Implication of necrosis-linked p53 aggregation in acquired apoptotic resistance to 5-FU in MCF-7 multicellular tumour spheroids

Oncology Reports

Volumn 24, Issue 1, 2010, Pages 73-79

  Lee, Su Yeon ^a   Jeong, Eui Kyong ^a   Jeon, Hyun Min ^a   Kim, Cho Hee ^a   Kang, Ho Sung ^a  

^a Pusan National University   (South Korea)

Author keywords

5 Fluorouracil; Acquired apoptotic resistance; Multicellular tumour spheroids; Necrosis; P53 aggregation

Indexed keywords

AGAROSE; FLUOROURACIL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL DEATH; CELL STRAIN MCF 7; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CLEAVAGE; PROTEIN INDUCTION; TUMOR CELL CULTURE; TUMOR SPHEROID; ADENOCARCINOMA; BIOLOGICAL MODEL; BREAST NEOPLASMS; DRUG EFFECTS; DRUG RESISTANCE; FEMALE; METABOLISM; MULTICELLULAR SPHEROID; NECROSIS; PATHOLOGY; PHYSIOLOGY; PRECIPITATION; PROTEIN MULTIMERIZATION; TUMOR CELL LINE;

ADENOCARCINOMA; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CHEMICAL PRECIPITATION; DRUG RESISTANCE, NEOPLASM; FEMALE; FLUOROURACIL; HUMANS; MODELS, BIOLOGICAL; NECROSIS; PROTEIN MULTIMERIZATION; SPHEROIDS, CELLULAR; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77952983073     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000830     Document Type: Article

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