메뉴 건너뛰기




Volumn 33, Issue 4, 2010, Pages 323-329

Endogenous cannabinoids in liver disease: Many darts for a single target;Cannabinoides endógenos en la enfermedad hepática: muchos dardos para una sola diana

Author keywords

Anandamide; Endocannabinoids; Liver cirrhosis

Indexed keywords

ENDOCANNABINOID;

EID: 77952884999     PISSN: 02105705     EISSN: 15789519     Source Type: Journal    
DOI: 10.1016/j.gastrohep.2009.06.010     Document Type: Article
Times cited : (7)

References (48)
  • 1
    • 0003031819 scopus 로고    scopus 로고
    • Renal dysfunction in cirrhosis
    • Oxford Medical Publications, Oxford, UK, J. Bircher, J.P. Benhamou, N. McIntire, M. Rizzetto, J. Rodés (Eds.)
    • Arroyo V., Ginès P., Jiménez W., Rodés J. Renal dysfunction in cirrhosis. Oxford textbook of clinical hepatology 1999, 733-761. Oxford Medical Publications, Oxford, UK. 2 ed. J. Bircher, J.P. Benhamou, N. McIntire, M. Rizzetto, J. Rodés (Eds.).
    • (1999) Oxford textbook of clinical hepatology , pp. 733-761
    • Arroyo, V.1    Ginès, P.2    Jiménez, W.3    Rodés, J.4
  • 2
    • 48249136051 scopus 로고    scopus 로고
    • Emerging role of cannabinoids in gastrointestinal and liver diseases: Basic and clinical aspects
    • Izzo A.A., Camilleri M. Emerging role of cannabinoids in gastrointestinal and liver diseases: Basic and clinical aspects. Gut 2008, 57:1140-1155.
    • (2008) Gut , vol.57 , pp. 1140-1155
    • Izzo, A.A.1    Camilleri, M.2
  • 3
    • 33748703859 scopus 로고    scopus 로고
    • The endocannabinoid system as an emerging target of pharmacotherapy
    • Pacher P., Bátkai S., Kunos G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev 2006, 58:389-462.
    • (2006) Pharmacol Rev , vol.58 , pp. 389-462
    • Pacher, P.1    Bátkai, S.2    Kunos, G.3
  • 4
    • 17844367093 scopus 로고    scopus 로고
    • Endocannabinoid and liver disease
    • Jiménez W. Endocannabinoid and liver disease. Hepatology 2005, 41:983-985.
    • (2005) Hepatology , vol.41 , pp. 983-985
    • Jiménez, W.1
  • 6
    • 45849112141 scopus 로고    scopus 로고
    • Endocannabinoids and liver disease. IV. Endocannabinoid involvement in obesity and hepatic steatosis
    • Kunos G., Osei-Hyiaman D. Endocannabinoids and liver disease. IV. Endocannabinoid involvement in obesity and hepatic steatosis. Am J Physiol 2008, 294:G1101-G1114.
    • (2008) Am J Physiol , vol.294
    • Kunos, G.1    Osei-Hyiaman, D.2
  • 7
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda L.A., Lolait S.J., Brownstein M.J., Young A.C., Bonner T.I. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 1990, 346:561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 8
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S., Thomas K.L., Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 1993, 365:61-65.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 9
    • 0027078685 scopus 로고
    • Isolation and structure of a brain constituent that binds to the cannabinoid receptor
    • Devane W.A., Hanus L., Breuer A., Pertwee R.G., Stevenson L.A., Griffin G., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 1992, 258:1946-1949.
    • (1992) Science , vol.258 , pp. 1946-1949
    • Devane, W.A.1    Hanus, L.2    Breuer, A.3    Pertwee, R.G.4    Stevenson, L.A.5    Griffin, G.6
  • 14
    • 0031823187 scopus 로고    scopus 로고
    • Platelet- and macrophage derived endogenous cannabinoids are involved in endotoxic-induced hypotension
    • Varga K., Wagner J.A., Bridgen D.T., Kunos G. Platelet- and macrophage derived endogenous cannabinoids are involved in endotoxic-induced hypotension. FASEB J 1998, 12:1035-1044.
    • (1998) FASEB J , vol.12 , pp. 1035-1044
    • Varga, K.1    Wagner, J.A.2    Bridgen, D.T.3    Kunos, G.4
  • 15
    • 0034928628 scopus 로고    scopus 로고
    • Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis
    • Bátkai S., Jarai Z., Wagner J.A., Goparaju S.K., Varga K., Liu J., et al. Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. Nat Med 2001, 7:827-832.
    • (2001) Nat Med , vol.7 , pp. 827-832
    • Bátkai, S.1    Jarai, Z.2    Wagner, J.A.3    Goparaju, S.K.4    Varga, K.5    Liu, J.6
  • 16
    • 0036142225 scopus 로고    scopus 로고
    • Endogenous cannabinoids: A new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat
    • Ros J., Clària J., To-Figueras J., Planagumà A., Cejudo-Martín P., Fernández-Varo G., et al. Endogenous cannabinoids: A new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat. Gastroenterology 2002, 122:85-93.
    • (2002) Gastroenterology , vol.122 , pp. 85-93
    • Ros, J.1    Clària, J.2    To-Figueras, J.3    Planagumà, A.4    Cejudo-Martín, P.5    Fernández-Varo, G.6
  • 17
    • 0142244903 scopus 로고    scopus 로고
    • Membrane cholesterol but not putative receptors mediate anandamide-induced hepatocyte apoptosis
    • Biswas K.K., Sarker K.P., Abeyama K., Kawahara K., Iino S., Otsubo Y., et al. Membrane cholesterol but not putative receptors mediate anandamide-induced hepatocyte apoptosis. Hepatology 2003, 38:1167-1177.
    • (2003) Hepatology , vol.38 , pp. 1167-1177
    • Biswas, K.K.1    Sarker, K.P.2    Abeyama, K.3    Kawahara, K.4    Iino, S.5    Otsubo, Y.6
  • 19
    • 20144379143 scopus 로고    scopus 로고
    • Increased anandamide induced relaxation in mesenteric arteries of cirrhotic rats: Role of cannabinoid and vanilloid receptors
    • Domenicali M., Ros J., Fernández-Varo G., Cejudo-Martín P., Crespo M., Morales-Ruiz M., et al. Increased anandamide induced relaxation in mesenteric arteries of cirrhotic rats: Role of cannabinoid and vanilloid receptors. Gut 2005, 54:522-527.
    • (2005) Gut , vol.54 , pp. 522-527
    • Domenicali, M.1    Ros, J.2    Fernández-Varo, G.3    Cejudo-Martín, P.4    Crespo, M.5    Morales-Ruiz, M.6
  • 20
    • 33845186019 scopus 로고    scopus 로고
    • Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB (1) and VR (1) receptors
    • Moezi L., Gaskari S.A., Liu H., Baik S.K., Dehpour A.R., Lee S.S. Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB (1) and VR (1) receptors. Br J Pharmacol 2006, 149:898-908.
    • (2006) Br J Pharmacol , vol.149 , pp. 898-908
    • Moezi, L.1    Gaskari, S.A.2    Liu, H.3    Baik, S.K.4    Dehpour, A.R.5    Lee, S.S.6
  • 21
    • 67449166655 scopus 로고    scopus 로고
    • Cannabinoid type 1 receptor antagonism delays ascites formation in rats with cirrhosis. Gastroenterology.;137:
    • Domenicali M, Caraceni P, Giannone F, Pertosa AM, Principe A, Zambruni A, et al. Cannabinoid type 1 receptor antagonism delays ascites formation in rats with cirrhosis. Gastroenterology. 2009;137:341-9.
    • (2009) , pp. 341-9
    • Domenicali, M.1    Caraceni, P.2    Giannone, F.3    Pertosa, A.M.4    Principe, A.5    Zambruni, A.6    et al7
  • 22
    • 0033755748 scopus 로고    scopus 로고
    • Is there a cirrhotic cardiomyopathy?
    • Blendis L., Wong F. Is there a cirrhotic cardiomyopathy?. Am J Gastroenterology 2000, 11:3026-3028.
    • (2000) Am J Gastroenterology , vol.11 , pp. 3026-3028
    • Blendis, L.1    Wong, F.2
  • 24
    • 0029145769 scopus 로고
    • Decreased right heart blood volume determined by magnetic resonance imaging: Evidence of central underfilling in cirrhosis
    • Moller S., Sondergaard L., Mogelvang J., Henriksen O, Henriksen J.H. Decreased right heart blood volume determined by magnetic resonance imaging: Evidence of central underfilling in cirrhosis. Hepatology 1995, 22:472-478.
    • (1995) Hepatology , vol.22 , pp. 472-478
    • Moller, S.1    Sondergaard, L.2    Mogelvang, J.3    Henriksen, O.4    Henriksen, J.H.5
  • 25
    • 0021210773 scopus 로고
    • Cardiac performance in patients with asymptomatic alcoholic cirrhosis of the liver
    • Kelbaek H., Eriksen J., Brynjolf I., Raboel A., Lund J.O., Munck O. Cardiac performance in patients with asymptomatic alcoholic cirrhosis of the liver. Am J Cardiol 1984, 54:852-855.
    • (1984) Am J Cardiol , vol.54 , pp. 852-855
    • Kelbaek, H.1    Eriksen, J.2    Brynjolf, I.3    Raboel, A.4    Lund, J.O.5    Munck, O.6
  • 26
    • 0029778989 scopus 로고    scopus 로고
    • Cirrhotic cardiomyopathy: Getting to the heart of the matter
    • Ma Z., Lee S.S. Cirrhotic cardiomyopathy: Getting to the heart of the matter. Hepatology 1996, 24:451-459.
    • (1996) Hepatology , vol.24 , pp. 451-459
    • Ma, Z.1    Lee, S.S.2
  • 27
    • 12644271202 scopus 로고    scopus 로고
    • Evidence of functional and structural cardiac abnormalities in cirrhotic patients with and without ascites
    • Pozzi M., Carugo S., Boari G., Pecci V., De Ceglia S., Maggolini S. Evidence of functional and structural cardiac abnormalities in cirrhotic patients with and without ascites. Hepatology 1997, 26:1131-1137.
    • (1997) Hepatology , vol.26 , pp. 1131-1137
    • Pozzi, M.1    Carugo, S.2    Boari, G.3    Pecci, V.4    De Ceglia, S.5    Maggolini, S.6
  • 28
    • 27144472559 scopus 로고    scopus 로고
    • Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats
    • Gaskari S.A., Liu H., Moezi L., Li Y., Baik S.K., Lee S.L. Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats. Br J Pharmacol 2005, 146:315-323.
    • (2005) Br J Pharmacol , vol.146 , pp. 315-323
    • Gaskari, S.A.1    Liu, H.2    Moezi, L.3    Li, Y.4    Baik, S.K.5    Lee, S.L.6
  • 29
    • 77952885773 scopus 로고    scopus 로고
    • Endogenous cannabinoids and cardiac dysfunction in cirrhosis
    • Ippolito S., Mani A.R., Moore K.P. Endogenous cannabinoids and cardiac dysfunction in cirrhosis. J Hepatol 2006, 44:S77.
    • (2006) J Hepatol , vol.44
    • Ippolito, S.1    Mani, A.R.2    Moore, K.P.3
  • 30
    • 34548444632 scopus 로고    scopus 로고
    • Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats
    • Bátkai S., Mukhopadhyay P., Harvey-White J., Kechrid R., Pacher P., Kunos G. Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. Am J Physiol 2007, 293:H1689-H1695.
    • (2007) Am J Physiol , vol.293
    • Bátkai, S.1    Mukhopadhyay, P.2    Harvey-White, J.3    Kechrid, R.4    Pacher, P.5    Kunos, G.6
  • 31
    • 21344472982 scopus 로고    scopus 로고
    • Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C
    • Hézode C., Roudot-Thoraval F., Nguyen S., Grenard P., Julien B., Zafrani E.S., et al. Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C. Hepatology 2005, 42:63-71.
    • (2005) Hepatology , vol.42 , pp. 63-71
    • Hézode, C.1    Roudot-Thoraval, F.2    Nguyen, S.3    Grenard, P.4    Julien, B.5    Zafrani, E.S.6
  • 33
    • 33745003240 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor antagonism: A new strategy for the treatment of liver fibrosis
    • Teixera-Clerc F., Julien B., Grenard P., Van Nhieu J.T., Deveaux V., Li L., et al. CB1 cannabinoid receptor antagonism: A new strategy for the treatment of liver fibrosis. Nat Med 2006, 12:671-676.
    • (2006) Nat Med , vol.12 , pp. 671-676
    • Teixera-Clerc, F.1    Julien, B.2    Grenard, P.3    Van Nhieu, J.T.4    Deveaux, V.5    Li, L.6
  • 35
    • 26844504226 scopus 로고    scopus 로고
    • Identification and functional characterization of brainstem cannabinoid CB2 receptors
    • Van Sickle M.D., Duncan M., Kingsley P.J., Mouihate A., Urbani P., Mackie K., et al. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science 2005, 310:329-332.
    • (2005) Science , vol.310 , pp. 329-332
    • Van Sickle, M.D.1    Duncan, M.2    Kingsley, P.J.3    Mouihate, A.4    Urbani, P.5    Mackie, K.6
  • 36
    • 27844463517 scopus 로고    scopus 로고
    • Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
    • Rimonabant in Obesity-Lipids Study Group
    • Després J.P., Golay A., Sjöström L. Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N Engl J Med 2005, 353:2121-2134. Rimonabant in Obesity-Lipids Study Group.
    • (2005) N Engl J Med , vol.353 , pp. 2121-2134
    • Després, J.P.1    Golay, A.2    Sjöström, L.3
  • 38
    • 34249788152 scopus 로고    scopus 로고
    • Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury
    • Bátkai S., Osei-Hyiaman D., Pan H., El-Assal, Rajesh M., Mukhopadhyay P., et al. Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury. FASEB J 2007, 21:1788-1800.
    • (2007) FASEB J , vol.21 , pp. 1788-1800
    • Bátkai, S.1    Osei-Hyiaman, D.2    Pan, H.3    El-Assal4    Rajesh, M.5    Mukhopadhyay, P.6
  • 39
    • 37249091964 scopus 로고    scopus 로고
    • Pivotal advance: Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response and apoptosis
    • Rajesh M., Pan H., Mukhopadhyay P., Bátkai S., Osei-Hyiaman, Haskó G., et al. Pivotal advance: Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response and apoptosis. J Leukoc Biol 2007, 82:1382-1389.
    • (2007) J Leukoc Biol , vol.82 , pp. 1382-1389
    • Rajesh, M.1    Pan, H.2    Mukhopadhyay, P.3    Bátkai, S.4    Osei-Hyiaman5    Haskó, G.6
  • 40
    • 29144480571 scopus 로고    scopus 로고
    • Endocannabinoids affect neurological and cognitive function in thioacetamide-induced hepatic encephalopathy in mice
    • Avraham Y., Israeli E., Gabbay E., Okun A., Zolotarev O., Silberman I., et al. Endocannabinoids affect neurological and cognitive function in thioacetamide-induced hepatic encephalopathy in mice. Neurobiol Dis 2006, 21:237-245.
    • (2006) Neurobiol Dis , vol.21 , pp. 237-245
    • Avraham, Y.1    Israeli, E.2    Gabbay, E.3    Okun, A.4    Zolotarev, O.5    Silberman, I.6
  • 41
    • 34547823575 scopus 로고    scopus 로고
    • Cannabinoids ameliorate cerebral dysfunction following liver failure via AMP-activated protein kinase
    • Dagon Y., Avraham Y., Ilan Y., Mechoulam R., Berry E.M. Cannabinoids ameliorate cerebral dysfunction following liver failure via AMP-activated protein kinase. FASEB J 2007, 21:2431-2441.
    • (2007) FASEB J , vol.21 , pp. 2431-2441
    • Dagon, Y.1    Avraham, Y.2    Ilan, Y.3    Mechoulam, R.4    Berry, E.M.5
  • 42
    • 85047690626 scopus 로고    scopus 로고
    • The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
    • Cota D., Marsicano G., Tschöp M., Grübler Y., Flachskamm C., Schubert M., et al. The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 2003, 112:423-431.
    • (2003) J Clin Invest , vol.112 , pp. 423-431
    • Cota, D.1    Marsicano, G.2    Tschöp, M.3    Grübler, Y.4    Flachskamm, C.5    Schubert, M.6
  • 43
    • 20944436157 scopus 로고    scopus 로고
    • Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
    • Osei-Hyiaman D., DePetrillo M., Pacher P., Liu J., Radaeva S., Bátkai S., et al. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest 2005, 115:1298-1305.
    • (2005) J Clin Invest , vol.115 , pp. 1298-1305
    • Osei-Hyiaman, D.1    DePetrillo, M.2    Pacher, P.3    Liu, J.4    Radaeva, S.5    Bátkai, S.6
  • 44
    • 51349153318 scopus 로고    scopus 로고
    • Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice
    • Osei-Hyiaman D., Liu J., Zhou L., Godlewski G., Harvey-White J., Jeong W.I., et al. Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice. J Clin Invest 2008, 118:3160-3169.
    • (2008) J Clin Invest , vol.118 , pp. 3160-3169
    • Osei-Hyiaman, D.1    Liu, J.2    Zhou, L.3    Godlewski, G.4    Harvey-White, J.5    Jeong, W.I.6
  • 48
    • 38649114788 scopus 로고    scopus 로고
    • Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver
    • Jeong W.I., Osei-Hyiaman D., Park O., Liu J., Bátkai S., Mukhopadhyay P., et al. Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. Cell Metab 2008, 7:227-235.
    • (2008) Cell Metab , vol.7 , pp. 227-235
    • Jeong, W.I.1    Osei-Hyiaman, D.2    Park, O.3    Liu, J.4    Bátkai, S.5    Mukhopadhyay, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.