A new-generation 5-nitroimidazole can induce highly metronidazole-resistant Giardia lamblia in vitro

International Journal of Antimicrobial Agents

Volumn 36, Issue 1, 2010, Pages 37-42

  Dunn, Linda A ^a   Burgess, Anita G ^a   Krauer, Kenia G ^a   Eckmann, Lars ^b   Vanelle, Patrice ^c   Crozet, Maxime D ^c   Gillin, Frances D ^d   Upcroft, Peter ^a   Upcroft, Jacqueline A ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c AIX MARSEILLE UNIVERSITY   (France)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

5 Nitroimidazole; Cross resistance; Pyruvate:ferredoxin oxidoreductase; Ronidazole; Tinidazole

Indexed keywords

2 [1,2 DIBROMO 2 (4 METHYLPHENYL)ETHYL] 1 METHYL 5 NITRO 1H IMIDAZOLE; 5 NITROIMIDAZOLE DERIVATIVE; ANTIPROTOZOAL AGENT; COMPOUND 14; COMPOUND 18; FERREDOXIN; FURAZOLIDONE; METRONIDAZOLE; NITAZOXANIDE; ORNIDAZOLE; PYRUVATE SYNTHASE; RADICAL; RONIDAZOLE; TINIDAZOLE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SENSITIVITY; DRUG STRUCTURE; GIARDIA LAMBLIA; IN VITRO STUDY; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTIPROTOZOAL AGENTS; DRUG RESISTANCE; FREE RADICALS; GIARDIA LAMBLIA; METRONIDAZOLE; NITROIMIDAZOLES; PROTOZOAN PROTEINS; PYRUVATE SYNTHASE;

EID: 77953027255     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2010.03.004     Document Type: Article

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