TRAIL upregulates decoy receptor 1 and mediates resistance to apoptosis in insulin-secreting INS-1 cells

Biochemical and Biophysical Research Communications

Volumn 396, Issue 3, 2010, Pages 731-735

  Kang, Soojeong ^a   Park, So Young ^a   Lee, Hye Jeong ^a   Yoo, Young Hyun ^a  

^a Dong A University College of Medicine   (South Korea)

Author keywords

Decoy receptor; INS 1 cells; NF B; Resistance; TRAIL

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; DEATH RECEPTOR 4; DEATH RECEPTOR 5; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR 3;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVATION; GENE EXPRESSION; GENE FUNCTION; GENE TRANSLOCATION; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; REGULATORY MECHANISM; UPREGULATION;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; DIABETES MELLITUS, TYPE 1; HUMANS; I-KAPPA B PROTEINS; INSULIN; INSULIN-SECRETING CELLS; NF-KAPPA B; NITRILES; RATS; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 10C; SULFONES; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 77953020331     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.05.004     Document Type: Article

References (25)

1. Eizirik D.L., and Darville M.I. β-cell apoptosis and defense mechanisms: lessons from type 1 diabetes. Diabetes 50 Suppl. 1 (2001) S64-S69
2. Kagi D., Ho A., Odermatt B., Zakarian A., Ohashi P.S., and Mak T.W. TNF-receptor 1-dependent β cell toxicity as an effector pathway in autoimmune diabetes. J. Immunol. 162 (1999) 4598-4605
3. Loweth A.C., Williams G.T., James R.F., Scarpello J.H., and Morgan N.G. Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1β and Fas ligation. Diabetes 47 (1998) 727-732
4. Cnop M., Welsh N., Jonas J.C., Jorns A., Lenzen S., and Eizirik D.L. Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 54 Suppl. 2 (2005) S97-S107
5. Wachlin G., Augstein P., Schroder D., Kuttler B., Kloting I., Heinke P., and Schmidt S. IL-1β, IFN-gamma and TNF-alpha increase vulnerability of pancreatic β cells to autoimmune destruction. J. Autoimmun. 20 (2003) 303-312
6. Wiley S.R., Schooley K., Smolak P.J., Din W.S., Huang C.P., Nicholl J.K., Sutherland G.R., Smith T.D., Rauch C., Smith C.A., et al. Identification and characterization of a new member of the TNF-family that induces apoptosis. Immunity 3 (1995) 673-682
7. Griffith T.S., and Lynch D.H. TRAIL: a molecule with multiple receptors and control mechanisms. Curr. Opin. Immunol. 10 (1998) 559-563
8. Griffith T.S., Rauch C.T., Smolak P.J., Waugh J.Y., Boiani N., Lynch D.H., Smith C.A., Goodwin R.G., and Kubin M.Z. Functional analysis of TRAIL receptors using monoclonal antibodies. J. Immunol. 162 (1999) 2597-2605
9. Lamhamedi-Cherradi S.E., Zheng S., Tisch R.M., and Chen Y.H. Critical roles of tumor necrosis factor-related apoptosis-inducing ligand in type 1 diabetes. Diabetes 52 (2003) 2274-2278
10. Mi Q.S., Ly D., Lamhamedi-Cherradi S.E., Salojin K.V., Zhou L., Grattan M., Meagher C., Zucker P., Chen Y.H., Nagle J., Taub D., and Delovitch T.L. Blockade of tumor necrosis factor-related apoptosis-inducing ligand exacerbates type 1 diabetes in NOD mice. Diabetes 52 (2003) 1967-1975
11. Ou D., Metzger D.L., Wang X., Huang J., Pozzilli P., and Tingle A.J. TNF-related apoptosis-inducing ligand death pathway-mediated human β-cell destruction. Diabetologia 45 (2002) 1678-1688
12. Ou D., Wang X., Metzger D.L., Robbins M., Huang J., Jobin C., Chantler J.K., James R.F., Pozzilli P., and Tingle A.J. Regulation of TNF-related apoptosis-inducing ligand-mediated death-signal pathway in human β cells by Fas-associated death domain and nuclear factor kappaB. Hum. Immunol. 66 (2005) 799-809
13. Asfari M., Janjic D., Meda P., Li G., Halban P.A., and Wollheim C.B. Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 130 (1992) 167-178
14. Pierce J.W., Schoenleber R., Jesmok G., Best J., Moore S.A., Collins T., and Gerritsen M.E. Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-iNF-lammatory effects in vivo. J. Biol. Chem. 272 (1997) 21096-21103
15. Bernard D., Quatannens B., Vandenbunder B., and Abbadie C. Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF-)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1. J. Biol. Chem. 276 (2001) 27322-27328
16. Cretney E., Takeda K., Yagita H., Glaccum M., Peschon J.J., and Smyth M.J. Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J. Immunol. 168 (2002) 1356-1361
17. Song K., Chen Y., Goke R., Wilmen A., Seidel C., Goke A., Hilliard B., and Chen Y. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune iNF-lammation and cell cycle progression. J. Exp. Med. 191 (2000) 1095-1104
18. Hilliard B., Wilmen A., Seidel C., Liu T.S., Goke R., and Chen Y. Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis. J. Immunol. 166 (2001) 1314-1319
19. Ashkenazi A., and Dixit V.M. Apoptosis control by death and decoy receptors. Curr. Opin. Cell Biol. 11 (1999) 255-260
20. Lunemann J.D., Waiczies S., Ehrlich S., Wendling U., Seeger B., Kamradt T., and Zipp F. Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells. J. Immunol. 168 (2002) 4881-4888
21. Satoh K., Kaneko K., Hirota M., Masamune A., Satoh A., and Shimosegawa T. Tumor necrosis factor-related apoptosis-inducing ligand and its receptor expression and the pathway of apoptosis in human pancreatic cancer. Pancreas 23 (2001) 251-258
22. Goke R., Goke A., Goke B., and Chen Y. Regulation of TRAIL-induced apoptosis by transcription factors. Cell. Immunol. 201 (2000) 77-82
23. Wu G.S., Burns T.F., McDonald III E.R., Meng R.D., Kao G., Muschel R., Yen T., and el-Deiry W.S. Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest. Oncogene 18 (1999) 6411-6418
24. Takimoto R., and El-Deiry W.S. Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site. Oncogene 19 (2000) 1735-1743
25. Zhang X.D., Nguyen T., Thomas W.D., Sanders J.E., and Hersey P. Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types. FEBS Lett. 482 (2000) 193-199