Differences in the structure and dynamics of the apo- and palmitate-ligated forms of Aedes aegypti sterol carrier protein 2 (AeSCP-2)

Journal of Biological Chemistry

Volumn 285, Issue 22, 2010, Pages 17046-17053

  Singarapu, Kiran K ^a   Radek, James T ^a   Tonelli, Marco ^a   Markley, John L ^a   Lan, Que ^a  

^a NONE

Author keywords

Aedes aegypti; Insect; Ligand binding protein; Lipid transport; Lipid binding protein; NMR structures; Palmitic acid; Protein structure; Sterol carrier protein 2 (SCP SCP 2)

Indexed keywords

AEDES AEGYPTI; CARRIER PROTEINS; LIGAND-BINDING PROTEINS; LIPID TRANSPORT; LIPID-BINDING PROTEINS; NMR STRUCTURES; PALMITIC ACID; PROTEIN STRUCTURES;

ALCOHOLS; AMINO ACIDS; FATTY ACIDS; LIGANDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGANIC ACIDS; QUANTUM THEORY;

PROTEINS;

NITROGEN 15; PALMITIC ACID; STEROL CARRIER PROTEIN 2;

AEDES AEGYPTI; ALPHA HELIX; ARTICLE; BETA SHEET; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HETERONUCLEAR SINGLE QUANTUM COHERENCE; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LIPID INTERACTION; PROTEIN POLYMORPHISM; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE;

AEDES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOENZYMES; CARRIER PROTEINS; FATTY ACIDS; GENE EXPRESSION REGULATION; GENETIC TECHNIQUES; LIGANDS; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; PALMITIC ACID; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY;

AEDES AEGYPTI; HEXAPODA; VERTEBRATA;

EID: 77952757508     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.101154     Document Type: Article

References (48)

1. Krebs K. C., Lan Q.(2003 ) Insect. Mol. Biol. 12, 51-60
2. Gallegos A. M., Atshaves B. P., Storey S. M., Starodub O., Petrescu A. D., Huang H., McIntosh A. L., Martin G. G., Chao H., Kier A. B., Schroeder F.(2001 ) Prog. Lipid Res. 40, 498-563
3. Ohba T., Rennert H., Pfeifer S. M., He Z., Yamamoto R., Holt J. A., Billheimer J. T., Strauss J. F. 3rd (1994 ) Genomics 24, 370-374
4. Seedorf U., Raabe M., Ellinghaus P., Kannenberg F., Fobker M., Engel T., Denis S., Wouters F., Wirtz K. W., Wanders R. J., Maeda N., Assmann G.(1998 ) Genes Dev. 12, 1189-1201
5. Kannenberg F., Ellinghaus P., Assmann G., Seedorf U.(1999 ) J. Biol. Chem. 274, 35455-35460
6. Fuchs M., Hafer A., Münch C., Kannenberg F., Teichmann S., Scheibner J., Stange E. F., Seedorf U.(2001 ) J. Biol. Chem. 276, 48058-48065
7. Atshaves B. P., McIntosh A. L., Landrock D., Payne H. R., Mackie J. T., Maeda N., Ball J., Schroeder F., Kier A. B.(2007 ) Am. J. Physiol. Gastrointest. Liver Physiol. 292, G939-G951
8. Ferdinandusse S., Kostopoulos P., Denis S., Rusch H., Overmars H., Dillmann U., Reith W., Haas D., Wanders R. J., Duran M., Marziniak M.(2006 ) Am. J. Hum. Genet. 78, 1046-1052
9. Ko M. H., Puglielli L.(2007 ) J. Biol. Chem. 282, 19742-19752
10. Blitzer E. J., Vyazunova I., Lan Q.(2005 ) Insect Mol. Biol. 14, 301-307
11. Dyer D. H., Wessely V., Forest K. T., Lan Q.(2008 ) J. Lipid Res. 49, 644-653
12. Kim M. S., Wessely V., Lan Q.(2005 ) J. Lipid Res. 46, 650-657
13. Larson R. T., Lorch J. M., Pridgeon J. W., Becnel J. J., Clark G. G., Lan Q.(2010 ) J. Med. Entomol. 47, 249-257
14. Dyer D. H., Lovell S., Thoden J. B., Holden H. M., Rayment I., Lan Q.(2003 ) J. Biol. Chem. 278, 39085-39091
15. García F. L., Szyperski T., Dyer J. H., Choinowski T., Seedorf U., Hauser H., Wüthrich K.(2000 ) J. Mol. Biol. 295, 595-603
16. Szyperski T., Scheek S., Johansson J., Assmann G., Seedorf U., Wüthrich K.(1993 ) FEBS. Lett. 335, 18-26
17. Stolowich N. J., Frolov A., Atshaves B., Murphy E. J., Jolly C. A., Billheimer J. T., Scott A. I., Schroeder F.(1997 ) Biochemistry 36, 1719-1729
18. Filipp F. V., Sattler M.(2007 ) Biochemistry 46, 7980-7991
19. Dyer D. H., Vyazunova I., Lorch J. M., Forest K. T., Lan Q.(2009 ) Mol. Cell. Biochem. 326, 67-77
20. Sattler M., Schleucher J., Griesinger C.(1999 ) Prog. Nucl. Mag. Res. Sp. 34, 93-158
21. Delaglio F., Grzesiek S., Vuister G. W., Zhu G., Pfeifer J., Bax A.(1995 ) J. Biomol. NMR 6, 277-293
22. Bartels C., Xia T. H., Billeter M., Güntert P., Wüthrich K.(1995 ) J. Biomol. NMR 6, 1-10
23. Bahrami A., Assadi A. H., Markley J. L., Eghbalnia H. R.(2009 ) PLoS. Comput. Biol. 5, e1000307
24. Kay L. E., Keifer P., Saarinen T.(1992 ) J. Am. Chem. Soc. 114, 10663-10665
25. Stuart A. C., Borzilleri K. A., Withka J. M., Palmer A. G. 3rd (1999 ) J. Am. Chem. Soc. 121, 5346-5347
26. Farrow N. A., Muhandiram R., Singer A. U., Pascal S. M., Kay C. M., Gish G., Shoelson S. E., Pawson T., Forman-Kay J. D., Kay L. E.(1994 ) Biochemistry 33, 5984-6003
27. Cole R., Loria J. P.(2003 ) J. Biomol. NMR 26, 203-213
28. Mandel A. M., Akke M., Palmer A. G. 3rd(1995 ) J. Mol. Biol. 246, 144-163
29. Palmer A. G., Rance M., Wright P. E.(1991 ) J. Am. Chem. Soc. 113, 4371-4380
30. Lukin J. A., Kontaxis G., Simplaceanu V., Yuan Y., Bax A., Ho C.(2003 ) Proc. Natl. Acad. Sci. U.S.A. 100, 517-520
31. Shen Y., Delaglio F., Cornilescu G., Bax A.(2009 ) J. Biomol. NMR 44, 213-223
32. Cornilescu G., Delaglio F., Bax A.(1999 ) J. Biomol. NMR 13, 289-302
33. Güntert P.(2004 ) Methods Mol. Biol. 278, 353-378
34. Zweckstetter M.(2008 ) Nat. Protoc. 3, 679-690
35. Koradi R., Billeter M., Wüthrich K.(1996 ) J. Mol. Graph. 14, 51-55
36. DeLano W. L.(2002 ) The PyMOL Molecular Graphics System, DeLano Scientific LLC, San Carlos, CA
37. Bhattacharya A., Tejero R., Montelione G. T.(2007 ) Proteins 66, 778-795
38. Sussman J. L., Lin D., Jiang J., Manning N. O., Prilusky J., Ritter O., Abola E. E.(1998 ) Acta Crystallogr. D Biol. Crystallogr. 54, 1078-1084
39. Ulrich E. L., Akutsu H., Doreleijers J. F., Harano Y., Ioannidis Y. E., Lin J., Livny M., Mading S., Maziuk D., Miller Z., Nakatani E., Schulte C. F., Tolmie D. E., Kent Wenger R., Yao H., Markley J. L.(2008 ) Nucleic Acids Res. 36, D402-D408
40. Lücke C., Rademacher M., Zimmerman A. W., van Moerkerk H. T., Veerkamp J. H., Rüterjans H.(2001 ) Biochem. J. 354, 259-266
41. Lücke C., Zhang F., Rüterjans H., Hamilton J. A., Sacchettini J. C.(1996 ) Structure 4, 785-800
42. Hodsdon M. E., Ponder J. W., Cistola D. P.(1996 ) J. Mol. Biol. 264, 585-602
43. Holm L., Sander C.(1995 ) Trends Biochem. Sci. 20, 478-480
44. Choinowski T., Hauser H., Piontek K.(2000 ) Biochemistry 39, 1897-1902
45. Davis I. W., Leaver-Fay A., Chen V. B., Block J. N., Kapral G. J., Wang X., Murray L. W., Arendall W. B. 3rd, Snoeyink J., Richardson J. S., Richardson D. C.(2007 ) Nucleic Acids Res. 35, W375-W383
46. Hagelueken G., Adams T. M., Wiehlmann L., Widow U., Kolmar H., Tümmler B., Heinz D. W., Schubert W. D.(2006 ) Proc. Natl. Acad. Sci. U.S.A. 103, 7631-7636
47. Gille C., Frömmel C.(2001 ) Bioinformatics 17, 377-378
48. Laskowski R. A., Rullmannn J. A., MacArthur M. W., Kaptein R., Thornton J. M.(1996 ) J. Biomol. NMR 8, 477-486