메뉴 건너뛰기




Volumn 108, Issue 1, 2009, Pages 169-180

NF-kappa B is required for the development of tumor spheroids

Author keywords

Cancer; Drug resistance; NF kappa B; Three dimensional cell culture; Transduction pathways; X linked inhibitor of apoptosis proteins

Indexed keywords

CISPLATIN; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PACLITAXEL; SMALL INTERFERING RNA; STAUROSPORINE; TAMOXIFEN; X LINKED INHIBITOR OF APOPTOSIS;

EID: 69249120868     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22237     Document Type: Article
Times cited : (25)

References (51)
  • 3
    • 0035400540 scopus 로고    scopus 로고
    • Inhibitor of apoptosis-1 (IAP-1) expression and apoptosis in non-small-cell lung cancer cells exposed to gemcitabine
    • Bandala E, Espinosa M, Maldonado V, Melendez-Zajgla J. 2001. Inhibitor of apoptosis-1 (IAP-1) expression and apoptosis in non-small-cell lung cancer cells exposed to gemcitabine. Biochem Pharmacol 62:13-19.
    • (2001) Biochem Pharmacol , vol.62 , pp. 13-19
    • Bandala, E.1    Espinosa, M.2    Maldonado, V.3    Melendez-Zajgla, J.4
  • 4
    • 45149094559 scopus 로고    scopus 로고
    • Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids
    • Barbone D, Yang TM, Morgan JR, Gaudino G, Broaddus VC. 2008. Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids. J Biol Chem 283:13021-13030.
    • (2008) J Biol Chem , vol.283 , pp. 13021-13030
    • Barbone, D.1    Yang, T.M.2    Morgan, J.R.3    Gaudino, G.4    Broaddus, V.C.5
  • 6
    • 0017414436 scopus 로고
    • A computer simulation of the growth of a tumour in vitro
    • Burkowski FJ. 1977. A computer simulation of the growth of a tumour in vitro. Comput Programs Biomed 7:203-210.
    • (1977) Comput Programs Biomed , vol.7 , pp. 203-210
    • Burkowski, F.J.1
  • 10
    • 0016822219 scopus 로고
    • Model for the growth of a solid in vitro tumor
    • Deakin AS. 1975. Model for the growth of a solid in vitro tumor. Growth 39:159-165.
    • (1975) Growth , vol.39 , pp. 159-165
    • Deakin, A.S.1
  • 11
    • 0019425678 scopus 로고
    • Increased radioresistance of cells in cultured multicell spheroids. I. Dependence on cellular interaction
    • Dertinger H, Hulser D. 1981. Increased radioresistance of cells in cultured multicell spheroids. I. Dependence on cellular interaction. Radiat Environ Biophys 19:101-107.
    • (1981) Radiat Environ Biophys , vol.19 , pp. 101-107
    • Dertinger, H.1    Hulser, D.2
  • 12
    • 1542782936 scopus 로고    scopus 로고
    • Therapeutic potential of retroviral RNAi vectors
    • Devroe E, Silver PA. 2004. Therapeutic potential of retroviral RNAi vectors. Expert Opin Biol Ther 4:319-327.
    • (2004) Expert Opin Biol Ther , vol.4 , pp. 319-327
    • Devroe, E.1    Silver, P.A.2
  • 14
    • 0033817518 scopus 로고    scopus 로고
    • Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341
    • Frankel A, Man S, Elliott P, Adams J, Kerbel RS. 2000. Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341. Clin Cancer Res 6:3719-3728.
    • (2000) Clin Cancer Res , vol.6 , pp. 3719-3728
    • Frankel, A.1    Man, S.2    Elliott, P.3    Adams, J.4    Kerbel, R.S.5
  • 15
    • 0031837969 scopus 로고    scopus 로고
    • Decreased mitochondrial function in quiescent cells isolated from multicellular tumor spheroids
    • Freyer JP. 1998. Decreased mitochondrial function in quiescent cells isolated from multicellular tumor spheroids. J Cell Physiol 176:138-149.
    • (1998) J Cell Physiol , vol.176 , pp. 138-149
    • Freyer, J.P.1
  • 16
    • 0029870493 scopus 로고    scopus 로고
    • The non-variation in radiosensitivity of different proliferative states of human glioma cells
    • Gronvik C, Capala J, Carlsson J. 1996. The non-variation in radiosensitivity of different proliferative states of human glioma cells. Anticancer Res 16:25-31.
    • (1996) Anticancer Res , vol.16 , pp. 25-31
    • Gronvik, C.1    Capala, J.2    Carlsson, J.3
  • 17
    • 33847046746 scopus 로고    scopus 로고
    • Activated stress response pathways within multicellular aggregates utilize an autocrine component
    • Jack GD, Cabrera MC, Manning ML, Slaughter SM, Potts M, Helm RF. 2007. Activated stress response pathways within multicellular aggregates utilize an autocrine component. Cell Signal 19:772-781.
    • (2007) Cell Signal , vol.19 , pp. 772-781
    • Jack, G.D.1    Cabrera, M.C.2    Manning, M.L.3    Slaughter, S.M.4    Potts, M.5    Helm, R.F.6
  • 19
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin M. 2006. Nuclear factor-kappaB in cancer development and progression. Nature 441:431-436.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 20
    • 33645378251 scopus 로고    scopus 로고
    • Establishment and characterization of multicellular spheroids from a human glioma cell line; Implications for tumor therapy
    • Khaitan D, Chandna S, Arya MB, Dwarakanath BS. 2006. Establishment and characterization of multicellular spheroids from a human glioma cell line; Implications for tumor therapy. J Transl Med 4:12.
    • (2006) J Transl Med , vol.4 , pp. 12
    • Khaitan, D.1    Chandna, S.2    Arya, M.B.3    Dwarakanath, B.S.4
  • 21
    • 0030815278 scopus 로고    scopus 로고
    • Drug resistance conferred by MDR1 expression in spheroids formed by glioblastoma cell lines
    • Kolchinsky A, Roninson IB. 1997. Drug resistance conferred by MDR1 expression in spheroids formed by glioblastoma cell lines. Anticancer Res 17:3321-3327.
    • (1997) Anticancer Res , vol.17 , pp. 3321-3327
    • Kolchinsky, A.1    Roninson, I.B.2
  • 22
    • 0033101647 scopus 로고    scopus 로고
    • Multicellular tumor spheroids: Intermediates between monolayer culture and in vivo tumor
    • Kunz-Schughart LA. 1999. Multicellular tumor spheroids: Intermediates between monolayer culture and in vivo tumor. Cell Biol Int 23:157-161.
    • (1999) Cell Biol Int , vol.23 , pp. 157-161
    • Kunz-Schughart, L.A.1
  • 23
    • 0018898633 scopus 로고
    • The multicellular tumor spheroid model. II. Characterization of the primary allograft response in unsensitized mice
    • Lord EM, Nardella G. 1980. The multicellular tumor spheroid model. II. Characterization of the primary allograft response in unsensitized mice. Transplantation 29:119-124.
    • (1980) Transplantation , vol.29 , pp. 119-124
    • Lord, E.M.1    Nardella, G.2
  • 24
    • 0018232318 scopus 로고
    • The multicellular spheroid as a model tumor allograft. I. Quantitative assessment of spheroid destruction in alloimmune mice
    • MacDonald HR, Howell RL. 1978. The multicellular spheroid as a model tumor allograft. I. Quantitative assessment of spheroid destruction in alloimmune mice. Transplantation 25:136-140.
    • (1978) Transplantation , vol.25 , pp. 136-140
    • MacDonald, H.R.1    Howell, R.L.2
  • 25
    • 0018236964 scopus 로고
    • The multicellular spheroid as a model tumor allograft. II. Characterization of spheroid-infiltrating cytotoxic cells
    • MacDonald HR, Howell RL, McFarlane DL. 1978. The multicellular spheroid as a model tumor allograft. II. Characterization of spheroid-infiltrating cytotoxic cells. Transplantation 25:141-145.
    • (1978) Transplantation , vol.25 , pp. 141-145
    • MacDonald, H.R.1    Howell, R.L.2    McFarlane, D.L.3
  • 27
    • 0023093713 scopus 로고
    • Multicellular spheroids. A review on cellular aggregates in cancer research
    • Mueller-Klieser W. 1987. Multicellular spheroids. A review on cellular aggregates in cancer research. J Cancer Res Clin Oncol 113:101-122.
    • (1987) J Cancer Res Clin Oncol , vol.113 , pp. 101-122
    • Mueller-Klieser, W.1
  • 28
    • 0030697292 scopus 로고    scopus 로고
    • Three-dimensional cell cultures: From molecular mechanisms to clinical applications
    • Mueller-Klieser W. 1997. Three-dimensional cell cultures: From molecular mechanisms to clinical applications. Am J Physiol 273:C1109-C1123.
    • (1997) Am J Physiol , vol.273
    • Mueller-Klieser, W.1
  • 29
    • 3042660431 scopus 로고    scopus 로고
    • The inhibitor of apoptosis protein family (IAPs): An emerging therapeutic target in cancer
    • Nachmias B, Ashhab Y, Ben-Yehuda D. 2004. The inhibitor of apoptosis protein family (IAPs): An emerging therapeutic target in cancer. Semin Cancer Biol 14:231-243.
    • (2004) Semin Cancer Biol , vol.14 , pp. 231-243
    • Nachmias, B.1    Ashhab, Y.2    Ben-Yehuda, D.3
  • 30
    • 0022447088 scopus 로고
    • Density distributions of human squamous carcinoma cells: Influence of growth conditions, proliferative status and DNA content
    • Ng CE, Keng PC, Sutherland RM. 1986. Density distributions of human squamous carcinoma cells: Influence of growth conditions, proliferative status and DNA content. Int J Cancer 38:413-418.
    • (1986) Int J Cancer , vol.38 , pp. 413-418
    • Ng, C.E.1    Keng, P.C.2    Sutherland, R.M.3
  • 32
    • 33947605546 scopus 로고    scopus 로고
    • NF-kappa B signaling and carcinogenesis
    • Okamoto T, Sanda T, Asamitsu K. 2007. NF-kappa B signaling and carcinogenesis. Curr Pharm Des 13:447-462.
    • (2007) Curr Pharm Des , vol.13 , pp. 447-462
    • Okamoto, T.1    Sanda, T.2    Asamitsu, K.3
  • 33
    • 0028361447 scopus 로고
    • Drug and radiation resistance in spheroids: Cell contact and kinetics
    • Olive PL, Durand RE. 1994. Drug and radiation resistance in spheroids: Cell contact and kinetics. Cancer Metastasis Rev 13:121-138.
    • (1994) Cancer Metastasis Rev , vol.13 , pp. 121-138
    • Olive, P.L.1    Durand, R.E.2
  • 34
    • 0034667463 scopus 로고    scopus 로고
    • Changes in subcellular distribution of topoisomerase IIalpha correlate with etoposide resistance in multicell spheroids and xenograft tumors
    • Oloumi A, MacPhail SH, Johnston PJ, Banath JP, Olive PL. 2000. Changes in subcellular distribution of topoisomerase IIalpha correlate with etoposide resistance in multicell spheroids and xenograft tumors. Cancer Res 60:5747-5753.
    • (2000) Cancer Res , vol.60 , pp. 5747-5753
    • Oloumi, A.1    MacPhail, S.H.2    Johnston, P.J.3    Banath, J.P.4    Olive, P.L.5
  • 35
    • 16644394363 scopus 로고    scopus 로고
    • Caspases: Potential targets for regulating cell death
    • Philchenkov A. 2004. Caspases: Potential targets for regulating cell death. J Cell Mol Med 8:432-444.
    • (2004) J Cell Mol Med , vol.8 , pp. 432-444
    • Philchenkov, A.1
  • 36
    • 33646705888 scopus 로고    scopus 로고
    • NF-kappaB: A stress-regulated switch for cell survival
    • Piva R, Belardo G, Santoro MG. 2006. NF-kappaB: A stress-regulated switch for cell survival. Antioxid Redox Signal 8:478-486.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 478-486
    • Piva, R.1    Belardo, G.2    Santoro, M.G.3
  • 39
    • 0031594495 scopus 로고    scopus 로고
    • Hypotonic Ca2+ signaling and volume regulation in proliferating and quiescent cells from multicellular spheroids
    • Sauer H, Ritgen J, Hescheler J, Wartenberg M. 1998. Hypotonic Ca2+ signaling and volume regulation in proliferating and quiescent cells from multicellular spheroids. J Cell Physiol 175:129-140.
    • (1998) J Cell Physiol , vol.175 , pp. 129-140
    • Sauer, H.1    Ritgen, J.2    Hescheler, J.3    Wartenberg, M.4
  • 40
    • 0028870050 scopus 로고
    • Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
    • Shweiki D, Neeman M, Itin A, Keshet E. 1995. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis. Proc Natl Acad Sci USA 92:768-772.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 768-772
    • Shweiki, D.1    Neeman, M.2    Itin, A.3    Keshet, E.4
  • 42
    • 0032490670 scopus 로고    scopus 로고
    • Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis
    • Stehlik C, de Martin R, Kumabashiri I, Schmid JA, Binder BR, Lipp J. 1998. Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis. J Exp Med 188:211-216.
    • (1998) J Exp Med , vol.188 , pp. 211-216
    • Stehlik, C.1    de Martin, R.2    Kumabashiri, I.3    Schmid, J.A.4    Binder, B.R.5    Lipp, J.6
  • 43
    • 38949105541 scopus 로고    scopus 로고
    • Independent activation of Akt and NF-kappaB pathways and their role in resistance to TNF-alpha mediated cytotoxicity in gliomas
    • Sudheerkumar P, Shiras A, Das G, Jagtap JC, Prasad V, Shastry P. 2008. Independent activation of Akt and NF-kappaB pathways and their role in resistance to TNF-alpha mediated cytotoxicity in gliomas. Mol Carcinog 47:126-136.
    • (2008) Mol Carcinog , vol.47 , pp. 126-136
    • Sudheerkumar, P.1    Shiras, A.2    Das, G.3    Jagtap, J.C.4    Prasad, V.5    Shastry, P.6
  • 44
    • 0024281372 scopus 로고
    • Cell and environment interactions in tumor microregions: The multicell spheroid model
    • Sutherland RM. 1988. Cell and environment interactions in tumor microregions: The multicell spheroid model. Science 240:177-184.
    • (1988) Science , vol.240 , pp. 177-184
    • Sutherland, R.M.1
  • 45
    • 0029953942 scopus 로고    scopus 로고
    • Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors
    • Uren AG, Pakusch M, Hawkins CJ, Puls KL, Vaux DL. 1996. Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Proc Natl Acad Sci USA 93:4974-4978.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4974-4978
    • Uren, A.G.1    Pakusch, M.2    Hawkins, C.J.3    Puls, K.L.4    Vaux, D.L.5
  • 46
    • 1242338943 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein function by XR9576 in a solid tumour model can restore anticancer drug efficacy
    • Walker J, Martin C, Callaghan R. 2004. Inhibition of P-glycoprotein function by XR9576 in a solid tumour model can restore anticancer drug efficacy. Eur J Cancer 40:594-605.
    • (2004) Eur J Cancer , vol.40 , pp. 594-605
    • Walker, J.1    Martin, C.2    Callaghan, R.3
  • 47
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS, Jr. 1998. NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281:1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin Jr., A.S.5
  • 48
    • 37249079575 scopus 로고    scopus 로고
    • Knock-down of P-glycoprotein reverses taxol resistance in ovarian cancer multicellular spheroids
    • Xing H, Wang S, Weng D, Chen G, Yang X, Zhou J, Xu G, Lu Y, Ma D. 2007. Knock-down of P-glycoprotein reverses taxol resistance in ovarian cancer multicellular spheroids. Oncol Rep 17:117-122.
    • (2007) Oncol Rep , vol.17 , pp. 117-122
    • Xing, H.1    Wang, S.2    Weng, D.3    Chen, G.4    Yang, X.5    Zhou, J.6    Xu, G.7    Lu, Y.8    Ma, D.9
  • 50
    • 0017726744 scopus 로고
    • A simplified method for production and growth of multicellular tumor spheroids
    • Yuhas JM, Li AP, Martinez AO, Ladman AJ. 1977. A simplified method for production and growth of multicellular tumor spheroids. Cancer Res 37:3639-3643.
    • (1977) Cancer Res , vol.37 , pp. 3639-3643
    • Yuhas, J.M.1    Li, A.P.2    Martinez, A.O.3    Ladman, A.J.4
  • 51
    • 33749572210 scopus 로고    scopus 로고
    • Carcinogenesis and apoptosis: Paradigms and paradoxes
    • Zhivotovsky B, Orrenius S. 2006. Carcinogenesis and apoptosis: Paradigms and paradoxes. Carcinogenesis 27:1939-1945.
    • (2006) Carcinogenesis , vol.27 , pp. 1939-1945
    • Zhivotovsky, B.1    Orrenius, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.