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGEN SPECIFICITY; ARTICLE; CELL LINEAGE; CHAGAS DISEASE; COMPARATIVE STUDY; CONTROLLED STUDY; GENE SEQUENCE; GENETIC HETEROGENEITY; GENETIC VARIABILITY; GENOTYPE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE IDENTIFICATION; PHYLOGENY; POLYMERASE CHAIN REACTION; SEROLOGY; SOUTH AND CENTRAL AMERICA; TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGENS, SURFACE; CHAGAS DISEASE; CLUSTER ANALYSIS; DNA, PROTOZOAN; EPITOPES; GENETIC VARIATION; GENOTYPE; HUMANS; LATIN AMERICA; MOLECULAR SEQUENCE DATA; PHYLOGENY; SELECTION, GENETIC; SEQUENCE ALIGNMENT; TRYPANOSOMA CRUZI;

LATIN AMERICA;

TRYPANOSOMA CRUZI;

EID: 77953027700     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2010.01.002     Document Type: Article

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